ENSG00000259768

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000668995 ENSG00000259768 HEK293_OSMI2_6hA HEK293_TMG_6hB lncRNA lncRNA 2.811527 3.098704 2.763043 0.1904259 0.2115023 -0.1648437 0.15613879 0.1297977 0.23029583 0.06507236 0.03719749 0.7814709 0.05306667 0.04216667 0.0847000 0.04253333 0.69106532 0.03321668 FALSE FALSE
ENST00000687589 ENSG00000259768 HEK293_OSMI2_6hA HEK293_TMG_6hB lncRNA lncRNA 2.811527 3.098704 2.763043 0.1904259 0.2115023 -0.1648437 0.24919568 0.2579029 0.04500077 0.05232784 0.04500077 -2.2841866 0.08454583 0.08273333 0.0151000 -0.06763333 0.17892340 0.03321668 TRUE FALSE
ENST00000692937 ENSG00000259768 HEK293_OSMI2_6hA HEK293_TMG_6hB lncRNA lncRNA 2.811527 3.098704 2.763043 0.1904259 0.2115023 -0.1648437 0.04392723 0.0000000 0.21688292 0.00000000 0.21688292 4.5038761 0.01407083 0.00000000 0.0731000 0.07310000 0.84665794 0.03321668   FALSE
MSTRG.12989.12 ENSG00000259768 HEK293_OSMI2_6hA HEK293_TMG_6hB lncRNA   2.811527 3.098704 2.763043 0.1904259 0.2115023 -0.1648437 0.40929769 0.2817725 0.62018493 0.09444142 0.21070224 1.1109316 0.13959167 0.08893333 0.2219667 0.13303333 0.40042879 0.03321668 FALSE FALSE
MSTRG.12989.3 ENSG00000259768 HEK293_OSMI2_6hA HEK293_TMG_6hB lncRNA   2.811527 3.098704 2.763043 0.1904259 0.2115023 -0.1648437 0.91439912 0.3130708 0.76949427 0.15695006 0.43062722 1.2706883 0.32892500 0.09700000 0.2840333 0.18703333 0.87347836 0.03321668 TRUE TRUE
MSTRG.12989.8 ENSG00000259768 HEK293_OSMI2_6hA HEK293_TMG_6hB lncRNA   2.811527 3.098704 2.763043 0.1904259 0.2115023 -0.1648437 0.58445605 1.2971435 0.64910529 0.24813581 0.38232455 -0.9878367 0.21557500 0.41200000 0.2367667 -0.17523333 0.76919141 0.03321668 FALSE TRUE
MSTRG.12989.9 ENSG00000259768 HEK293_OSMI2_6hA HEK293_TMG_6hB lncRNA   2.811527 3.098704 2.763043 0.1904259 0.2115023 -0.1648437 0.14045902 0.4795460 0.00000000 0.21489331 0.00000000 -5.6133725 0.04795417 0.16430000 0.0000000 -0.16430000 0.03321668 0.03321668 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

No results under this category.

Splicing

All exons whithin this gene region are shown and numbering below.

No results under this category.

Transcripts

All isoforms whithin this gene region are shown below.

No results under this category.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_6hB HEK293_OSMI2_6hA log2fold_HEK293_OSMI2_6hA_HEK293_TMG_6hB
ENSG00000259768 E001 0.1614157 0.031192256 0.251843861   16 72665123 72665127 5 +      
ENSG00000259768 E002 0.4702677 0.023535539 0.255556544   16 72665128 72665132 5 +      
ENSG00000259768 E003 0.4702677 0.023535539 0.255556544   16 72665133 72665137 5 +      
ENSG00000259768 E004 0.4702677 0.023535539 0.255556544   16 72665138 72665139 2 +      
ENSG00000259768 E005 1.6739967 0.013970140 0.777543831 0.88322526 16 72665140 72665144 5 +      
ENSG00000259768 E006 3.3989512 0.007148326 0.094868903 0.27274288 16 72665145 72665161 17 +      
ENSG00000259768 E007 5.2688029 0.008632356 0.047479273 0.17370947 16 72665162 72665167 6 +      
ENSG00000259768 E008 6.1362842 0.041701009 0.138203304 0.34480372 16 72665168 72665169 2 +      
ENSG00000259768 E009 19.3603925 0.063265527 0.002720514 0.02168670 16 72665170 72665333 164 +      
ENSG00000259768 E010 16.0321766 0.059197489 0.015542139 0.08012819 16 72713333 72713416 84 +      
ENSG00000259768 E011 6.1028403 0.008109516 0.039633728 0.15379578 16 72713947 72713989 43 +      
ENSG00000259768 E012 13.7220755 0.026516110 0.102585700 0.28639035 16 72745405 72745466 62 +      
ENSG00000259768 E013 3.1527876 0.047724522 0.486202946 0.69138902 16 72747017 72747120 104 +      
ENSG00000259768 E014 2.3794651 0.059902020 0.265637498 0.50503471 16 72747121 72747182 62 +      
ENSG00000259768 E015 2.1530574 0.044689919 0.002429948 0.01988153 16 72777567 72777720 154 +      
ENSG00000259768 E016 12.4470916 0.003905357 0.369207074 0.60342280 16 72781728 72781819 92 +      
ENSG00000259768 E017 2.0113710 0.016308850 0.269100799 0.50886351 16 72781820 72782731 912 +      
ENSG00000259768 E018 11.4828079 0.010076832 0.497036823 0.69894637 16 72787163 72787350 188 +      
ENSG00000259768 E019 1.7512976 0.177567039 0.304615563 0.54521995 16 72787351 72787662 312 +      
ENSG00000259768 E020 169.3986330 1.261186374 0.337495023 0.57587226 16 72787663 72791624 3962 +      
ENSG00000259768 E021 2.5797304 0.009009499 0.801451808 0.89715669 16 72811928 72812010 83 +      
ENSG00000259768 E022 3.7909879 0.007643906 0.639896909 0.79686147 16 72820773 72820842 70 +      
ENSG00000259768 E023 10.6038422 0.003886610 0.053977206 0.18903936 16 72820843 72822049 1207 +      
ENSG00000259768 E024 1.9872702 0.316556888 0.444882198 0.66207738 16 72822050 72822120 71 +      
ENSG00000259768 E025 2.3726879 0.199656019 0.557972456 0.74182796 16 72822121 72822781 661 +      
ENSG00000259768 E026 2.4213809 0.033126003 0.114221724 0.30618086 16 72828007 72828293 287 +