ENSG00000259363

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000559714 ENSG00000259363 HEK293_OSMI2_6hA HEK293_TMG_6hB   lncRNA lncRNA 1.862492 2.318271 1.920613 0.1532029 0.1844086 -0.2702 0.06471922 0.1762170 0.04331114 0.068283587 0.04331114 -1.8044754 0.02971250 0.07413333 0.01946667 -0.054666667 0.47275929 0.01097542   FALSE
ENST00000560059 ENSG00000259363 HEK293_OSMI2_6hA HEK293_TMG_6hB   lncRNA lncRNA 1.862492 2.318271 1.920613 0.1532029 0.1844086 -0.2702 0.13339748 0.0000000 0.00000000 0.000000000 0.00000000 0.0000000 0.06938333 0.00000000 0.00000000 0.000000000   0.01097542 FALSE FALSE
ENST00000656644 ENSG00000259363 HEK293_OSMI2_6hA HEK293_TMG_6hB   lncRNA lncRNA 1.862492 2.318271 1.920613 0.1532029 0.1844086 -0.2702 0.37946713 0.5739912 0.31368368 0.107713923 0.05676989 -0.8513621 0.20575000 0.24370000 0.16103333 -0.082666667 0.58247453 0.01097542   FALSE
ENST00000661885 ENSG00000259363 HEK293_OSMI2_6hA HEK293_TMG_6hB   lncRNA lncRNA 1.862492 2.318271 1.920613 0.1532029 0.1844086 -0.2702 0.09531103 0.2487075 0.02671354 0.132560722 0.02671354 -2.8169376 0.05562500 0.11383333 0.01683333 -0.097000000 0.45300236 0.01097542   FALSE
ENST00000664300 ENSG00000259363 HEK293_OSMI2_6hA HEK293_TMG_6hB   lncRNA lncRNA 1.862492 2.318271 1.920613 0.1532029 0.1844086 -0.2702 0.26217899 0.1954193 0.67326776 0.007819876 0.13476635 1.7338796 0.12801667 0.08523333 0.35713333 0.271900000 0.01097542 0.01097542 FALSE TRUE
ENST00000670236 ENSG00000259363 HEK293_OSMI2_6hA HEK293_TMG_6hB   lncRNA lncRNA 1.862492 2.318271 1.920613 0.1532029 0.1844086 -0.2702 0.68537065 0.7153609 0.59448432 0.153769346 0.05788156 -0.2629941 0.38243750 0.30446667 0.31400000 0.009533333 0.99954830 0.01097542 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_6hB HEK293_OSMI2_6hA log2fold_HEK293_OSMI2_6hA_HEK293_TMG_6hB
ENSG00000259363 E001 0.0000000       15 99805793 99805841 49 +      
ENSG00000259363 E002 0.0000000       15 99805928 99805951 24 +      
ENSG00000259363 E003 0.5778428 0.152271171 0.1923895108   15 99806630 99806849 220 + 0.000 0.253 10.307
ENSG00000259363 E004 0.0000000       15 99806897 99806929 33 +      
ENSG00000259363 E005 0.0000000       15 99806985 99806990 6 +      
ENSG00000259363 E006 0.6673924 0.019425530 0.5526750147   15 99806991 99807055 65 + 0.147 0.249 0.939
ENSG00000259363 E007 0.9706349 0.015610612 0.2336763041   15 99807056 99807098 43 + 0.147 0.360 1.675
ENSG00000259363 E008 2.2387830 0.062053576 0.2577333107 0.496495349 15 99807436 99807827 392 + 0.344 0.559 1.116
ENSG00000259363 E009 1.0534597 0.017267182 0.0285893094   15 99807828 99807886 59 + 0.000 0.407 13.003
ENSG00000259363 E010 0.9933601 0.017184408 0.2353964274   15 99807887 99807903 17 + 0.147 0.360 1.678
ENSG00000259363 E011 1.4982393 0.093761138 0.2639209600 0.503162442 15 99807904 99808077 174 + 0.256 0.482 1.344
ENSG00000259363 E012 1.5884091 0.184747877 0.9294115844 0.966743952 15 99808078 99808146 69 + 0.413 0.437 0.127
ENSG00000259363 E013 6.2333626 0.007243862 0.2214542578 0.455225826 15 99808147 99808302 156 + 0.736 0.888 0.598
ENSG00000259363 E014 0.3503582 0.027401480 0.7449678436   15 99809464 99810486 1023 + 0.147 0.100 -0.647
ENSG00000259363 E015 11.2818498 0.033736605 0.4341233883 0.654340718 15 99812973 99813086 114 + 1.014 1.098 0.305
ENSG00000259363 E016 1.6491737 0.015569516 0.1986493023 0.427969870 15 99816957 99817358 402 + 0.257 0.486 1.355
ENSG00000259363 E017 0.4054685 0.758404875 0.5341073738   15 99838630 99838710 81 + 0.000 0.193 11.478
ENSG00000259363 E018 4.5252390 0.074700923 0.0153790668 0.079509341 15 99838711 99839082 372 + 0.418 0.855 1.929
ENSG00000259363 E019 0.4536995 0.062493254 0.3593160132   15 99839083 99839134 52 + 0.257 0.099 -1.654
ENSG00000259363 E020 0.2922838 0.026135564 0.7483556564   15 99839135 99839220 86 + 0.147 0.099 -0.650
ENSG00000259363 E021 11.6501719 0.003852549 0.0009359374 0.009387732 15 99876953 99877148 196 + 1.254 0.954 -1.086
ENSG00000259363 E022 0.4054685 0.758404875 0.5341073738   15 99878050 99878389 340 + 0.000 0.193 11.478
ENSG00000259363 E023 6.6421883 0.012850556 0.9996055512 1.000000000 15 99880677 99880827 151 + 0.873 0.872 -0.003
ENSG00000259363 E024 1.0121411 0.017054817 0.2347266240   15 99880828 99880963 136 + 0.147 0.360 1.677
ENSG00000259363 E025 24.7583416 0.039346559 0.0152891928 0.079157848 15 99882968 99883926 959 + 1.516 1.317 -0.689
ENSG00000259363 E026 0.2027342 0.042982765 0.7110806356   15 99901396 99902234 839 + 0.000 0.100 10.868
ENSG00000259363 E027 0.0000000       15 99909083 99909968 886 +      
ENSG00000259363 E028 1.0599969 0.034918836 0.1587892975   15 99916047 99916818 772 + 0.147 0.404 1.929