ENSG00000286619

1 Isoform Switch

Summary Plot
Results

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Rows: 1-7 / 7
Columns:
Select all:
isoform_id
gene_id
condition_1
condition_2
gene_name
gene_biotype
iso_biotype
gene_overall_mean
gene_value_1
gene_value_2
gene_stderr_1
gene_stderr_2
gene_log2_fold_change
iso_overall_mean
iso_value_1
iso_value_2
iso_stderr_1
iso_stderr_2
iso_log2_fold_change
IF_overall
IF1
IF2
dIF
isoform_switch_q_value
gene_switch_q_value
PTC
codingPotential
Close
Columns▼Records:
Use the filters above each column to filter and limit table data. Advanced searches can be performed by using the following operators:
<, <=, >, >=, =, *, !, {, }, ||,&&, **[empty]**, **[nonempty]**, **rgx:**
Learn more
TableFilter v0.7.3
https://www.tablefilter.com/
©2015-2025 Max Guglielmi
Close
?
Page of 1
isoform_id	gene_id	condition_1	condition_2	gene_biotype	iso_biotype	gene_overall_mean	gene_value_1	gene_value_2	gene_stderr_1	gene_stderr_2	gene_log2_fold_change	iso_overall_mean	iso_value_1	iso_value_2	iso_stderr_1	iso_stderr_2	iso_log2_fold_change	IF_overall	IF1	IF2	dIF	isoform_switch_q_value	gene_switch_q_value	PTC	codingPotential

ENST00000652821	ENSG00000286619	HEK293_OSMI2_6hA	HEK293_TMG_6hB	lncRNA	lncRNA	2.416753	2.955976	2.273286	0.6674508	0.1881107	-0.3773956	0.1926734	0.2074636	0.00000000	0.03909996	0.00000000	-4.4427022	0.05980000	0.08003333	0.0000000	-0.08003333	0.01597141	0.01597141		FALSE
ENST00000653906	ENSG00000286619	HEK293_OSMI2_6hA	HEK293_TMG_6hB	lncRNA	lncRNA	2.416753	2.955976	2.273286	0.6674508	0.1881107	-0.3773956	0.5894611	0.9346562	0.28272307	0.39858306	0.06344079	-1.6902529	0.19027500	0.29066667	0.1307333	-0.15993333	0.30187746	0.01597141	TRUE	TRUE
ENST00000656162	ENSG00000286619	HEK293_OSMI2_6hA	HEK293_TMG_6hB	lncRNA	lncRNA	2.416753	2.955976	2.273286	0.6674508	0.1881107	-0.3773956	0.1772314	0.0000000	0.13697220	0.00000000	0.13697220	3.8774714	0.09313333	0.00000000	0.0535000	0.05350000	0.80825626	0.01597141	TRUE	FALSE
ENST00000656452	ENSG00000286619	HEK293_OSMI2_6hA	HEK293_TMG_6hB	lncRNA	lncRNA	2.416753	2.955976	2.273286	0.6674508	0.1881107	-0.3773956	0.1129999	0.2018634	0.11467192	0.01384096	0.01671253	-0.7649978	0.05117500	0.07610000	0.0500000	-0.02610000	0.88102090	0.01597141	FALSE	TRUE
ENST00000656763	ENSG00000286619	HEK293_OSMI2_6hA	HEK293_TMG_6hB	lncRNA	lncRNA	2.416753	2.955976	2.273286	0.6674508	0.1881107	-0.3773956	0.7827455	0.5173287	1.33684866	0.27155422	0.22434902	1.3528134	0.35135000	0.23026667	0.5851000	0.35483333	0.59252100	0.01597141	TRUE	FALSE
ENST00000659861	ENSG00000286619	HEK293_OSMI2_6hA	HEK293_TMG_6hB	lncRNA	lncRNA	2.416753	2.955976	2.273286	0.6674508	0.1881107	-0.3773956	0.1147831	0.1699479	0.05088458	0.16994786	0.05088458	-1.5634302	0.05272917	0.06820000	0.0265000	-0.04170000	1.00000000	0.01597141		FALSE
ENST00000669196	ENSG00000286619	HEK293_OSMI2_6hA	HEK293_TMG_6hB	lncRNA	lncRNA	2.416753	2.955976	2.273286	0.6674508	0.1881107	-0.3773956	0.0813621	0.4766192	0.00000000	0.47661925	0.00000000	-5.6047215	0.02554167	0.11156667	0.0000000	-0.11156667	0.87848347	0.01597141		FALSE

Note:
- The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

All exons whithin this gene region are shown and numbering below.

All isoforms whithin this gene region are shown below.

Rows: 1-10 / 28
Loading extensions...
Columns:
Select all:
groupID
featureID
exonBaseMean
dispersion
pvalue
padj
seqnames
start
end
width
strand
HEK293_TMG_6hB
HEK293_OSMI2_6hA
log2fold_HEK293_OSMI2_6hA_HEK293_TMG_6hB
Close
Columns▼Records:
Use the filters above each column to filter and limit table data. Advanced searches can be performed by using the following operators:
<, <=, >, >=, =, *, !, {, }, ||,&&, **[empty]**, **[nonempty]**, **rgx:**
Learn more
TableFilter v0.7.3
https://www.tablefilter.com/
©2015-2025 Max Guglielmi
Close
?
Page of 3
groupID	featureID	exonBaseMean	dispersion	pvalue	padj	seqnames	start	end	width	strand	HEK293_TMG_6hB	HEK293_OSMI2_6hA	log2fold_HEK293_OSMI2_6hA_HEK293_TMG_6hB

ENSG00000286619	E001	0.0000000				1	205813322	205813328	7	+
ENSG00000286619	E002	0.0000000				1	205813329	205813336	8	+
ENSG00000286619	E003	0.0000000				1	205813337	205813344	8	+
ENSG00000286619	E004	0.0000000				1	205813345	205813346	2	+
ENSG00000286619	E005	0.0000000				1	205813347	205813347	1	+
ENSG00000286619	E006	0.0000000				1	205813348	205813352	5	+
ENSG00000286619	E007	1.1188791	0.0154372930	0.744635795		1	205813353	205813361	9	+	0.353	0.300	-0.338
ENSG00000286619	E008	2.5749448	0.0465547163	0.357250276	0.59346481	1	205813362	205813408	47	+	0.639	0.475	-0.759
ENSG00000286619	E009	5.8669704	0.0283946755	0.456678644	0.67078836	1	205813409	205813535	127	+	0.887	0.777	-0.429
ENSG00000286619	E010	4.7987075	0.0487433050	0.851255543	0.92571717	1	205813536	205813585	50	+	0.779	0.738	-0.165
ENSG00000286619	E011	0.3150090	0.0274424043	0.690905219		1	205836239	205836303	65	+	0.152	0.096	-0.749
ENSG00000286619	E012	0.9465047	0.0192823856	0.521498216		1	205853788	205853874	87	+	0.353	0.242	-0.754
ENSG00000286619	E013	0.1723744	0.0326491905	0.768884560		1	205857100	205857498	399	+	0.000	0.097	10.314
ENSG00000286619	E014	0.1723744	0.0326491905	0.768884560		1	205857499	205857579	81	+	0.000	0.097	10.314
ENSG00000286619	E015	1.4925826	0.0287658556	0.282484748	0.52288894	1	205858143	205858211	69	+	0.490	0.300	-1.068
ENSG00000286619	E016	3.2661599	0.0569977431	0.724564787	0.85085555	1	205858212	205858289	78	+	0.639	0.578	-0.272
ENSG00000286619	E017	1.4450344	0.0135063096	0.624295338	0.78685825	1	205858290	205858293	4	+	0.427	0.351	-0.429
ENSG00000286619	E018	1.3847472	0.0150382652	0.635578541		1	205858294	205858320	27	+	0.427	0.351	-0.430
ENSG00000286619	E019	2.5288540	0.0090105195	0.420552710	0.64406900	1	205858321	205859826	1506	+	0.427	0.573	0.711
ENSG00000286619	E020	0.9402750	0.0172671820	0.292851630		1	205862445	205862598	154	+	0.152	0.351	1.568
ENSG00000286619	E021	1.1298377	0.0149318326	0.653853816		1	205864133	205864257	125	+	0.264	0.351	0.570
ENSG00000286619	E022	0.6370325	0.0202704876	0.634582776		1	205868770	205868833	64	+	0.152	0.242	0.832
ENSG00000286619	E023	0.3751086	0.0244411696	0.391628487		1	205882421	205882514	94	+	0.000	0.176	11.263
ENSG00000286619	E024	0.6672048	0.3142738723	0.149940488		1	205882515	205882549	35	+	0.000	0.301	11.805
ENSG00000286619	E025	16.9820628	0.0480497789	0.001894721	0.01636909	1	205890047	205891155	1109	+	0.865	1.357	1.780
ENSG00000286619	E026	18.5329245	0.0058972384	0.517618826	0.71336413	1	205891156	205891309	154	+	1.228	1.290	0.221
ENSG00000286619	E027	30.5662774	0.0017299183	0.964870440	0.98437559	1	205894168	205894466	299	+	1.469	1.486	0.060
ENSG00000286619	E028	109.7275043	0.0007191601	0.022104753	0.10293952	1	205894467	205896082	1616	+	2.049	2.009	-0.135

Isoforom Switch Analysis

WANG Ziyi

Date: 19 5月 2022

ENSG00000286619

1 Isoform Switch

TableFilter v0.7.3

2 Differential Exon Usage

TableFilter v0.7.3