ENSG00000278390

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000616251 ENSG00000278390 HEK293_OSMI2_6hA HEK293_TMG_6hB lncRNA lncRNA 2.940834 1.45767 2.179894 0.03424891 0.593413 0.577333 0.2564097 0.05369557 0.4020369 0.05369557 0.2039771 2.69350867 0.08990000 0.0377 0.21530000 0.177600000 0.49884536 0.01501718   FALSE
ENST00000619407 ENSG00000278390 HEK293_OSMI2_6hA HEK293_TMG_6hB lncRNA lncRNA 2.940834 1.45767 2.179894 0.03424891 0.593413 0.577333 0.1681081 0.12851748 0.2066472 0.06590562 0.1033236 0.64527939 0.06900000 0.0903 0.09236667 0.002066667 1.00000000 0.01501718   FALSE
ENST00000620300 ENSG00000278390 HEK293_OSMI2_6hA HEK293_TMG_6hB lncRNA lncRNA 2.940834 1.45767 2.179894 0.03424891 0.593413 0.577333 0.3048869 0.35074996 0.3665463 0.08247900 0.2960313 0.06182824 0.14163750 0.2383 0.22613333 -0.012166667 0.77656931 0.01501718   FALSE
ENST00000660769 ENSG00000278390 HEK293_OSMI2_6hA HEK293_TMG_6hB lncRNA lncRNA 2.940834 1.45767 2.179894 0.03424891 0.593413 0.577333 0.9750143 0.89919623 0.3495867 0.03385806 0.1096243 -1.33825214 0.35435417 0.6170 0.18593333 -0.431066667 0.01501718 0.01501718   FALSE
MSTRG.8638.3 ENSG00000278390 HEK293_OSMI2_6hA HEK293_TMG_6hB lncRNA   2.940834 1.45767 2.179894 0.03424891 0.593413 0.577333 0.8908171 0.00000000 0.7846722 0.00000000 0.7846722 6.31228799 0.24680833 0.0000 0.23336667 0.233366667 0.90367671 0.01501718   FALSE
MSTRG.8638.7 ENSG00000278390 HEK293_OSMI2_6hA HEK293_TMG_6hB lncRNA   2.940834 1.45767 2.179894 0.03424891 0.593413 0.577333 0.2051730 0.00000000 0.0000000 0.00000000 0.0000000 0.00000000 0.05349583 0.0000 0.00000000 0.000000000   0.01501718   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_6hB HEK293_OSMI2_6hA log2fold_HEK293_OSMI2_6hA_HEK293_TMG_6hB
ENSG00000278390 E001 0.3503582 0.028369347 0.86607725   13 41132939 41132947 9 + 0.110 0.134 0.332
ENSG00000278390 E002 0.3503582 0.028369347 0.86607725   13 41132948 41132949 2 + 0.110 0.134 0.332
ENSG00000278390 E003 0.3503582 0.028369347 0.86607725   13 41132950 41132951 2 + 0.110 0.134 0.332
ENSG00000278390 E004 0.3503582 0.028369347 0.86607725   13 41132952 41132953 2 + 0.110 0.134 0.332
ENSG00000278390 E005 0.6957271 0.020982295 0.81651723   13 41132954 41132958 5 + 0.197 0.237 0.336
ENSG00000278390 E006 9.4211797 0.006204418 0.68332999 0.82479827 13 41132959 41133055 97 + 0.996 1.033 0.133
ENSG00000278390 E007 1.6973421 0.024795076 0.31950871 0.55926539 13 41134709 41134762 54 + 0.332 0.502 0.924
ENSG00000278390 E008 9.7196205 0.008463698 0.66342094 0.81206330 13 41146427 41146507 81 + 1.009 1.047 0.141
ENSG00000278390 E009 3.4581703 0.009934567 0.01077593 0.06143623 13 41146508 41146646 139 + 0.435 0.809 1.657
ENSG00000278390 E010 5.3248750 0.006984656 0.09105211 0.26558709 13 41162263 41162403 141 + 0.882 0.665 -0.869
ENSG00000278390 E011 0.3503582 0.028369347 0.86607725   13 41162981 41163019 39 + 0.110 0.134 0.332
ENSG00000278390 E012 0.1779838 0.034295105 0.59857087   13 41165551 41165608 58 + 0.110 0.000 -9.563
ENSG00000278390 E013 1.7350352 0.466833927 0.43624368 0.65598868 13 41175373 41175659 287 + 0.343 0.509 0.891
ENSG00000278390 E014 1.5475908 0.053744575 0.13310760 0.33669560 13 41187231 41187568 338 + 0.517 0.237 -1.658
ENSG00000278390 E015 0.1426347 0.033452768 0.59919418   13 41192640 41192835 196 + 0.110 0.000 -9.559
ENSG00000278390 E016 7.5191583 0.014771231 0.15721339 0.37252326 13 41235116 41236686 1571 + 0.996 0.832 -0.622