ENSG00000197467

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000357811 ENSG00000197467 HEK293_OSMI2_6hA HEK293_TMG_6hB COL13A1 protein_coding protein_coding 2.80926 2.934856 1.753569 0.03071705 0.1265902 -0.7396992 0.12332848 0.2254584 0.02535393 0.09826321 0.02535393 -2.73552967 0.04307500 0.07616667 0.01300000 -0.063166667 4.116372e-01 3.181594e-05 FALSE TRUE
ENST00000683952 ENSG00000197467 HEK293_OSMI2_6hA HEK293_TMG_6hB COL13A1 protein_coding processed_transcript 2.80926 2.934856 1.753569 0.03071705 0.1265902 -0.7396992 0.02265533 0.0000000 0.18124261 0.00000000 0.18124261 4.25733207 0.01265417 0.00000000 0.10123333 0.101233333 8.019956e-01 3.181594e-05 FALSE TRUE
MSTRG.4109.10 ENSG00000197467 HEK293_OSMI2_6hA HEK293_TMG_6hB COL13A1 protein_coding   2.80926 2.934856 1.753569 0.03071705 0.1265902 -0.7396992 0.16392976 0.0671054 0.02815378 0.06710540 0.02815378 -1.01500582 0.05623750 0.02246667 0.01853333 -0.003933333 1.000000e+00 3.181594e-05 FALSE TRUE
MSTRG.4109.24 ENSG00000197467 HEK293_OSMI2_6hA HEK293_TMG_6hB COL13A1 protein_coding   2.80926 2.934856 1.753569 0.03071705 0.1265902 -0.7396992 0.25451340 0.9596098 0.00000000 0.25459069 0.00000000 -6.59933234 0.09052083 0.32790000 0.00000000 -0.327900000 3.181594e-05 3.181594e-05 FALSE TRUE
MSTRG.4109.27 ENSG00000197467 HEK293_OSMI2_6hA HEK293_TMG_6hB COL13A1 protein_coding   2.80926 2.934856 1.753569 0.03071705 0.1265902 -0.7396992 0.37986410 0.4716483 0.46184224 0.17098413 0.10377533 -0.02967534 0.13435417 0.15960000 0.25776667 0.098166667 6.784697e-01 3.181594e-05 FALSE TRUE
MSTRG.4109.4 ENSG00000197467 HEK293_OSMI2_6hA HEK293_TMG_6hB COL13A1 protein_coding   2.80926 2.934856 1.753569 0.03071705 0.1265902 -0.7396992 0.94412569 0.6046476 0.63017246 0.10061467 0.10197411 0.05870116 0.33806250 0.20636667 0.37073333 0.164366667 5.293941e-01 3.181594e-05 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_6hB HEK293_OSMI2_6hA log2fold_HEK293_OSMI2_6hA_HEK293_TMG_6hB
ENSG00000197467 E001 1.3865847 0.019334684 0.52976827   10 69801880 69801905 26 + 0.288 0.405 0.710
ENSG00000197467 E002 1.3865847 0.019334684 0.52976827   10 69801906 69801909 4 + 0.288 0.405 0.710
ENSG00000197467 E003 3.5928676 0.007598373 0.99336582 0.99833920 10 69801910 69801930 21 + 0.634 0.635 0.004
ENSG00000197467 E004 3.5928676 0.007598373 0.99336582 0.99833920 10 69801931 69801931 1 + 0.634 0.635 0.004
ENSG00000197467 E005 8.7790138 0.006745580 0.45177169 0.66695278 10 69801932 69802048 117 + 1.018 0.930 -0.329
ENSG00000197467 E006 8.0618467 0.003873084 0.47964000 0.68687346 10 69802049 69802070 22 + 0.977 0.895 -0.311
ENSG00000197467 E007 6.7649838 0.004564184 0.76348124 0.87476420 10 69802071 69802072 2 + 0.881 0.843 -0.146
ENSG00000197467 E008 9.3232902 0.004223525 0.38378192 0.61539679 10 69802073 69802117 45 + 1.038 0.941 -0.358
ENSG00000197467 E009 8.1223942 0.004298453 0.11499779 0.30747976 10 69802118 69802147 30 + 1.038 0.856 -0.680
ENSG00000197467 E010 12.8553515 0.003203553 0.01274790 0.06942747 10 69802148 69802413 266 + 1.255 1.021 -0.841
ENSG00000197467 E011 2.5273966 0.021783196 0.33000069 0.56895134 10 69802414 69802423 10 + 0.634 0.474 -0.740
ENSG00000197467 E012 2.9081146 0.009408430 0.27046733 0.51044723 10 69802424 69802456 33 + 0.679 0.506 -0.776
ENSG00000197467 E013 5.0616724 0.005879626 0.66964690 0.81606158 10 69802457 69802546 90 + 0.792 0.734 -0.234
ENSG00000197467 E014 3.2005707 0.007105874 0.86319360 0.93211647 10 69802547 69802551 5 + 0.583 0.611 0.126
ENSG00000197467 E015 4.9508728 0.005519525 0.74537949 0.86393287 10 69802552 69802591 40 + 0.720 0.767 0.193
ENSG00000197467 E016 4.8008638 0.005714674 0.57669123 0.75489995 10 69802592 69802619 28 + 0.792 0.715 -0.309
ENSG00000197467 E017 9.0224277 0.003678545 0.42874061 0.65014168 10 69802620 69802717 98 + 0.907 1.002 0.353
ENSG00000197467 E018 10.7716145 0.002965326 0.29318887 0.53390270 10 69822369 69822438 70 + 0.955 1.072 0.431
ENSG00000197467 E019 0.0000000       10 69852054 69852329 276 +      
ENSG00000197467 E020 7.8775654 0.003713599 0.26813303 0.50780247 10 69867798 69867805 8 + 0.823 0.962 0.528
ENSG00000197467 E021 3.2711516 0.009440103 0.75202767 0.86795332 10 69872184 69872210 27 + 0.583 0.634 0.224
ENSG00000197467 E022 0.1614157 0.036910145 0.22676416   10 69872211 69873562 1352 + 0.168 0.000 -12.435
ENSG00000197467 E023 1.4869731 0.013777613 0.44357097 0.66110733 10 69875128 69875136 9 + 0.460 0.323 -0.770
ENSG00000197467 E024 1.6593475 0.015836003 0.60300095 0.77224993 10 69875137 69875163 27 + 0.460 0.367 -0.506
ENSG00000197467 E025 0.0000000       10 69877296 69877603 308 +      
ENSG00000197467 E026 1.6706863 0.048338480 0.75144749 0.86767356 10 69878039 69878065 27 + 0.460 0.403 -0.305
ENSG00000197467 E027 0.1723744 0.032480055 1.00000000   10 69879403 69879427 25 + 0.000 0.087 10.209
ENSG00000197467 E028 0.1308682 0.031434764 1.00000000   10 69880414 69880502 89 + 0.000 0.086 10.204
ENSG00000197467 E029 3.2011231 0.113470311 0.32937285 0.56839355 10 69880503 69880553 51 + 0.458 0.667 0.962
ENSG00000197467 E030 9.8435385 0.003346872 0.56319876 0.74554208 10 69887456 69887491 36 + 0.955 1.021 0.243
ENSG00000197467 E031 10.2879582 0.003306689 0.86323639 0.93214896 10 69888304 69888330 27 + 1.038 1.020 -0.064
ENSG00000197467 E032 10.2701025 0.003362424 0.43614516 0.65591718 10 69889414 69889422 9 + 1.074 0.992 -0.299
ENSG00000197467 E033 10.3136339 0.003450383 0.60304917 0.77228257 10 69889423 69889440 18 + 1.056 1.002 -0.199
ENSG00000197467 E034 0.0000000       10 69891441 69891509 69 +      
ENSG00000197467 E035 11.4855456 0.007937983 0.40126822 0.62935409 10 69894552 69894578 27 + 1.123 1.038 -0.310
ENSG00000197467 E036 9.0504751 0.029017701 0.56487775 0.74669371 10 69894675 69894694 20 + 1.021 0.949 -0.268
ENSG00000197467 E037 7.3857582 0.005244602 0.82477932 0.91078244 10 69894695 69894701 7 + 0.908 0.882 -0.098
ENSG00000197467 E038 8.7506132 0.008433419 0.42818832 0.64958260 10 69895550 69895576 27 + 1.019 0.929 -0.334
ENSG00000197467 E039 0.3751086 0.024787034 0.50009022   10 69897475 69897531 57 + 0.000 0.159 11.211
ENSG00000197467 E040 1.3502555 0.016448943 0.91514681   10 69898697 69898762 66 + 0.383 0.365 -0.102
ENSG00000197467 E041 17.1014055 0.002236249 0.59026735 0.76393087 10 69902748 69902855 108 + 1.255 1.210 -0.158
ENSG00000197467 E042 10.5948951 0.038284850 0.58564485 0.76069933 10 69904933 69904959 27 + 1.073 1.014 -0.215
ENSG00000197467 E043 12.1833042 0.033965951 0.55485057 0.73966604 10 69905787 69905822 36 + 1.136 1.072 -0.231
ENSG00000197467 E044 13.9215194 0.002656778 0.98722845 0.99545833 10 69917289 69917333 45 + 1.138 1.140 0.008
ENSG00000197467 E045 12.5688522 0.002992726 0.38912896 0.61982980 10 69918285 69918317 33 + 1.037 1.126 0.320
ENSG00000197467 E046 10.9731389 0.004971330 0.91538407 0.95983692 10 69919062 69919080 19 + 1.037 1.048 0.039
ENSG00000197467 E047 9.8946685 0.004752399 0.89500115 0.94920407 10 69919081 69919088 8 + 0.998 1.012 0.051
ENSG00000197467 E048 0.1723744 0.032480055 1.00000000   10 69919665 69919701 37 + 0.000 0.087 10.209
ENSG00000197467 E049 0.1723744 0.032480055 1.00000000   10 69919702 69919727 26 + 0.000 0.087 10.209
ENSG00000197467 E050 8.8484634 0.029195669 0.94297543 0.97377891 10 69921882 69921882 1 + 0.975 0.955 -0.072
ENSG00000197467 E051 9.4566661 0.057634914 0.83077683 0.91422489 10 69921883 69921884 2 + 0.973 0.991 0.068
ENSG00000197467 E052 14.3157156 0.056675832 0.70606453 0.83939885 10 69921885 69921935 51 + 1.178 1.132 -0.164
ENSG00000197467 E053 17.4632485 0.003980497 0.70801338 0.84053850 10 69922708 69922794 87 + 1.206 1.240 0.118
ENSG00000197467 E054 13.5160219 0.002559593 0.46210389 0.67459119 10 69923802 69923855 54 + 1.074 1.147 0.265
ENSG00000197467 E055 9.4037163 0.003154783 0.67268451 0.81800480 10 69924963 69924963 1 + 1.018 0.973 -0.169
ENSG00000197467 E056 12.5172578 0.002752041 0.84970045 0.92480183 10 69924964 69925007 44 + 1.091 1.111 0.074
ENSG00000197467 E057 6.2901696 0.005240895 0.91734489 0.96089622 10 69925804 69925804 1 + 0.853 0.842 -0.044
ENSG00000197467 E058 11.9432341 0.038311597 0.91325549 0.95873094 10 69925805 69925872 68 + 1.072 1.098 0.096
ENSG00000197467 E059 0.0000000       10 69927024 69927064 41 +      
ENSG00000197467 E060 0.2617363 0.238193749 0.58060946   10 69927065 69927086 22 + 0.000 0.155 11.166
ENSG00000197467 E061 6.6127407 0.049214707 0.76447570 0.87527174 10 69927087 69927087 1 + 0.822 0.879 0.219
ENSG00000197467 E062 8.4159402 0.012573817 0.43653843 0.65614688 10 69927088 69927110 23 + 0.880 0.982 0.382
ENSG00000197467 E063 10.0434550 0.027571831 0.44013127 0.65883145 10 69928937 69928999 63 + 0.952 1.053 0.371
ENSG00000197467 E064 9.5375957 0.004375608 0.57565179 0.75411226 10 69930043 69930078 36 + 0.955 1.020 0.242
ENSG00000197467 E065 8.3168034 0.004270508 0.87155131 0.93679837 10 69930079 69930087 9 + 0.932 0.951 0.074
ENSG00000197467 E066 11.2236014 0.002867742 0.92781263 0.96596833 10 69930400 69930452 53 + 1.056 1.048 -0.031
ENSG00000197467 E067 11.0905253 0.013629572 0.87644764 0.93943906 10 69930453 69930468 16 + 1.038 1.056 0.064
ENSG00000197467 E068 9.4833530 0.016471142 0.94095196 0.97273039 10 69930469 69930472 4 + 0.999 0.991 -0.031
ENSG00000197467 E069 16.0737154 0.013602645 0.28713824 0.52792785 10 69930473 69930552 80 + 1.123 1.237 0.405
ENSG00000197467 E070 0.0000000       10 69931160 69931256 97 +      
ENSG00000197467 E071 1.8517203 0.010968263 0.07561243 0.23603848 10 69932560 69932604 45 + 0.168 0.506 2.228
ENSG00000197467 E072 0.4644705 0.024632292 0.28289688   10 69932605 69932661 57 + 0.000 0.220 11.790
ENSG00000197467 E073 0.2922838 0.027730474 0.57401233   10 69933175 69934950 1776 + 0.168 0.086 -1.099
ENSG00000197467 E074 9.2025912 0.004009025 0.02505807 0.11241114 10 69935350 69935391 42 + 0.757 1.039 1.076
ENSG00000197467 E075 13.5043753 0.002417307 0.12778175 0.32832452 10 69936756 69936782 27 + 1.018 1.173 0.559
ENSG00000197467 E076 18.5228053 0.002424273 0.43523193 0.65514716 10 69937635 69937715 81 + 1.207 1.276 0.245
ENSG00000197467 E077 1.2570018 0.108501152 0.85605019   10 69940988 69941023 36 + 0.288 0.329 0.268
ENSG00000197467 E078 0.0000000       10 69941236 69941347 112 +      
ENSG00000197467 E079 0.3447487 0.375628364 0.61445434   10 69943866 69944124 259 + 0.000 0.161 11.231
ENSG00000197467 E080 14.0277225 0.083014504 0.83766257 0.91814924 10 69944125 69944178 54 + 1.120 1.155 0.126
ENSG00000197467 E081 14.1804786 0.028635061 0.67124260 0.81711490 10 69945671 69945724 54 + 1.179 1.136 -0.156
ENSG00000197467 E082 9.3100297 0.033939558 0.44064842 0.65918709 10 69947307 69947342 36 + 0.907 1.025 0.437
ENSG00000197467 E083 10.6857871 0.003711749 0.73839284 0.85950722 10 69952882 69952968 87 + 1.056 1.021 -0.127
ENSG00000197467 E084 0.7204775 0.056722271 0.76974217   10 69953948 69954025 78 + 0.168 0.222 0.506
ENSG00000197467 E085 11.8349534 0.011991497 0.99212770 0.99777313 10 69954091 69957003 2913 + 1.073 1.075 0.005
ENSG00000197467 E086 8.5839863 0.003914242 0.02300895 0.10598459 10 69957004 69957042 39 + 1.107 0.856 -0.933
ENSG00000197467 E087 0.8515333 0.019873278 0.70596260   10 69957867 69958698 832 + 0.288 0.221 -0.507
ENSG00000197467 E088 13.8135005 0.002577921 0.94274146 0.97366756 10 69958699 69959148 450 + 1.138 1.146 0.031
ENSG00000197467 E089 0.0000000       10 69964247 69964275 29 +