ENSG00000196700

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000369888 ENSG00000196700 HEK293_OSMI2_6hA HEK293_TMG_6hB ZNF512B protein_coding protein_coding 32.89757 48.96682 23.63002 2.598813 0.5433614 -1.050868 16.669912 27.3038125 5.054426 5.2122860 0.1803682 -2.43116012 0.47638333 0.554433333 0.21380000 -0.3406333 0.02568802 1.780698e-09 FALSE TRUE
MSTRG.21005.11 ENSG00000196700 HEK293_OSMI2_6hA HEK293_TMG_6hB ZNF512B protein_coding   32.89757 48.96682 23.63002 2.598813 0.5433614 -1.050868 4.275959 5.6546668 5.496156 0.9958138 0.1862466 -0.04094557 0.14240417 0.115266667 0.23246667 0.1172000 0.04332765 1.780698e-09 FALSE TRUE
MSTRG.21005.17 ENSG00000196700 HEK293_OSMI2_6hA HEK293_TMG_6hB ZNF512B protein_coding   32.89757 48.96682 23.63002 2.598813 0.5433614 -1.050868 1.284433 0.4706711 2.013114 0.2928058 0.3226961 2.07345594 0.04682083 0.009766667 0.08466667 0.0749000 0.10270096 1.780698e-09 FALSE TRUE
MSTRG.21005.18 ENSG00000196700 HEK293_OSMI2_6hA HEK293_TMG_6hB ZNF512B protein_coding   32.89757 48.96682 23.63002 2.598813 0.5433614 -1.050868 2.965868 4.4096021 3.389240 2.0826665 0.3039603 -0.37870447 0.09331250 0.092733333 0.14363333 0.0509000 0.65166112 1.780698e-09   FALSE
MSTRG.21005.7 ENSG00000196700 HEK293_OSMI2_6hA HEK293_TMG_6hB ZNF512B protein_coding   32.89757 48.96682 23.63002 2.598813 0.5433614 -1.050868 3.356976 4.4494242 4.253517 0.9795283 0.2236936 -0.06481346 0.10886667 0.091066667 0.17986667 0.0888000 0.17388757 1.780698e-09 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_6hB HEK293_OSMI2_6hA log2fold_HEK293_OSMI2_6hA_HEK293_TMG_6hB
ENSG00000196700 E001 0.0000000       20 63956472 63956580 109 -      
ENSG00000196700 E002 0.0000000       20 63956581 63956605 25 -      
ENSG00000196700 E003 0.6564337 1.139085e-01 3.397357e-01   20 63956606 63956703 98 - 0.319 0.141 -1.494
ENSG00000196700 E004 538.2111587 1.114988e-02 3.377004e-06 8.222121e-05 20 63956704 63957425 722 - 2.476 2.726 0.834
ENSG00000196700 E005 440.4709655 1.124776e-03 4.925424e-05 8.210958e-04 20 63957426 63957877 452 - 2.508 2.612 0.344
ENSG00000196700 E006 297.7173450 2.177909e-04 1.964187e-02 9.469530e-02 20 63957878 63958134 257 - 2.373 2.433 0.201
ENSG00000196700 E007 1578.3684509 9.801133e-05 1.815346e-07 6.327738e-06 20 63958135 63959705 1571 - 3.101 3.157 0.188
ENSG00000196700 E008 130.4622623 5.754156e-03 1.547142e-02 7.985297e-02 20 63959706 63959741 36 - 1.962 2.095 0.446
ENSG00000196700 E009 100.3111725 4.898527e-03 1.631123e-03 1.453941e-02 20 63959742 63959755 14 - 1.813 1.992 0.604
ENSG00000196700 E010 447.1902895 2.558083e-03 4.247387e-02 1.611709e-01 20 63959756 63960139 384 - 2.547 2.610 0.210
ENSG00000196700 E011 10.3866276 3.407576e-01 1.904808e-01 4.175762e-01 20 63960290 63960374 85 - 1.174 0.923 -0.917
ENSG00000196700 E012 45.2304411 1.126856e-01 3.168742e-02 1.322955e-01 20 63960798 63961308 511 - 1.814 1.505 -1.048
ENSG00000196700 E013 273.6655988 2.881227e-04 2.404611e-01 4.771042e-01 20 63961309 63961407 99 - 2.401 2.376 -0.085
ENSG00000196700 E014 212.0005124 5.814543e-04 1.974124e-01 4.263986e-01 20 63961942 63962004 63 - 2.298 2.264 -0.114
ENSG00000196700 E015 257.5179775 2.330353e-04 6.010704e-01 7.708735e-01 20 63962273 63962374 102 - 2.363 2.354 -0.031
ENSG00000196700 E016 291.0862107 2.102596e-03 9.218272e-01 9.631912e-01 20 63962587 63962781 195 - 2.405 2.411 0.019
ENSG00000196700 E017 217.6755296 6.139229e-03 4.299560e-01 6.510372e-01 20 63963095 63963242 148 - 2.255 2.293 0.127
ENSG00000196700 E018 98.7684022 1.868144e-02 3.887567e-01 6.194592e-01 20 63963243 63963265 23 - 1.890 1.959 0.231
ENSG00000196700 E019 138.5373950 9.541227e-03 5.971952e-01 7.684881e-01 20 63963342 63963380 39 - 2.066 2.095 0.096
ENSG00000196700 E020 178.5824994 6.381960e-03 8.404590e-01 9.196889e-01 20 63963381 63963440 60 - 2.206 2.193 -0.043
ENSG00000196700 E021 224.7251370 7.417093e-04 1.959826e-01 4.245361e-01 20 63963618 63963710 93 - 2.324 2.290 -0.113
ENSG00000196700 E022 279.1983920 2.839037e-04 4.455474e-01 6.624601e-01 20 63963789 63963913 125 - 2.403 2.388 -0.049
ENSG00000196700 E023 286.4443443 2.851630e-04 5.179071e-01 7.135356e-01 20 63964071 63964217 147 - 2.387 2.406 0.066
ENSG00000196700 E024 193.1758468 2.331587e-04 1.148017e-01 3.071053e-01 20 63964320 63964391 72 - 2.262 2.221 -0.137
ENSG00000196700 E025 8.8083364 4.555606e-02 4.554760e-02 1.689027e-01 20 63964392 63964395 4 - 1.130 0.844 -1.064
ENSG00000196700 E026 290.1189503 1.717325e-03 1.661050e-02 8.401555e-02 20 63964490 63964716 227 - 2.458 2.390 -0.230
ENSG00000196700 E027 259.6164801 3.748433e-03 3.374658e-02 1.381883e-01 20 63966141 63966281 141 - 2.416 2.340 -0.253
ENSG00000196700 E028 294.2510485 9.421551e-04 5.496619e-04 6.128232e-03 20 63966282 63966424 143 - 2.479 2.392 -0.292
ENSG00000196700 E029 151.7533957 5.165010e-03 3.965859e-02 1.538612e-01 20 63966425 63966443 19 - 2.195 2.103 -0.309
ENSG00000196700 E030 188.2956604 1.405670e-03 5.603217e-03 3.774814e-02 20 63966444 63966496 53 - 2.286 2.199 -0.293
ENSG00000196700 E031 410.5443699 1.712665e-04 1.191665e-03 1.136858e-02 20 63966497 63966781 285 - 2.603 2.543 -0.199
ENSG00000196700 E032 251.7612288 7.298685e-03 2.341994e-02 1.072930e-01 20 63966876 63967004 129 - 2.422 2.314 -0.359
ENSG00000196700 E033 232.2146390 3.657393e-03 8.535629e-04 8.719075e-03 20 63967381 63967523 143 - 2.400 2.274 -0.421
ENSG00000196700 E034 132.6355879 4.238129e-04 5.854527e-04 6.451741e-03 20 63967830 63967952 123 - 2.150 2.037 -0.380
ENSG00000196700 E035 40.6374721 6.175371e-02 1.497483e-04 2.094959e-03 20 63967953 63968145 193 - 1.861 1.378 -1.648
ENSG00000196700 E036 38.7016957 5.102525e-02 5.512173e-03 3.728417e-02 20 63968484 63968646 163 - 1.756 1.435 -1.093
ENSG00000196700 E037 55.3133557 2.998244e-02 7.006979e-04 7.448802e-03 20 63968647 63968878 232 - 1.905 1.587 -1.078
ENSG00000196700 E038 21.6195647 9.465015e-02 9.268286e-02 2.687558e-01 20 63969129 63969241 113 - 1.471 1.221 -0.870
ENSG00000196700 E039 8.5372554 3.786958e-03 2.055503e-01 4.365361e-01 20 63969518 63969813 296 - 0.807 0.975 0.642
ENSG00000196700 E040 19.8561386 2.939514e-03 8.008647e-02 2.450045e-01 20 63969814 63969936 123 - 1.129 1.298 0.597