ENSG00000215252

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000342314 ENSG00000215252 HEK293_OSMI2_6hA HEK293_TMG_6hB GOLGA8B protein_coding protein_coding 7.435167 10.64795 8.226798 4.759117 0.9473485 -0.3717741 1.6355698 2.2147258 1.14241289 0.3926641 0.33385979 -0.9489698 0.26759583 0.26796667 0.132833333 -0.1351333 0.608441366 0.007933381 FALSE TRUE
ENST00000484716 ENSG00000215252 HEK293_OSMI2_6hA HEK293_TMG_6hB GOLGA8B protein_coding retained_intron 7.435167 10.64795 8.226798 4.759117 0.9473485 -0.3717741 0.8906621 1.1931125 1.63707213 1.1931125 0.30992827 0.4531322 0.11207500 0.05920000 0.196466667 0.1372667 0.306158344 0.007933381 FALSE TRUE
ENST00000562282 ENSG00000215252 HEK293_OSMI2_6hA HEK293_TMG_6hB GOLGA8B protein_coding processed_transcript 7.435167 10.64795 8.226798 4.759117 0.9473485 -0.3717741 0.7378426 1.3835194 0.96468716 0.7138586 0.63043754 -0.5157219 0.09851250 0.14683333 0.102833333 -0.0440000 0.989560944 0.007933381   FALSE
ENST00000566091 ENSG00000215252 HEK293_OSMI2_6hA HEK293_TMG_6hB GOLGA8B protein_coding processed_transcript 7.435167 10.64795 8.226798 4.759117 0.9473485 -0.3717741 0.3863544 0.6192803 1.63658383 0.6192803 0.33561418 1.3877012 0.04074583 0.03073333 0.199266667 0.1685333 0.181257327 0.007933381   FALSE
ENST00000569100 ENSG00000215252 HEK293_OSMI2_6hA HEK293_TMG_6hB GOLGA8B protein_coding retained_intron 7.435167 10.64795 8.226798 4.759117 0.9473485 -0.3717741 1.1528603 1.6389163 0.07783551 0.8433024 0.07783551 -4.2305701 0.12861667 0.14696667 0.007966667 -0.1390000 0.007933381 0.007933381 FALSE TRUE
ENST00000683415 ENSG00000215252 HEK293_OSMI2_6hA HEK293_TMG_6hB GOLGA8B protein_coding protein_coding 7.435167 10.64795 8.226798 4.759117 0.9473485 -0.3717741 1.9376432 2.3700199 1.64703877 1.3122658 0.15348869 -0.5223663 0.26311667 0.20626667 0.202766667 -0.0035000 0.968926037 0.007933381 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

No results under this category.

Splicing

All exons whithin this gene region are shown and numbering below.

No results under this category.

Transcripts

All isoforms whithin this gene region are shown below.

No results under this category.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_6hB HEK293_OSMI2_6hA log2fold_HEK293_OSMI2_6hA_HEK293_TMG_6hB
ENSG00000215252 E001 3.6522922 0.031385250 0.67251459 0.81790115 15 34525095 34525206 112 - 0.568 0.665 0.427
ENSG00000215252 E002 6.5131507 0.167472348 0.51502609 0.71166213 15 34525207 34525281 75 - 0.675 0.882 0.828
ENSG00000215252 E003 55.5739659 0.097473091 0.04274770 0.16190604 15 34525282 34525653 372 - 1.509 1.748 0.814
ENSG00000215252 E004 251.8353064 1.071315747 0.41245892 0.63795013 15 34525654 34526958 1305 - 2.245 2.376 0.437
ENSG00000215252 E005 114.9021134 0.472045238 0.39102694 0.62116242 15 34526959 34527335 377 - 1.938 2.029 0.304
ENSG00000215252 E006 43.7220817 0.142872628 0.64992074 0.80351402 15 34527336 34527495 160 - 1.591 1.597 0.020
ENSG00000215252 E007 9.1882575 0.004637362 0.99821790 1.00000000 15 34527496 34527511 16 - 0.933 0.959 0.101
ENSG00000215252 E008 6.5038871 0.008765132 0.31085363 0.55131533 15 34527512 34527527 16 - 0.679 0.857 0.711
ENSG00000215252 E009 4.2950314 0.009074152 0.26435897 0.50357520 15 34527528 34527528 1 - 0.500 0.720 0.974
ENSG00000215252 E010 4.1336157 0.009936640 0.12558489 0.32476324 15 34527529 34527530 2 - 0.418 0.720 1.390
ENSG00000215252 E011 5.0433433 0.006236546 0.03650355 0.14560754 15 34527531 34527573 43 - 0.419 0.806 1.735
ENSG00000215252 E012 3.0286010 0.009191339 0.14915118 0.36101681 15 34527574 34527607 34 - 0.318 0.612 1.514
ENSG00000215252 E013 3.0286010 0.009191339 0.14915118 0.36101681 15 34527608 34527834 227 - 0.318 0.612 1.514
ENSG00000215252 E014 0.0000000       15 34527922 34527924 3 -      
ENSG00000215252 E015 0.3150090 0.027442404 0.41445376   15 34527925 34528077 153 - 0.188 0.077 -1.487
ENSG00000215252 E016 0.0000000       15 34528189 34528289 101 -      
ENSG00000215252 E017 0.0000000       15 34528372 34528472 101 -      
ENSG00000215252 E018 0.0000000       15 34528607 34528747 141 -      
ENSG00000215252 E019 0.0000000       15 34528748 34528750 3 -      
ENSG00000215252 E020 0.0000000       15 34529018 34529274 257 -      
ENSG00000215252 E021 0.0000000       15 34529662 34529749 88 -      
ENSG00000215252 E022 0.0000000       15 34529967 34530074 108 -      
ENSG00000215252 E023 0.0000000       15 34530182 34530268 87 -      
ENSG00000215252 E024 0.1426347 0.033639497 0.15858438   15 34531269 34531378 110 - 0.188 0.000 -36.484
ENSG00000215252 E025 1.2967903 0.014115461 1.00000000   15 34531475 34531559 85 - 0.318 0.334 0.097
ENSG00000215252 E026 1.5101233 0.276777798 0.44647115 0.66308056 15 34531648 34531695 48 - 0.423 0.336 -0.501
ENSG00000215252 E027 0.1723744 0.029788854 1.00000000   15 34531961 34531999 39 - 0.000 0.077 33.472
ENSG00000215252 E028 0.3751086 0.032883619 0.80235646   15 34532846 34532962 117 - 0.000 0.142 34.476
ENSG00000215252 E029 0.2027342 0.546266641 1.00000000   15 34532963 34533109 147 - 0.000 0.079 33.523
ENSG00000215252 E030 0.3926045 0.846657287 0.76877454   15 34533110 34533145 36 - 0.000 0.183 34.920
ENSG00000215252 E031 0.0000000       15 34533146 34533185 40 -      
ENSG00000215252 E032 0.3926045 0.846657287 0.76877454   15 34533186 34533346 161 - 0.000 0.183 34.920
ENSG00000215252 E033 0.0000000       15 34533347 34533484 138 -      
ENSG00000215252 E034 0.0000000       15 34533485 34534053 569 -      
ENSG00000215252 E035 0.0000000       15 34534054 34534173 120 -      
ENSG00000215252 E036 0.0000000       15 34535865 34535989 125 -      
ENSG00000215252 E037 0.0000000       15 34535990 34536010 21 -      
ENSG00000215252 E038 0.1723744 0.029788854 1.00000000   15 34537344 34537647 304 - 0.000 0.077 33.472
ENSG00000215252 E039 13.4986696 0.144181367 0.04993741 0.17954653 15 34544858 34544953 96 - 1.310 1.009 -1.077
ENSG00000215252 E040 14.7893029 0.149494249 0.05979347 0.20232134 15 34545378 34545387 10 - 1.334 1.055 -0.991
ENSG00000215252 E041 15.5855382 0.165030495 0.06799741 0.22057466 15 34545388 34545426 39 - 1.355 1.076 -0.989
ENSG00000215252 E042 11.3262607 0.227251722 0.05743054 0.19702684 15 34546935 34546982 48 - 1.266 0.919 -1.260
ENSG00000215252 E043 9.5186536 0.218991146 0.24096620 0.47766550 15 34551138 34551190 53 - 1.113 0.907 -0.758
ENSG00000215252 E044 8.2772379 0.006829885 0.41447051 0.63941920 15 34551191 34551276 86 - 0.807 0.949 0.547
ENSG00000215252 E045 1.3033096 0.597534375 0.68366949   15 34552268 34552398 131 - 0.191 0.353 1.187
ENSG00000215252 E046 16.2755647 0.076086940 0.01603420 0.08193688 15 34552895 34552972 78 - 1.353 1.101 -0.891
ENSG00000215252 E047 14.9496997 0.127554594 0.02367185 0.10807389 15 34552973 34553091 119 - 1.333 1.056 -0.984
ENSG00000215252 E048 15.1813565 0.178657729 0.14279563 0.35164267 15 34553745 34553956 212 - 1.238 1.121 -0.418
ENSG00000215252 E049 0.0000000       15 34565890 34566473 584 -      
ENSG00000215252 E050 0.1723744 0.029788854 1.00000000   15 34574825 34574914 90 - 0.000 0.077 33.472
ENSG00000215252 E051 0.5283420 0.828014047 0.29702074   15 34581466 34581499 34 - 0.328 0.078 -2.524
ENSG00000215252 E052 1.8417005 0.524818392 0.41994350 0.64361513 15 34582750 34582860 111 - 0.507 0.375 -0.694
ENSG00000215252 E053 6.6591045 0.302305471 0.46015604 0.67322306 15 34583516 34583678 163 - 0.851 0.825 -0.102
ENSG00000215252 E054 1.3376315 0.054501875 0.62278953   15 34588391 34588503 113 - 0.417 0.332 -0.491