ENSG00000230487

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000437621 ENSG00000230487 HEK293_OSMI2_6hA HEK293_TMG_6hB PSMG3-AS1 lncRNA lncRNA 5.788649 8.051062 2.539371 0.9771312 0.3606629 -1.660829 1.5572758 2.3990747 0.7748835 0.12316004 0.07845547 -1.6179288 0.28424167 0.3033333 0.3094000 0.006066667 1.00000000 0.03063705 FALSE  
ENST00000457484 ENSG00000230487 HEK293_OSMI2_6hA HEK293_TMG_6hB PSMG3-AS1 lncRNA lncRNA 5.788649 8.051062 2.539371 0.9771312 0.3606629 -1.660829 0.6333214 0.9087019 0.3243829 0.06574941 0.10388989 -1.4580956 0.11310000 0.1166667 0.1312667 0.014600000 0.99549228 0.03063705 FALSE  
ENST00000524978 ENSG00000230487 HEK293_OSMI2_6hA HEK293_TMG_6hB PSMG3-AS1 lncRNA lncRNA 5.788649 8.051062 2.539371 0.9771312 0.3606629 -1.660829 0.1667041 0.3902091 0.0000000 0.10274997 0.00000000 -5.3226820 0.02446667 0.0519000 0.0000000 -0.051900000 0.03063705 0.03063705    
ENST00000532358 ENSG00000230487 HEK293_OSMI2_6hA HEK293_TMG_6hB PSMG3-AS1 lncRNA lncRNA 5.788649 8.051062 2.539371 0.9771312 0.3606629 -1.660829 0.9712915 1.1582267 0.7578165 0.31729987 0.23449711 -0.6054867 0.18267500 0.1400000 0.3201000 0.180100000 0.53082964 0.03063705    
ENST00000651857 ENSG00000230487 HEK293_OSMI2_6hA HEK293_TMG_6hB PSMG3-AS1 lncRNA lncRNA 5.788649 8.051062 2.539371 0.9771312 0.3606629 -1.660829 2.2107135 2.9268232 0.4673167 0.71315751 0.46731672 -2.6212376 0.34590833 0.3531000 0.1462333 -0.206866667 0.38252716 0.03063705    
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_6hB HEK293_OSMI2_6hA log2fold_HEK293_OSMI2_6hA_HEK293_TMG_6hB
ENSG00000230487 E001 0.0000000       7 1570073 1570079 7 +      
ENSG00000230487 E002 0.3641499 0.0305306222 0.36410750   7 1570080 1570088 9 + 0.205 0.069 -1.802
ENSG00000230487 E003 4.9806852 0.0052336092 0.20212680 0.43227105 7 1570089 1570115 27 + 0.847 0.665 -0.736
ENSG00000230487 E004 9.3123110 0.0032952474 0.50955673 0.70764568 7 1570116 1570134 19 + 1.002 0.925 -0.287
ENSG00000230487 E005 9.8486476 0.0031859630 0.65630622 0.80753773 7 1570135 1570141 7 + 1.002 0.951 -0.189
ENSG00000230487 E006 14.3657044 0.0034351810 0.94093921 0.97272313 7 1570142 1570168 27 + 1.116 1.110 -0.021
ENSG00000230487 E007 21.0009124 0.0017613512 0.80346323 0.89829877 7 1570169 1570233 65 + 1.281 1.261 -0.069
ENSG00000230487 E008 21.7155698 0.0016701926 0.22508639 0.45952365 7 1570234 1570279 46 + 1.190 1.301 0.390
ENSG00000230487 E009 16.3104834 0.0024098138 0.70165216 0.83664515 7 1570280 1570533 254 + 1.135 1.175 0.142
ENSG00000230487 E010 38.6025797 0.0031964812 0.92245071 0.96352845 7 1574715 1574863 149 + 1.526 1.521 -0.017
ENSG00000230487 E011 35.1026442 0.0104818201 0.16007087 0.37690250 7 1575787 1575888 102 + 1.564 1.457 -0.367
ENSG00000230487 E012 1.1124618 0.0147444798 0.12463809   7 1575889 1576062 174 + 0.000 0.344 10.192
ENSG00000230487 E013 17.0529575 0.0193908547 0.70256120 0.83718828 7 1579287 1579404 118 + 1.152 1.199 0.165
ENSG00000230487 E014 6.1788072 0.0317825052 0.79269703 0.89199557 7 1579405 1579485 81 + 0.764 0.810 0.184
ENSG00000230487 E015 8.2021823 0.0128219549 0.06745265 0.21934800 7 1583162 1583269 108 + 1.051 0.817 -0.882
ENSG00000230487 E016 72.2534573 0.0023073840 0.03930544 0.15299381 7 1584384 1585617 1234 + 1.855 1.756 -0.333
ENSG00000230487 E017 107.5566431 0.0008288948 0.56986566 0.75019376 7 1585618 1587820 2203 + 1.935 1.957 0.076
ENSG00000230487 E018 133.1802911 0.0019612241 0.01795946 0.08890107 7 1587821 1589626 1806 + 1.978 2.066 0.294