ENSG00000189079

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000334344 ENSG00000189079 HEK293_OSMI2_6hA HEK293_TMG_6hB ARID2 protein_coding protein_coding 4.948355 2.37549 9.140224 0.8061279 0.3121586 1.939521 2.3381405 1.04555032 4.7043424 0.27046675 0.15314285 2.159061 0.43867500 0.4914333 0.5160333 0.0246000 9.674700e-01 4.662829e-12 FALSE TRUE
ENST00000422737 ENSG00000189079 HEK293_OSMI2_6hA HEK293_TMG_6hB ARID2 protein_coding protein_coding 4.948355 2.37549 9.140224 0.8061279 0.3121586 1.939521 1.7319314 0.02055553 4.0409150 0.02055553 0.36735706 7.050670 0.22982917 0.0202000 0.4404667 0.4202667 1.459835e-08 4.662829e-12 FALSE TRUE
ENST00000444670 ENSG00000189079 HEK293_OSMI2_6hA HEK293_TMG_6hB ARID2 protein_coding protein_coding 4.948355 2.37549 9.140224 0.8061279 0.3121586 1.939521 0.1745378 0.62475434 0.0000000 0.14350423 0.00000000 -5.988126 0.07751667 0.2938333 0.0000000 -0.2938333 4.662829e-12 4.662829e-12 FALSE TRUE
ENST00000457135 ENSG00000189079 HEK293_OSMI2_6hA HEK293_TMG_6hB ARID2 protein_coding protein_coding 4.948355 2.37549 9.140224 0.8061279 0.3121586 1.939521 0.4352668 0.42493072 0.1549503 0.42493072 0.07783485 -1.398754 0.18197917 0.1116000 0.0174000 -0.0942000 1.000000e+00 4.662829e-12 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_6hB HEK293_OSMI2_6hA log2fold_HEK293_OSMI2_6hA_HEK293_TMG_6hB
ENSG00000189079 E001 1.5584793 0.131445854 0.6149170194 0.780249652 12 45729702 45729705 4 + 0.292 0.478 1.065
ENSG00000189079 E002 1.7612136 0.197826706 0.4236870105 0.646374279 12 45729706 45729712 7 + 0.292 0.571 1.506
ENSG00000189079 E003 12.5129314 0.123318358 0.7876230628 0.889147159 12 45729713 45729872 160 + 1.027 1.085 0.209
ENSG00000189079 E004 11.2638516 0.128944003 0.8484119251 0.924040067 12 45729873 45729885 13 + 0.985 1.057 0.264
ENSG00000189079 E005 12.9280573 0.063879216 0.7220878981 0.849347775 12 45729886 45729915 30 + 1.011 1.189 0.643
ENSG00000189079 E006 11.6405940 0.026568051 0.3725718375 0.606113618 12 45729916 45729928 13 + 0.952 1.189 0.860
ENSG00000189079 E007 23.1414538 0.052863838 0.5730807566 0.752377551 12 45730044 45730137 94 + 1.279 1.329 0.174
ENSG00000189079 E008 28.2158835 0.048816037 0.2086144482 0.440208395 12 45731217 45731314 98 + 1.377 1.343 -0.116
ENSG00000189079 E009 0.7982606 0.017285699 0.0097377018   12 45755931 45756005 75 + 0.064 0.558 4.040
ENSG00000189079 E010 0.1426347 0.031109886 1.0000000000   12 45776081 45776329 249 + 0.064 0.000 -8.816
ENSG00000189079 E011 36.5536172 0.046825923 0.0047733802 0.033389611 12 45811418 45811551 134 + 1.517 1.285 -0.802
ENSG00000189079 E012 50.6279486 0.082024016 0.0030439280 0.023677382 12 45817670 45817888 219 + 1.666 1.344 -1.107
ENSG00000189079 E013 31.2523888 0.092451017 0.0313994191 0.131487323 12 45821420 45821487 68 + 1.451 1.241 -0.728
ENSG00000189079 E014 31.9574179 0.042660566 0.0090451001 0.054022158 12 45836589 45836655 67 + 1.459 1.264 -0.677
ENSG00000189079 E015 23.2702212 0.028933028 0.0069369473 0.044340659 12 45836741 45836760 20 + 1.329 1.124 -0.724
ENSG00000189079 E016 43.8564459 0.020641516 0.0020235919 0.017215331 12 45836761 45836944 184 + 1.587 1.421 -0.567
ENSG00000189079 E017 21.6903052 0.018404642 0.0008551634 0.008733322 12 45836945 45836991 47 + 1.305 1.035 -0.962
ENSG00000189079 E018 31.0417032 0.043065230 0.0008131069 0.008388587 12 45837321 45837394 74 + 1.457 1.150 -1.076
ENSG00000189079 E019 21.0258776 0.059255989 0.0058499494 0.039006757 12 45837395 45837417 23 + 1.294 1.007 -1.029
ENSG00000189079 E020 47.2847781 0.042704319 0.0052154193 0.035756890 12 45837498 45837707 210 + 1.621 1.423 -0.679
ENSG00000189079 E021 18.5659091 0.038925811 0.1123763857 0.303102766 12 45839329 45839385 57 + 1.215 1.129 -0.308
ENSG00000189079 E022 24.4629586 0.054961778 0.0407148774 0.156582987 12 45839386 45839496 111 + 1.339 1.200 -0.489
ENSG00000189079 E023 0.1426347 0.031109886 1.0000000000   12 45839497 45842234 2738 + 0.064 0.000 -8.816
ENSG00000189079 E024 0.3206185 0.026002465 0.7907563901   12 45845990 45846072 83 + 0.120 0.000 -9.817
ENSG00000189079 E025 20.9594663 0.016363276 0.0010093867 0.009984220 12 45846856 45846937 82 + 1.292 1.033 -0.922
ENSG00000189079 E026 28.4576622 0.043868616 0.0226783601 0.104885949 12 45848836 45848970 135 + 1.404 1.251 -0.534
ENSG00000189079 E027 37.0354418 0.001088356 0.0046081419 0.032514894 12 45849580 45849776 197 + 1.509 1.424 -0.293
ENSG00000189079 E028 134.3936796 1.377757629 0.6360450123 0.794310239 12 45850036 45851286 1251 + 2.015 2.107 0.310
ENSG00000189079 E029 63.1135199 0.840882658 0.5142174333 0.711129139 12 45851287 45851838 552 + 1.682 1.812 0.437
ENSG00000189079 E030 71.1497774 0.868926395 0.4579175783 0.671703230 12 45851839 45852294 456 + 1.716 1.911 0.657
ENSG00000189079 E031 86.4473293 1.217542990 0.4961139569 0.698266576 12 45852295 45852896 602 + 1.771 2.059 0.968
ENSG00000189079 E032 42.1291575 0.010082492 0.0311118013 0.130689112 12 45860801 45860949 149 + 1.475 1.762 0.977
ENSG00000189079 E033 45.9759731 0.005898813 0.5165063712 0.712666276 12 45891780 45891918 139 + 1.541 1.710 0.577
ENSG00000189079 E034 33.1205443 0.012397327 0.9618258457 0.982911004 12 45892011 45892042 32 + 1.414 1.537 0.421
ENSG00000189079 E035 40.2393614 0.017836151 0.9739362912 0.988845030 12 45892043 45892096 54 + 1.497 1.612 0.394
ENSG00000189079 E036 45.3913028 0.001168886 0.9232009197 0.963879290 12 45893420 45893543 124 + 1.552 1.664 0.383
ENSG00000189079 E037 0.2922838 0.025647425 0.4043831226   12 45893544 45893629 86 + 0.064 0.218 2.039
ENSG00000189079 E038 28.9601386 0.001244990 0.2649032854 0.504220384 12 45893630 45893721 92 + 1.342 1.536 0.671
ENSG00000189079 E039 0.1723744 0.104115576 0.1506075496   12 45893722 45893918 197 + 0.000 0.219 12.870
ENSG00000189079 E040 1.0595171 0.378027692 0.7058943158   12 45904342 45904398 57 + 0.260 0.223 -0.285
ENSG00000189079 E041 200.3726854 1.390111837 0.2134144371 0.445718150 12 45904934 45908040 3107 + 2.026 2.581 1.854