ENSG00000203880

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000308824 ENSG00000203880 HEK293_OSMI2_6hA HEK293_TMG_6hB PCMTD2 protein_coding protein_coding 11.72071 6.918204 14.66246 0.7155797 1.405469 1.082557 5.2190575 2.5670725 7.6843426 0.3805864 0.81750724 1.5780649 0.43798750 0.36916667 0.541200000 0.17203333 0.595043344 0.004206045 FALSE TRUE
ENST00000609297 ENSG00000203880 HEK293_OSMI2_6hA HEK293_TMG_6hB PCMTD2 protein_coding processed_transcript 11.72071 6.918204 14.66246 0.7155797 1.405469 1.082557 1.5337875 0.3032796 1.5819505 0.3032796 0.79214263 2.3452728 0.08903333 0.03633333 0.098733333 0.06240000 0.738619853 0.004206045   FALSE
ENST00000609818 ENSG00000203880 HEK293_OSMI2_6hA HEK293_TMG_6hB PCMTD2 protein_coding protein_coding 11.72071 6.918204 14.66246 0.7155797 1.405469 1.082557 0.4889118 0.8313978 0.1013233 0.2128640 0.05385871 -2.9180326 0.07093750 0.12426667 0.007566667 -0.11670000 0.004206045 0.004206045 FALSE FALSE
ENST00000610074 ENSG00000203880 HEK293_OSMI2_6hA HEK293_TMG_6hB PCMTD2 protein_coding protein_coding 11.72071 6.918204 14.66246 0.7155797 1.405469 1.082557 1.0770763 1.1060576 1.2019305 0.3717481 0.60779404 0.1188956 0.09155417 0.15336667 0.074800000 -0.07856667 0.755593384 0.004206045 FALSE FALSE
MSTRG.21027.8 ENSG00000203880 HEK293_OSMI2_6hA HEK293_TMG_6hB PCMTD2 protein_coding   11.72071 6.918204 14.66246 0.7155797 1.405469 1.082557 1.3269888 0.7639732 1.5265046 0.1471707 0.20490470 0.9892965 0.12073750 0.11670000 0.103366667 -0.01333333 0.988387866 0.004206045 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_6hB HEK293_OSMI2_6hA log2fold_HEK293_OSMI2_6hA_HEK293_TMG_6hB
ENSG00000203880 E001 0.1426347 0.0311077380 0.826076581   20 64255695 64255740 46 + 0.090 0.000 -19.450
ENSG00000203880 E002 0.4349185 0.0217681645 0.950687238   20 64255741 64255746 6 + 0.164 0.162 -0.028
ENSG00000203880 E003 1.0312526 0.0776004295 0.696551264   20 64255747 64255747 1 + 0.332 0.278 -0.358
ENSG00000203880 E004 1.1926683 0.1950714004 0.593184597   20 64255748 64255748 1 + 0.375 0.275 -0.637
ENSG00000203880 E005 1.3353030 0.1312583922 0.450376273   20 64255749 64255752 4 + 0.415 0.276 -0.846
ENSG00000203880 E006 1.6088058 0.2926274780 0.632371626 0.79188521 20 64255753 64255753 1 + 0.448 0.361 -0.481
ENSG00000203880 E007 1.6088058 0.2926274780 0.632371626 0.79188521 20 64255754 64255755 2 + 0.448 0.361 -0.481
ENSG00000203880 E008 8.1657668 0.3649807950 0.983770169 0.99370588 20 64255756 64255843 88 + 0.971 0.899 -0.269
ENSG00000203880 E009 8.5565201 0.3679403009 0.964063018 0.98390650 20 64255844 64255870 27 + 0.994 0.902 -0.344
ENSG00000203880 E010 2.5956287 0.0738131147 0.314023176 0.55425089 20 64255871 64255924 54 + 0.451 0.669 1.007
ENSG00000203880 E011 11.8404631 0.3130345171 0.401470619 0.62952619 20 64256106 64256196 91 + 1.030 1.187 0.569
ENSG00000203880 E012 12.4061869 0.4353732490 0.795742280 0.89390006 20 64256550 64256585 36 + 1.124 1.077 -0.170
ENSG00000203880 E013 28.2170899 0.6743685514 0.672343883 0.81780482 20 64256586 64256901 316 + 1.446 1.441 -0.017
ENSG00000203880 E014 20.8632280 0.5200387179 0.408739221 0.63507110 20 64256902 64257051 150 + 1.254 1.422 0.585
ENSG00000203880 E015 14.3759875 0.3296614099 0.158193666 0.37407991 20 64258767 64258882 116 + 1.026 1.351 1.156
ENSG00000203880 E016 7.7876758 0.0674334446 0.016302899 0.08290159 20 64259831 64259941 111 + 0.743 1.151 1.538
ENSG00000203880 E017 39.6227452 0.7344965331 0.429254129 0.65046734 20 64259942 64260084 143 + 1.523 1.689 0.569
ENSG00000203880 E018 30.9253324 0.6962893949 0.532729870 0.72404210 20 64260085 64260178 94 + 1.444 1.549 0.361
ENSG00000203880 E019 36.8353771 0.7404149640 0.561645080 0.74442854 20 64260179 64260272 94 + 1.530 1.603 0.249
ENSG00000203880 E020 2.7539535 0.0689691131 0.074095881 0.23291411 20 64262528 64262687 160 + 0.378 0.748 1.733
ENSG00000203880 E021 2.1770384 0.0102486746 0.122022188 0.31906131 20 64262771 64262950 180 + 0.377 0.664 1.386
ENSG00000203880 E022 53.1021967 0.0227941229 0.431394118 0.65223657 20 64264429 64264531 103 + 1.725 1.693 -0.110
ENSG00000203880 E023 86.6735875 0.0004994439 0.002451215 0.02001599 20 64265258 64265429 172 + 1.947 1.873 -0.247
ENSG00000203880 E024 4.5134039 0.0065073225 0.738961886 0.85977476 20 64265512 64265613 102 + 0.691 0.776 0.347
ENSG00000203880 E025 58.2079649 0.0227215180 0.207531493 0.43885124 20 64267887 64267967 81 + 1.766 1.712 -0.183
ENSG00000203880 E026 48.8913317 0.0399803932 0.395980841 0.62517588 20 64267968 64268010 43 + 1.687 1.648 -0.132
ENSG00000203880 E027 3.9788050 0.3623480278 0.154602829 0.36887079 20 64271482 64272230 749 + 0.374 0.973 2.620
ENSG00000203880 E028 627.2871728 0.0628755466 0.985337749 0.99443755 20 64273221 64276226 3006 + 2.754 2.814 0.202
ENSG00000203880 E029 0.3503582 0.0306940224 0.681062750   20 64287679 64287821 143 + 0.090 0.162 0.973