ENSG00000237036

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000424191 ENSG00000237036 HEK293_OSMI2_6hA HEK293_TMG_6hB ZEB1-AS1 lncRNA lncRNA 2.074685 2.111229 2.107187 0.3052695 0.2662427 -0.002751604 0.52908306 0.5467313 0.08211706 0.1888890 0.08211706 -2.595441 0.24382500 0.2544667 0.03343333 -0.2210333 2.305443e-01 1.083812e-07   FALSE
ENST00000441257 ENSG00000237036 HEK293_OSMI2_6hA HEK293_TMG_6hB ZEB1-AS1 lncRNA lncRNA 2.074685 2.111229 2.107187 0.3052695 0.2662427 -0.002751604 0.03866089 0.3092871 0.00000000 0.3092871 0.00000000 -4.996783 0.01420417 0.1136333 0.00000000 -0.1136333 8.869547e-01 1.083812e-07   FALSE
ENST00000607166 ENSG00000237036 HEK293_OSMI2_6hA HEK293_TMG_6hB ZEB1-AS1 lncRNA lncRNA 2.074685 2.111229 2.107187 0.3052695 0.2662427 -0.002751604 0.78526687 0.9883191 0.73026516 0.1159930 0.17826110 -0.431459 0.41563750 0.5002333 0.38286667 -0.1173667 8.463740e-01 1.083812e-07 FALSE FALSE
ENST00000659795 ENSG00000237036 HEK293_OSMI2_6hA HEK293_TMG_6hB ZEB1-AS1 lncRNA lncRNA 2.074685 2.111229 2.107187 0.3052695 0.2662427 -0.002751604 0.26240553 0.0000000 0.62573144 0.0000000 0.10944704 5.990346 0.11721250 0.0000000 0.30376667 0.3037667 1.083812e-07 1.083812e-07   FALSE
ENST00000691219 ENSG00000237036 HEK293_OSMI2_6hA HEK293_TMG_6hB ZEB1-AS1 lncRNA lncRNA 2.074685 2.111229 2.107187 0.3052695 0.2662427 -0.002751604 0.17161020 0.0000000 0.40869402 0.0000000 0.20512332 5.387824 0.07071250 0.0000000 0.17246667 0.1724667 2.337149e-01 1.083812e-07   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_6hB HEK293_OSMI2_6hA log2fold_HEK293_OSMI2_6hA_HEK293_TMG_6hB
ENSG00000237036 E001 0.0000000       10 31206278 31206482 205 -      
ENSG00000237036 E002 0.3447487 0.337079081 0.352410778   10 31307717 31307992 276 - 0.000 0.204 9.840
ENSG00000237036 E003 3.0112977 0.008719164 0.001916836 0.01651897 10 31307993 31308152 160 - 0.232 0.758 2.747
ENSG00000237036 E004 2.1550354 0.117614621 0.186527332 0.41247762 10 31309893 31310015 123 - 0.315 0.597 1.469
ENSG00000237036 E005 33.6461926 0.001543981 0.027186744 0.11884919 10 31316528 31317658 1131 - 1.599 1.489 -0.376
ENSG00000237036 E006 4.4633402 0.006367726 0.210740769 0.44268204 10 31317659 31317799 141 - 0.822 0.657 -0.670
ENSG00000237036 E007 15.3527527 0.002744931 0.003371058 0.02559500 10 31317800 31318087 288 - 1.331 1.097 -0.827
ENSG00000237036 E008 14.1868217 0.003040849 0.881131327 0.94190409 10 31318088 31318229 142 - 1.188 1.181 -0.026
ENSG00000237036 E009 13.5915284 0.002960988 0.655911639 0.80728503 10 31318230 31318357 128 - 1.136 1.181 0.162
ENSG00000237036 E010 10.5698490 0.003672590 0.710041415 0.84183111 10 31318358 31318441 84 - 1.036 1.077 0.151
ENSG00000237036 E011 5.3851941 0.005107714 0.890766728 0.94705277 10 31318442 31318451 10 - 0.798 0.820 0.088
ENSG00000237036 E012 7.7438418 0.005150469 0.723433393 0.85018241 10 31318452 31318540 89 - 0.924 0.967 0.163
ENSG00000237036 E013 7.2128991 0.007822832 0.317522873 0.55749593 10 31318541 31318737 197 - 0.844 0.968 0.470
ENSG00000237036 E014 6.2956568 0.037372588 0.392452753 0.62233877 10 31318738 31318883 146 - 0.795 0.923 0.493
ENSG00000237036 E015 3.3277525 0.022025317 0.432511446 0.65312746 10 31318884 31318895 12 - 0.581 0.708 0.547
ENSG00000237036 E016 6.5095810 0.030046044 0.123333805 0.32104902 10 31318896 31318976 81 - 0.745 0.955 0.818
ENSG00000237036 E017 3.9065052 0.007460819 0.041579871 0.15884326 10 31318977 31319092 116 - 0.493 0.801 1.333
ENSG00000237036 E018 0.5233527 0.022364917 0.464380400   10 31319515 31319881 367 - 0.232 0.113 -1.251
ENSG00000237036 E019 1.0401159 0.511015293 0.423291428   10 31320283 31320313 31 - 0.391 0.205 -1.278
ENSG00000237036 E020 1.4436790 0.568992065 0.652252524 0.80488508 10 31320314 31320447 134 - 0.323 0.433 0.635