ENSG00000197766

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000695943 ENSG00000197766 HEK293_OSMI2_6hA HEK293_TMG_6hB CFD protein_coding protein_coding 23.23025 31.77206 9.289186 4.486406 0.5336512 -1.773036 4.426469 5.842131 1.8313217 0.8730061 0.3035088 -1.668221 0.19608333 0.18366667 0.20016667 0.01650000 9.733125e-01 7.351688e-06 FALSE  
ENST00000695946 ENSG00000197766 HEK293_OSMI2_6hA HEK293_TMG_6hB CFD protein_coding protein_coding 23.23025 31.77206 9.289186 4.486406 0.5336512 -1.773036 1.203113 1.034560 2.8341763 1.0345599 0.5750322 1.445116 0.08745417 0.04233333 0.30183333 0.25950000 1.295292e-01 7.351688e-06 FALSE  
MSTRG.16014.10 ENSG00000197766 HEK293_OSMI2_6hA HEK293_TMG_6hB CFD protein_coding   23.23025 31.77206 9.289186 4.486406 0.5336512 -1.773036 1.738640 2.531172 1.0176273 0.2710702 0.4371327 -1.306177 0.08100000 0.08070000 0.10793333 0.02723333 9.936870e-01 7.351688e-06 FALSE  
MSTRG.16014.11 ENSG00000197766 HEK293_OSMI2_6hA HEK293_TMG_6hB CFD protein_coding   23.23025 31.77206 9.289186 4.486406 0.5336512 -1.773036 3.509927 5.139977 0.7305427 1.2310273 0.3978240 -2.797911 0.14477083 0.15713333 0.07973333 -0.07740000 5.104928e-01 7.351688e-06    
MSTRG.16014.7 ENSG00000197766 HEK293_OSMI2_6hA HEK293_TMG_6hB CFD protein_coding   23.23025 31.77206 9.289186 4.486406 0.5336512 -1.773036 1.540326 2.108635 0.0000000 0.4518055 0.0000000 -7.726991 0.05700833 0.06970000 0.00000000 -0.06970000 7.351688e-06 7.351688e-06 FALSE  
MSTRG.16014.9 ENSG00000197766 HEK293_OSMI2_6hA HEK293_TMG_6hB CFD protein_coding   23.23025 31.77206 9.289186 4.486406 0.5336512 -1.773036 10.435490 14.605091 2.8755176 2.8923325 0.1370249 -2.340557 0.41992500 0.45186667 0.31030000 -0.14156667 1.438900e-01 7.351688e-06 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_6hB HEK293_OSMI2_6hA log2fold_HEK293_OSMI2_6hA_HEK293_TMG_6hB
ENSG00000197766 E001 0.0000000       19 859453 859516 64 +      
ENSG00000197766 E002 0.0000000       19 859517 859532 16 +      
ENSG00000197766 E003 0.1308682 0.0326491905 1.0000000000   19 859664 859744 81 + 0.000 0.052 6.827
ENSG00000197766 E004 0.0000000       19 859745 859765 21 +      
ENSG00000197766 E005 0.1723744 0.0399238927 1.0000000000   19 859766 859835 70 + 0.000 0.052 6.830
ENSG00000197766 E006 0.2735028 0.0274424043 0.2197756728   19 860594 860616 23 + 0.259 0.052 -2.679
ENSG00000197766 E007 1.9397970 0.0123919110 0.4101594355 0.636113410 19 860617 860647 31 + 0.259 0.402 0.902
ENSG00000197766 E008 4.0182668 0.0105037510 0.0704958847 0.225713096 19 860648 860655 8 + 0.259 0.608 1.904
ENSG00000197766 E009 10.9729623 0.0037755079 0.0127021237 0.069246983 19 860656 860661 6 + 0.630 0.973 1.361
ENSG00000197766 E010 79.1089633 0.0005545300 0.0003404076 0.004143449 19 860662 860773 112 + 1.621 1.763 0.480
ENSG00000197766 E011 14.5739420 0.0026923482 0.1233985836 0.321139360 19 860774 860860 87 + 0.921 1.058 0.507
ENSG00000197766 E012 93.2656333 0.0041552868 0.0611137819 0.205267415 19 860861 860909 49 + 1.776 1.817 0.136
ENSG00000197766 E013 148.3980002 0.0009771372 0.1219777801 0.319015486 19 860910 861005 96 + 2.020 2.011 -0.027
ENSG00000197766 E014 121.9202520 0.0019611686 0.9251628246 0.964838014 19 861699 861749 51 + 1.985 1.919 -0.219
ENSG00000197766 E015 209.5509702 0.0038938975 0.0074667048 0.046866433 19 861750 861956 207 + 2.124 2.165 0.135
ENSG00000197766 E016 213.2881835 0.0311300176 0.1223603295 0.319518994 19 863092 865008 1917 + 2.331 2.131 -0.671
ENSG00000197766 E017 42.0430799 0.5447808751 0.9677875697 0.985764599 19 865891 866569 679 + 1.701 1.421 -0.956
ENSG00000197766 E018 106.8479054 0.1046522677 0.3305302382 0.569482457 19 867429 867950 522 + 2.078 1.823 -0.857
ENSG00000197766 E019 73.1538061 0.0119455333 0.9410838352 0.972783856 19 868577 868774 198 + 1.781 1.694 -0.293