ENSG00000196417

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000396408 ENSG00000196417 HEK293_OSMI2_6hA HEK293_TMG_6hB ZNF765 protein_coding protein_coding 2.257104 0.6417217 4.240889 0.05466858 0.1316679 2.705437 1.91250321 0.43580145 3.65152364 0.05640143 0.309072910 3.0379709 0.81002500 0.6779333 0.858633333 0.18070000 0.42508310 0.02428087 FALSE TRUE
ENST00000504235 ENSG00000196417 HEK293_OSMI2_6hA HEK293_TMG_6hB ZNF765 protein_coding nonsense_mediated_decay 2.257104 0.6417217 4.240889 0.05466858 0.1316679 2.705437 0.05046489 0.07636141 0.05008864 0.01361440 0.006105526 -0.5232945 0.03995833 0.1209000 0.011933333 -0.10896667 0.02428087 0.02428087 TRUE FALSE
ENST00000507045 ENSG00000196417 HEK293_OSMI2_6hA HEK293_TMG_6hB ZNF765 protein_coding nonsense_mediated_decay 2.257104 0.6417217 4.240889 0.05466858 0.1316679 2.705437 0.04887495 0.05504036 0.04157670 0.02752348 0.041576696 -0.3346158 0.03523750 0.0853000 0.009266667 -0.07603333 0.40430115 0.02428087 TRUE FALSE
ENST00000594030 ENSG00000196417 HEK293_OSMI2_6hA HEK293_TMG_6hB ZNF765 protein_coding protein_coding 2.257104 0.6417217 4.240889 0.05466858 0.1316679 2.705437 0.05835571 0.04830609 0.07270987 0.02755737 0.020716067 0.5044130 0.06313333 0.0809000 0.017433333 -0.06346667 0.32964161 0.02428087 FALSE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

No results under this category.

Splicing

All exons whithin this gene region are shown and numbering below.

No results under this category.

Transcripts

All isoforms whithin this gene region are shown below.

No results under this category.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_6hB HEK293_OSMI2_6hA log2fold_HEK293_OSMI2_6hA_HEK293_TMG_6hB
ENSG00000196417 E001 0.0000000       19 53389793 53390209 417 +      
ENSG00000196417 E002 0.0000000       19 53395144 53395148 5 +      
ENSG00000196417 E003 0.3040503 0.02444117 1.000000e+00   19 53395149 53395154 6 +      
ENSG00000196417 E004 2.5893721 0.15219473 7.648060e-01 0.875531834 19 53395155 53395160 6 +      
ENSG00000196417 E005 3.5722214 0.18015299 4.244453e-01 0.646879641 19 53395161 53395172 12 +      
ENSG00000196417 E006 3.8645053 0.18994940 5.801744e-01 0.757279321 19 53395173 53395193 21 +      
ENSG00000196417 E007 6.3529366 0.18915425 4.896460e-01 0.693746537 19 53397943 53398030 88 +      
ENSG00000196417 E008 4.5827151 0.49779731 4.832117e-01 0.689259325 19 53402065 53402191 127 +      
ENSG00000196417 E009 158.1926967 0.29193788 2.508373e-01 0.488895319 19 53407698 53412009 4312 +      
ENSG00000196417 E010 0.1614157 0.03123065 1.000000e+00   19 53423062 53423319 258 +      
ENSG00000196417 E011 0.1614157 0.03123065 1.000000e+00   19 53423320 53423374 55 +      
ENSG00000196417 E012 1.3160038 0.01327378 9.626351e-04   19 53423375 53423502 128 +      
ENSG00000196417 E013 2.0455028 0.35898498 8.776707e-01 0.940067645 19 53423503 53425070 1568 +      
ENSG00000196417 E014 1.9998623 0.01111628 3.852771e-02 0.150931759 19 53425071 53425147 77 +      
ENSG00000196417 E015 0.4842470 0.40317101 8.244968e-01   19 53425148 53425329 182 +      
ENSG00000196417 E016 2.8569373 0.01110866 7.415187e-05 0.001164911 19 53425330 53425451 122 +      
ENSG00000196417 E017 1.9704123 0.01081342 4.264794e-03 0.030629796 19 53425452 53426017 566 +      
ENSG00000196417 E018 1.5053967 0.57258216 2.717543e-01 0.511617016 19 53426018 53426042 25 +      
ENSG00000196417 E019 2.0421086 0.04814568 6.338788e-03 0.041399390 19 53426043 53426489 447 +      
ENSG00000196417 E020 0.6479912 0.17634418 2.633836e-03   19 53426490 53426584 95 +      
ENSG00000196417 E021 0.6479912 0.17634418 2.633836e-03   19 53426585 53426595 11 +      
ENSG00000196417 E022 2.2844413 0.27907907 1.804201e-01 0.404545637 19 53426596 53426864 269 +      
ENSG00000196417 E023 1.0103762 0.35412629 7.771348e-01   19 53426865 53426868 4 +      
ENSG00000196417 E024 1.1530109 0.25187094 6.480197e-01   19 53426869 53426936 68 +      
ENSG00000196417 E025 0.3150090 0.02749806 3.164179e-01   19 53426937 53427086 150 +      
ENSG00000196417 E026 5.4820591 0.32602254 5.462354e-02 0.190483045 19 53427087 53430413 3327 +