ENSG00000232104

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000423112 ENSG00000232104 HEK293_OSMI2_6hA HEK293_TMG_6hB RFX3-DT lncRNA lncRNA 0.4339681 0.3701578 0.3751586 0.07147443 0.08284073 0.01885412 0.08080996 0.02853445 0.00000000 0.02853445 0.00000000 -1.94614874 0.14385833 0.09723333 0.00000000 -0.09723333 0.87484739 0.04468046   FALSE
ENST00000427722 ENSG00000232104 HEK293_OSMI2_6hA HEK293_TMG_6hB RFX3-DT lncRNA lncRNA 0.4339681 0.3701578 0.3751586 0.07147443 0.08284073 0.01885412 0.14443160 0.16086304 0.12001971 0.03255477 0.03705851 -0.39410995 0.31302917 0.44210000 0.30356667 -0.13853333 0.79971465 0.04468046   FALSE
ENST00000457566 ENSG00000232104 HEK293_OSMI2_6hA HEK293_TMG_6hB RFX3-DT lncRNA lncRNA 0.4339681 0.3701578 0.3751586 0.07147443 0.08284073 0.01885412 0.03031644 0.12865545 0.00000000 0.06940503 0.00000000 -3.79343240 0.05746667 0.31683333 0.00000000 -0.31683333 0.31213591 0.04468046   FALSE
ENST00000691026 ENSG00000232104 HEK293_OSMI2_6hA HEK293_TMG_6hB RFX3-DT lncRNA lncRNA 0.4339681 0.3701578 0.3751586 0.07147443 0.08284073 0.01885412 0.03609992 0.03316162 0.03072417 0.01870761 0.03072417 -0.08386372 0.13974583 0.08153333 0.06873333 -0.01280000 0.99446151 0.04468046   FALSE
ENST00000691391 ENSG00000232104 HEK293_OSMI2_6hA HEK293_TMG_6hB RFX3-DT lncRNA lncRNA 0.4339681 0.3701578 0.3751586 0.07147443 0.08284073 0.01885412 0.14231021 0.01894325 0.22441469 0.01894325 0.05095343 3.01776395 0.34591250 0.06230000 0.62770000 0.56540000 0.04468046 0.04468046   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_6hB HEK293_OSMI2_6hA log2fold_HEK293_OSMI2_6hA_HEK293_TMG_6hB
ENSG00000232104 E001 0.4466850 0.03629253 0.0525215123   9 3526466 3526499 34 + 0.300 0.000 -12.999
ENSG00000232104 E002 2.4209419 0.01177630 0.0002451104 0.003165429 9 3526500 3526722 223 + 0.726 0.211 -2.782
ENSG00000232104 E003 1.3308071 0.02258943 0.0707093060   9 3526723 3526777 55 + 0.476 0.211 -1.669
ENSG00000232104 E004 0.3032425 0.02744240 0.2865626893   9 3546778 3546912 135 + 0.000 0.211 12.218
ENSG00000232104 E005 0.0000000       9 3555636 3556308 673 +      
ENSG00000232104 E006 0.3032425 0.02744240 0.2865626893   9 3568794 3568889 96 + 0.000 0.211 12.218
ENSG00000232104 E007 0.3032425 0.02744240 0.2865626893   9 3602523 3602584 62 + 0.000 0.211 12.218
ENSG00000232104 E008 0.4397201 0.04800267 0.7500109709   9 3602585 3603051 467 + 0.125 0.210 0.906
ENSG00000232104 E009 0.1723744 0.04354786 0.6166623462   9 3606693 3606738 46 + 0.000 0.119 11.222
ENSG00000232104 E010 0.8507255 0.02630158 0.0327620648   9 3668086 3668164 79 + 0.000 0.410 13.545
ENSG00000232104 E011 1.2185795 0.01713264 0.0551085556   9 3668165 3668408 244 + 0.125 0.504 2.720
ENSG00000232104 E012 0.4341107 0.02444117 0.1361017765   9 3671474 3671476 3 + 0.000 0.287 12.801
ENSG00000232104 E013 1.3798075 0.01637263 0.0311390679   9 3671477 3671634 158 + 0.125 0.544 2.913
ENSG00000232104 E014 0.8619444 0.02376858 0.8659777234   9 3671635 3671645 11 + 0.221 0.288 0.502
ENSG00000232104 E015 0.0000000       9 3671646 3671646 1 +      
ENSG00000232104 E016 2.0466027 0.01317416 0.8484813832 0.924076549 9 3674411 3674648 238 + 0.476 0.504 0.139
ENSG00000232104 E017 1.7135479 0.02224344 0.9075070678 0.955897136 9 3690837 3690959 123 + 0.424 0.460 0.186
ENSG00000232104 E018 1.7606636 0.01876602 0.4623872512 0.674791089 9 3691504 3691814 311 + 0.475 0.410 -0.340