ENSG00000283341:+:11:43750910:43754121

1. Sequences

id gene transcript strand chrom startGR endGR length seq type
ENSG00000283341:+:11:43750910:43754121 ENSG00000283341 ENST00000532864 + 11 43750911 43754121 123 UUGUCACAGGUAGUACUGAUGGAAUUGGAAAAUCAUAUGCAGAAGAGUUAGCAAAGCAUGGAAUGAAGGUUGUCCUUAUCAGCAGAUCAAAGGAUAAACUUGACCAGGUUUCCAGUGAAAUAAUUGUCACAGGUAGUACUGAUGGAAUUGGAAAAUCAUAUGCAGAAGAGUUA circ
ENSG00000283341:+:11:43750910:43754121 ENSG00000283341 ENST00000532864 + 11 43750911 43754121 22 CAGUGAAAUAAUUGUCACAGGU bsj
ENSG00000283341:+:11:43750910:43754121 ENSG00000283341 ENST00000532864 + 11 43750711 43750920 210 UAACACUUGGUUUUGAAGUCUUUUUAAAAUUUUAGCUAUUGCGGUGUGUAUUCAACCUUAGAUUUGAACCGCUGGUAUUGUUCUGUCUUUUACAUCAAAGUGUCACACUGGUCCUUUUGUAUGUAAUUGGUGGGUCCUAACUAUGACCAAUUCCUCAAUGUAAUUCUUAGACUAAACUAUUGCUUUUUUCCCUUUCCCAGUUGUCACAGG ie_up
ENSG00000283341:+:11:43750910:43754121 ENSG00000283341 ENST00000532864 + 11 43754112 43754321 210 AGUGAAAUAAGUAAGUUCUCACAUCAAACAAAAGGAAUACAUAGCUAAUUAAUGUUUUCAAGCAGUUAUCCGAUACUGACAUAGUUAUUUCUAGUUCAGGAAACUUCUUUUUCAAGGAGAGAUAUCAUUAAAGAGCAUGAAAAAGCACAGGAUGCUUUAAAAAUGGAUCAUCAAUUUUAGGCUGGGUGCGGUGGCUCACGCCUGUAAUCC ie_down
  • Note:
    • id: unique identifier.
    • gene: represents the gene from which the circRNA arises.
    • transcript: transcript whose exon coordinates overlap with the detected back-spliced junction coordinate and used in the downstream analysis.
    • strand: is the strand from which the gene is transcribed.
    • chrom: is the chromosome from which the circRNA is derived.
    • startGR: is the 5’ coordinate of the genomic range from which the sequence are extracted.
    • endGR: is the 3’ coordinate of the genomic range from which the sequence are extracted.
    • length: length of the extracted sequences.
    • seq: sequence used in the downstream analysis.
    • type: type of sequences retrieved. If type = “circ” the sequences derive from the internal circRNA sequences. If type = “bsj” the sequences derive from the back spliced junctions (BSJ). If type = “ie_up” the Intron or Exon sequences derive from the up-stream of BSJ up to 210 bp. If type = “ie_down” the Intron or Exon sequences derive from the down-stream of BSJ up to 210 bp.

2. RNA Binding Proteins Analysis

RBP on full sequence

Plot

Spreadsheet

id foreground background foregroundNorm backgroundNorm log2FC motifF motifB
AGO1 3 548 0.03252033 0.000795613 5.353131 AGGUAG,GGUAGU,GUAGUA AGGUAG,GAGGUA,GGUAGU,GUAGUA,UGAGGU
RBFOX1 1 1077 0.01626016 0.001562242 3.379652 AGCAUG AGCAUG,GCAUGA,GCAUGC,GCAUGU,UGACUG,UGCAUG
A1CF 2 1642 0.02439024 0.002381042 3.356639 AUAAUU,UAAUUG AGUAUA,AUAAUU,AUCAGU,CAGUAU,GAUCAG,UAAUUA,UAAUUG,UCAGUA,UGAUCA,UUAAUU
G3BP2 2 1644 0.02439024 0.002383941 3.354884 AGGAUA,GGAUAA AGGAUA,AGGAUG,AGGAUU,GGAUAA,GGAUAG,GGAUGA,GGAUGG,GGAUUA,GGAUUG
EIF4B 1 1179 0.01626016 0.001710061 3.249222 UUGGAA CUCGGA,CUUGGA,GUCGGA,GUUGGA,UCGGAA,UCGGAC,UUGGAA,UUGGAC
PABPN1 1 1222 0.01626016 0.001772376 3.197585 AGAAGA AAAAGA,AGAAGA
SNRNP70 1 1237 0.01626016 0.001794114 3.179998 GAUCAA AAUCAA,AUCAAG,AUUCAA,GAUCAA,GUUCAA,UUCAAG
KHDRBS2 2 1858 0.02439024 0.002694070 3.178445 AUAAAC,GAUAAA AAUAAA,AUAAAA,AUAAAC,GAUAAA,UUUUUU
ACO1 1 1283 0.01626016 0.001860778 3.127364 CAGUGA CAGUGA,CAGUGC,CAGUGG,CAGUGU
RBM46 6 4554 0.05691057 0.006601124 3.107913 AAUCAU,AAUGAA,AUCAAA,AUCAUA,AUGAAG,GAUCAA AAUCAA,AAUCAU,AAUGAA,AAUGAU,AUCAAA,AUCAAG,AUCAAU,AUCAUA,AUCAUG,AUCAUU,AUGAAA,AUGAAG,AUGAAU,AUGAUA,AUGAUG,AUGAUU,GAUCAA,GAUCAU,GAUGAA,GAUGAU
QKI 3 2805 0.03252033 0.004066466 2.999494 AAUCAU,AUCAUA,UCAUAU AAUCAU,ACACAC,ACACUA,ACUAAC,ACUAAU,ACUCAU,ACUUAU,AUCAUA,AUCUAA,AUCUAC,AUUAAC,CACACU,CACUAA,CUAACA,CUAACC,CUAACG,CUAAUC,CUACUC,CUCAUA,UAACCU,UAAUCA,UACUCA,UCAUAU,UCUAAU,UCUACU
KHDRBS3 3 3429 0.03252033 0.004970770 2.709801 AAAUAA,AUAAAC,GAUAAA AAAUAA,AAUAAA,AGAUAA,AUAAAA,AUAAAC,AUAAAG,AUUAAA,GAUAAA,UAAAAC,UAAAUA,UUAAAC,UUUUUU
ZNF638 1 1773 0.01626016 0.002570888 2.661003 GGUUGU CGUUCG,CGUUCU,CGUUGG,CGUUGU,GGUUCG,GGUUCU,GGUUGG,GGUUGU,GUUCGU,GUUCUU,GUUGGU,GUUGUU,UGUUCG,UGUUCU,UGUUGG,UGUUGU
MSI1 2 2770 0.02439024 0.004015744 2.602565 AGGUAG,AGUUAG AGGAAG,AGGAGG,AGGUAG,AGGUGG,AGUAAG,AGUAGG,AGUUAG,AGUUGG,UAGGAA,UAGGAG,UAGGUA,UAGGUG,UAGUAA,UAGUAG,UAGUUA,UAGUUG
ZRANB2 2 3173 0.02439024 0.004599773 2.406670 AGGUAG,AGGUUU AAAGGU,AGGGAA,AGGUAA,AGGUAC,AGGUAG,AGGUAU,AGGUCU,AGGUUA,AGGUUU,CGGUAA,CGGUAG,CGGUAU,CGGUCU,GAGGUU,GGGUAA,GGGUGA,GGUAAA,GGUGGU,GUAAAG,GUGGUG,UAAAGG,UGGUAA,UGGUGG
DAZAP1 4 5964 0.04065041 0.008644502 2.233415 AGGAUA,AGGUAG,AGGUUG,AGUUAG AAAAAA,AAUUUA,AGAUAU,AGGAAA,AGGAAG,AGGAUA,AGGAUG,AGGUAA,AGGUAG,AGGUUA,AGGUUG,AGUAAA,AGUAAG,AGUAGG,AGUAUA,AGUAUG,AGUUAA,AGUUAG,AGUUUA,AGUUUG,GGGGGG,GUAACG,UAGGAA,UAGGAU,UAGGUA,UAGGUU,UAGUAA,UAGUAU,UAGUUA,UAGUUU,UUUUUU
PABPC5 1 2400 0.01626016 0.003479539 2.224374 GAAAAU AGAAAA,AGAAAG,AGAAAU,GAAAAU,GAAAGU,GAAAUU
IGF2BP3 3 4815 0.03252033 0.006979366 2.220174 AAAAUC,AAAUCA AAAAAC,AAAACA,AAAAUC,AAACAC,AAACUC,AAAUAC,AAAUCA,AAAUUC,AACACA,AACUCA,AAUACA,AAUUCA,ACAAAC,ACAAUC,ACACAC,ACACUC,ACAUAC,ACAUUC,CAAACA,CAAUCA,CACACA,CACUCA,CAUACA,CAUUCA
TARDBP 1 2654 0.01626016 0.003847636 2.079297 GAAUGA GAAUGA,GAAUGG,GAAUGU,GUGAAU,GUGUGU,GUUGUG,GUUGUU,GUUUUG,UGAAUG,UGUGUG,UUGUGC,UUGUUC,UUUUGC
SRSF4 1 3740 0.01626016 0.005421472 1.584585 AGAAGA AAGAAG,AGAAGA,AGGAAG,GAAGAA,GAGGAA,GGAAGA
PUM1 2 5823 0.02439024 0.008440164 1.530961 AAUUGU,GAAUUG AAUAUU,AAUGUU,AAUUGU,ACAUAA,AGAAUU,AGAUAA,AUUGUA,CAGAAU,CCAGAA,CUUGUA,GAAUUG,GUAAAU,GUAAUA,GUACAU,GUAGAU,GUAUAU,GUCCAG,UAAAUA,UAAUAU,UAAUGU,UACAUA,UACAUC,UAGAUA,UAUAUA,UGUAAA,UGUAAU,UGUACA,UGUAGA,UGUAUA,UGUCCA,UUAAUG,UUGUAC,UUGUAG,UUUAAU
NOVA2 1 4013 0.01626016 0.005817105 1.482969 AGAUCA AACACC,ACCACC,AGACAU,AGAUCA,AGCACC,AGGCAU,AGUCAU,AUCAAC,AUCACC,AUCAUC,CCUAGA,CUAGAU,GAGACA,GAGGCA,GAGUCA,GAUCAC,GGGGGG,UAGAUC,UUUUUU
IGF2BP2 3 8408 0.03252033 0.012186356 1.416075 AAAAUC,AAAUCA AAAAAC,AAAACA,AAAAUC,AAACAC,AAACUC,AAAUAC,AAAUCA,AAAUUC,AACACA,AACUCA,AAUACA,AAUUCA,ACAAAC,ACAAUC,ACACAC,ACACUC,ACAUAC,ACAUUC,CAAAAC,CAAACA,CAAAUC,CAACAC,CAACUC,CAAUAC,CAAUCA,CAAUUC,CACACA,CACUCA,CAUACA,CAUUCA,CCAAAC,CCAAUC,CCACAC,CCACUC,CCAUAC,CCAUUC,GAAAAC,GAAAUC,GAACAC,GAACUC,GAAUAC,GAAUUC,GCAAAC,GCAAUC,GCACAC,GCACUC,GCAUAC,GCAUUC
TRA2A 2 6871 0.02439024 0.009958930 1.292242 AGAAGA,GAAGAG AAAGAA,AAGAAA,AAGAAG,AAGAGG,AGAAAG,AGAAGA,AGAGGA,AGGAAG,GAAAGA,GAAGAA,GAAGAG,GAGGAA
RBMX 1 4925 0.01626016 0.007138779 1.187593 AUCAAA AAGAAG,AAGGAA,AAGUAA,AAGUGU,ACCAAA,AGAAGG,AGGAAG,AGUAAC,AGUGUU,AUCAAA,AUCCCA,AUCCCC,GAAGGA,GGAAGG,GUAACA,UAACAA,UAAGAC,UCAAAA
SF1 1 4931 0.01626016 0.007147474 1.185836 UACUGA ACAGAC,ACAGUC,ACCGAC,ACGAAC,ACUAAC,ACUAAG,ACUAAU,ACUAGC,ACUGAC,ACUUAU,AGUAAC,AGUAAG,AUACUA,AUUAAC,CACAGA,CACCGA,CACUGA,CAGUCA,CGCUGA,CUAACA,GACUAA,GCUAAC,GCUGAC,GCUGCC,UAACAA,UACGAA,UACUAA,UACUAG,UACUGA,UAGUAA,UAUACU,UGCUAA,UGCUGA,UGCUGC
HNRNPL 1 5085 0.01626016 0.007370651 1.141478 AAAUAA AAACAA,AAACAC,AAAUAA,AAAUAC,AACAAA,AACACA,AAUAAA,AAUACA,ACACAA,ACACAC,ACACCA,ACACGA,ACAUAA,ACAUAC,ACCACA,CACAAA,CACAAC,CACAAG,CACACA,CACACC,CACCAC,CACGAA,CACGAC,CACGAG,CAUAAA,CAUACA
YTHDC1 1 5576 0.01626016 0.008082210 1.008520 UAGUAC GAAUAC,GAAUGC,GACUAC,GACUGC,GAGUAC,GAGUGC,GCAUAC,GCAUGC,GCCUAC,GCCUGC,GCGUAC,GCGUGC,GGAUAC,GGAUGC,GGCUAC,GGCUGC,GGGUAC,GGGUGC,UAAUAC,UAAUGC,UACUAC,UACUGC,UAGUAC,UAGUGC,UCAUAC,UCAUGC,UCCUAC,UCCUGC,UCGUAC,UCGUGC,UGAUAC,UGAUGC,UGCUAC,UGCUGC,UGGUAC,UGGUGC

RBP on BSJ (Exon Only)

Plot

Spreadsheet

id foreground background foregroundNorm backgroundNorm log2FC motifF motifB
A1CF 2 3 0.13636364 0.0002619859 9.023754 AUAAUU,UAAUUG AUCAGU,CAGUAU,UAAUUG
PUM1 1 16 0.09090909 0.0011134399 6.351329 AAUUGU AAUAUU,AAUGUU,AAUUGU,ACAUAA,AGAUAA,CAGAAU,GUAAAU,GUCCAG,UAAAUA,UAUAUA,UGUAAA,UGUAGA,UGUAUA,UUAAUG
PPIE 2 61 0.13636364 0.0040607807 5.069558 AAUAAU,AUAAUU AAAAAA,AAAAAU,AAAAUA,AAAAUU,AAAUAA,AAAUAU,AAAUUA,AAAUUU,AAUAAU,AAUAUA,AAUAUU,AAUUAA,AAUUAU,AAUUUA,AAUUUU,AUAAAU,AUAAUA,AUAUAA,AUAUAU,AUAUUU,AUUAAA,AUUUAA,UAAAAA,UAAAUA,UAAAUU,UAUAAA,UAUAAU,UAUAUA,UAUAUU,UAUUAA,UAUUUU,UUAAAA,UUAAAU,UUAUUA
SFPQ 1 153 0.09090909 0.0100864553 3.172005 UAAUUG AAGAAC,AAGAGC,AAGAGG,AAGCAA,AAGGAA,AAGGAC,AAGGGA,ACUGGG,AGAGAG,AGAGGA,AGAGGU,AGGAAC,AGGACC,AGGGAU,AGGGGG,AUCGGA,CAGGCA,CUGGAG,CUGGGA,GAAGAA,GAAGAG,GAAGCA,GAAGGA,GAGGAA,GAGGAC,GAGGUA,GCAGGC,GGAAGA,GGAGAG,GGAGGA,GGAGGG,GGGGGA,GUAAGA,GUAAUG,GUAGUG,GUAGUU,GUCUGG,GUGAUU,UAAGAG,UAAGGA,UAAGGG,UAAUGG,UAAUUG,UAGAGA,UAGAUC,UAGUGG,UAGUGU,UAGUUG,UCGGAA,UCUAAG,UGAAGC,UGAUGG,UGAUGU,UGAUUG,UGCAGG,UGGAGA,UGGAGC,UGGAGG,UGGUUU,UUAAUG,UUAGUG,UUAGUU,UUGAAG,UUGGUU

RBP on BSJ (Exon and Intron)

Plot

Spreadsheet

id foreground background foregroundNorm backgroundNorm log2FC motifF motifB
SRP14 3 218 0.009523810 0.0011033857 3.109602 CCUGUA,CGCCUG,GCCUGU CCUGUA,CGCCUG,CUGUAG,GCCUGU
SNRNP70 3 253 0.009523810 0.0012797259 2.895704 AUUCAA,UUCAAG AAUCAA,AUCAAG,AUUCAA,GAUCAA,GUUCAA,UUCAAG
SNRPB2 3 288 0.009523810 0.0014560661 2.709463 GUAUUG,UAUUGC AUUGCA,GUAUUG,UAUUGC,UGCAGU,UUGCAG
TUT1 2 230 0.007142857 0.0011638452 2.617602 CGAUAC,GAUACU AAAUAC,AAUACU,AGAUAC,CAAUAC,CGAUAC,GAUACU
IGF2BP1 1 173 0.004761905 0.0008766626 2.441445 AAGCAC AAGCAC,ACCCGU,AGCACC,CACCCG,CCCGUU,GCACCC
YBX2 2 263 0.007142857 0.0013301088 2.424957 ACAUCA AACAAC,AACAUC,ACAACA,ACAACG,ACAACU,ACAUCA,ACAUCG,ACAUCU
RBFOX1 2 287 0.007142857 0.0014510278 2.299426 AGCAUG,GCAUGA AGCAUG,GCAUGA,GCAUGC,GCAUGU,UGACUG,UGCAUG
HNRNPA0 1 200 0.004761905 0.0010126965 2.233337 AGAUAU AAUUUA,AGAUAU,AGUAGG
RBM3 4 541 0.011904762 0.0027307537 2.124168 AAACUA,AGACUA,GAAACU,GAUACU AAAACG,AAAACU,AAACGA,AAACUA,AAGACG,AAGACU,AAUACG,AAUACU,AGACGA,AGACUA,AUACGA,AUACUA,GAAACG,GAAACU,GAGACG,GAGACU,GAUACG,GAUACU
HNRNPM 1 222 0.004761905 0.0011235389 2.083489 AAGGAA AAGGAA,GAAGGA,GGGGGG
HNRNPA3 2 349 0.007142857 0.0017634019 2.018140 AAGGAG,CAAGGA AAGGAG,AGGAGC,CAAGGA,CCAAGG,GCCAAG,GGAGCC
RBM46 6 1091 0.016666667 0.0055018138 1.598986 AUCAAA,AUCAAU,AUCAUU,AUGAAA,GAUCAU AAUCAA,AAUCAU,AAUGAA,AAUGAU,AUCAAA,AUCAAG,AUCAAU,AUCAUA,AUCAUG,AUCAUU,AUGAAA,AUGAAG,AUGAAU,AUGAUA,AUGAUG,AUGAUU,GAUCAA,GAUCAU,GAUGAA,GAUGAU
RBM41 2 502 0.007142857 0.0025342604 1.494937 AUACAU,UUACAU AUACAU,AUACUU,UACAUG,UACAUU,UACUUG,UACUUU,UUACAU,UUACUU
SAMD4A 3 790 0.009523810 0.0039852882 1.256855 CUGGUA,CUGGUC,GCUGGU CGGGAA,CGGGAC,CGGGCA,CGGGCC,CGGGUA,CGGGUC,CUGGAA,CUGGAC,CUGGCA,CUGGCC,CUGGUA,CUGGUC,GCGGGA,GCGGGC,GCGGGU,GCUGGA,GCUGGC,GCUGGU
A1CF 2 598 0.007142857 0.0030179363 1.242939 UAAUUA,UAAUUG AGUAUA,AUAAUU,AUCAGU,CAGUAU,GAUCAG,UAAUUA,UAAUUG,UCAGUA,UGAUCA,UUAAUU
RC3H1 2 631 0.007142857 0.0031841999 1.165570 UCCCUU,UUCUGU CCCUUC,CCUUCU,CUUCUG,UCCCUU,UCUGUG,UUCUGU
U2AF2 4 1071 0.011904762 0.0054010480 1.140228 UUUUCC,UUUUUC,UUUUUU UUUUCC,UUUUUC,UUUUUU
RBMX 5 1316 0.014285714 0.0066354293 1.106311 AAGGAA,AAGUAA,AAGUGU,AUCAAA AAGAAG,AAGGAA,AAGUAA,AAGUGU,ACCAAA,AGAAGG,AGGAAG,AGUAAC,AGUGUU,AUCAAA,AUCCCA,AUCCCC,GAAGGA,GGAAGG,GUAACA,UAACAA,UAAGAC,UCAAAA
YBX1 5 1321 0.014285714 0.0066606207 1.100845 ACAUCA,AUCAUC,UGCGGU AACAUC,AACCAC,ACACCA,ACAUCA,ACAUCG,ACAUCU,ACCACA,ACCACC,AUCAUC,CAACCA,CACACC,CACCAC,CAGCAA,CAUCAU,CAUCGC,CAUCUG,CCACAA,CCACAC,CCACCA,CCAGCA,CCCUGC,CCUGCG,CUGCGG,GAUCUG,GCCUGC,GGUCUG,GUCUGC,UCCAGC,UGCGGU
PABPC4 1 462 0.004761905 0.0023327287 1.029520 AAAAAG AAAAAA,AAAAAG

Help

  • Note:
    • foreground: number of motifs found in the foreground target sequences (e.g. predicted circRNAs).
    • background: number of motifs found in the background target sequences (e.g. randomly generated circRNAs).
    • foregroundNorm: number of motifs found in the foreground target sequences (+1) divided by the number (or length) of sequences analyzed.
    • backgroundNorm: number of motifs found in background target sequences (+1) divided by the number (or length) of sequences analyzed.
    • log2FC: log2 fold change calculated in this way (foregroundNorm)/(backgroundNorm).
    • motifF: motifs of the corresponding RBP found in the foreground sequences.
    • motifB: motifs of the corresponding RBP found in the background sequences.

Back to Home