ENSG00000233369

1 Isoform Switch

Summary Plot
Results

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

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isoform_id
gene_id
condition_1
condition_2
gene_name
gene_biotype
iso_biotype
gene_overall_mean
gene_value_1
gene_value_2
gene_stderr_1
gene_stderr_2
gene_log2_fold_change
iso_overall_mean
iso_value_1
iso_value_2
iso_stderr_1
iso_stderr_2
iso_log2_fold_change
IF_overall
IF1
IF2
dIF
isoform_switch_q_value
gene_switch_q_value
PTC
codingPotential
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isoform_id	gene_id	condition_1	condition_2	gene_name	gene_biotype	iso_biotype	gene_overall_mean	gene_value_1	gene_value_2	gene_stderr_1	gene_stderr_2	gene_log2_fold_change	iso_overall_mean	iso_value_1	iso_value_2	iso_stderr_1	iso_stderr_2	iso_log2_fold_change	IF_overall	IF1	IF2	dIF	isoform_switch_q_value	gene_switch_q_value	PTC	codingPotential

ENST00000453092	ENSG00000233369	HEK293_OSMI2_6hA	HEK293_TMG_6hB	GTF2IP4	transcribed_processed_pseudogene	transcribed_processed_pseudogene	47.09062	52.60568	47.24627	13.1975	1.400033	-0.1549869	14.28244	0.000	30.93695	0.00000	1.3801296	11.59558	0.3354750	0.0000000	0.6542000	0.6542	1.38308e-84	1.38308e-84	FALSE	TRUE
MSTRG.30034.2	ENSG00000233369	HEK293_OSMI2_6hA	HEK293_TMG_6hB	GTF2IP4	transcribed_processed_pseudogene		47.09062	52.60568	47.24627	13.1975	1.400033	-0.1549869	30.82584	51.553	15.81062	13.05394	0.5189055	-1.70453	0.6225125	0.9785667	0.3345667	-0.6440	6.55196e-20	1.38308e-84	FALSE	TRUE

Note:
- The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

All exons whithin this gene region are shown and numbering below.

All isoforms whithin this gene region are shown below.

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featureID
exonBaseMean
dispersion
pvalue
padj
seqnames
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width
strand
HEK293_TMG_6hB
HEK293_OSMI2_6hA
log2fold_HEK293_OSMI2_6hA_HEK293_TMG_6hB
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groupID	featureID	exonBaseMean	dispersion	pvalue	padj	seqnames	start	end	width	strand	HEK293_TMG_6hB	HEK293_OSMI2_6hA	log2fold_HEK293_OSMI2_6hA_HEK293_TMG_6hB

ENSG00000233369	E001	3.2544455	0.0256232499	0.0008892619	0.009006689	7	73154938	73155343	406	+	0.232	0.817	2.980
ENSG00000233369	E002	0.0000000				7	73155503	73155547	45	+
ENSG00000233369	E003	0.0000000				7	73175415	73175525	111	+
ENSG00000233369	E004	0.0000000				7	73176857	73176922	66	+
ENSG00000233369	E005	0.0000000				7	73179087	73179270	184	+
ENSG00000233369	E006	0.0000000				7	73180539	73180597	59	+
ENSG00000233369	E007	0.3393995	0.0249209784	0.1606943870		7	73182077	73182148	72	+	0.232	0.000	-11.098
ENSG00000233369	E008	5.7389195	0.0095544059	0.0552026260	0.191789598	7	73183115	73183298	184	+	0.958	0.710	-0.971
ENSG00000233369	E009	9.9242473	0.0100539893	0.2665438931	0.506040062	7	73184661	73184719	59	+	1.112	0.992	-0.437
ENSG00000233369	E010	17.8212524	0.0024599342	0.4213526550	0.644635495	7	73190066	73190137	72	+	1.316	1.251	-0.227
ENSG00000233369	E011	37.8095563	0.0016319956	0.0636957742	0.211031157	7	73191371	73191451	81	+	1.646	1.540	-0.363
ENSG00000233369	E012	89.2348162	0.0005537721	0.1280405422	0.328666228	7	73191452	73191554	103	+	1.986	1.931	-0.185
ENSG00000233369	E013	53.2679870	0.0009290106	0.9322304412	0.968246855	7	73192497	73192555	59	+	1.733	1.736	0.010
ENSG00000233369	E014	32.0593990	0.0013553622	0.0917535033	0.266936001	7	73192951	73193025	75	+	1.454	1.559	0.358
ENSG00000233369	E015	16.5839504	0.0021764192	0.3317120104	0.570577321	7	73194626	73194727	102	+	1.198	1.279	0.286
ENSG00000233369	E016	4.3149084	0.0055881043	0.7992245682	0.895850421	7	73195636	73195701	66	+	0.746	0.711	-0.145
ENSG00000233369	E017	1.2780819	0.0138710503	0.8112683168		7	73195879	73195959	81	+	0.382	0.339	-0.252
ENSG00000233369	E018	0.3206185	0.0244411696	0.1614391762		7	73195960	73196062	103	+	0.231	0.000	-11.100
ENSG00000233369	E019	0.3088520	0.0261004184	0.9000016878		7	73197964	73198019	56	+	0.131	0.112	-0.255
ENSG00000233369	E020	38.7644192	0.0015045597	0.8837621981	0.943237437	7	73198693	73198773	81	+	1.602	1.593	-0.032
ENSG00000233369	E021	112.3331176	0.0005324622	0.7760547565	0.882387524	7	73199696	73199779	84	+	2.058	2.049	-0.031
ENSG00000233369	E022	144.9792362	0.0004450025	0.5974126008	0.768604193	7	73200449	73200632	184	+	2.155	2.169	0.048
ENSG00000233369	E023	41.6468944	0.0015654964	0.1194560722	0.314971797	7	73202112	73202140	29	+	1.575	1.662	0.296
ENSG00000233369	E024	63.3963263	0.0008546410	0.3131120561	0.553367525	7	73203423	73203464	42	+	1.782	1.826	0.149
ENSG00000233369	E025	47.1014486	0.0010248161	0.6368421912	0.794942532	7	73204563	73204604	42	+	1.692	1.668	-0.083
ENSG00000233369	E026	28.9256136	0.0025225445	0.9980570056	1.000000000	7	73205383	73205458	76	+	1.470	1.469	-0.006
ENSG00000233369	E027	11.8426886	0.0029742104	0.3175406220	0.557501706	7	73206152	73207289	1138	+	1.049	1.147	0.351

Isoforom Switch Analysis

WANG Ziyi

Date: 19 5月 2022

ENSG00000233369

1 Isoform Switch

TableFilter v0.7.3

2 Differential Exon Usage

TableFilter v0.7.3