ENSG00000185624

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000331483 ENSG00000185624 HEK293_OSMI2_6hA HEK293_TMG_6hB P4HB protein_coding protein_coding 493.1442 586.5243 322.2922 70.85311 7.190178 -0.8638015 430.2582 530.579 263.1257 69.42126 8.002553 -1.011788 0.8689458 0.9021 0.8162667 -0.08583333 0.01386573 6.267764e-07 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_6hB HEK293_OSMI2_6hA log2fold_HEK293_OSMI2_6hA_HEK293_TMG_6hB
ENSG00000185624 E001 6.189241 0.014475170 0.048054765 0.17512139 17 81843159 81843160 2 - 0.971 0.760 -0.813
ENSG00000185624 E002 15.989659 0.010825896 0.338148445 0.57638769 17 81843161 81843162 2 - 1.221 1.183 -0.136
ENSG00000185624 E003 70.929877 0.102724259 0.795548189 0.89376974 17 81843163 81843165 3 - 1.801 1.811 0.034
ENSG00000185624 E004 119.783843 0.162538250 0.194561588 0.42279824 17 81843166 81843167 2 - 1.875 2.078 0.683
ENSG00000185624 E005 119.956218 0.162050807 0.192650542 0.42032598 17 81843168 81843168 1 - 1.875 2.079 0.686
ENSG00000185624 E006 120.390328 0.162030644 0.189465963 0.41629808 17 81843169 81843169 1 - 1.875 2.081 0.692
ENSG00000185624 E007 125.015075 0.163838119 0.168279980 0.38827492 17 81843170 81843172 3 - 1.880 2.099 0.735
ENSG00000185624 E008 125.682280 0.164142555 0.164891465 0.38385693 17 81843173 81843173 1 - 1.880 2.102 0.745
ENSG00000185624 E009 128.099122 0.173542695 0.173490967 0.39520866 17 81843174 81843174 1 - 1.891 2.110 0.733
ENSG00000185624 E010 128.463272 0.175747969 0.177332791 0.40020713 17 81843175 81843175 1 - 1.894 2.111 0.726
ENSG00000185624 E011 128.463272 0.175747969 0.177332791 0.40020713 17 81843176 81843176 1 - 1.894 2.111 0.726
ENSG00000185624 E012 389.374762 0.783649612 0.330016253 0.56895995 17 81843177 81843189 13 - 2.377 2.588 0.704
ENSG00000185624 E013 394.055807 0.787413542 0.328875850 0.56783061 17 81843190 81843191 2 - 2.381 2.594 0.710
ENSG00000185624 E014 399.507167 0.792553786 0.328700555 0.56768325 17 81843192 81843193 2 - 2.386 2.600 0.712
ENSG00000185624 E015 475.353837 0.876259260 0.356915107 0.59322138 17 81843194 81843194 1 - 2.474 2.672 0.660
ENSG00000185624 E016 522.185488 0.896961733 0.338644780 0.57678671 17 81843195 81843198 4 - 2.496 2.717 0.738
ENSG00000185624 E017 541.601606 0.914128861 0.344762747 0.58229546 17 81843199 81843201 3 - 2.514 2.733 0.727
ENSG00000185624 E018 565.982929 0.937443390 0.355541510 0.59218787 17 81843202 81843203 2 - 2.539 2.750 0.703
ENSG00000185624 E019 573.166730 0.944497792 0.359199961 0.59520149 17 81843204 81843206 3 - 2.547 2.755 0.695
ENSG00000185624 E020 621.314132 0.981346288 0.371009281 0.60473288 17 81843207 81843208 2 - 2.586 2.789 0.675
ENSG00000185624 E021 643.977343 0.985735116 0.359303873 0.59527530 17 81843209 81843211 3 - 2.591 2.807 0.719
ENSG00000185624 E022 662.752296 0.989147466 0.349901000 0.58717218 17 81843212 81843216 5 - 2.595 2.822 0.754
ENSG00000185624 E023 927.324267 1.134521645 0.393214724 0.62293631 17 81843217 81843230 14 - 2.759 2.963 0.680
ENSG00000185624 E024 1021.952438 1.185085385 0.419710556 0.64345237 17 81843231 81843237 7 - 2.817 3.001 0.612
ENSG00000185624 E025 1607.971317 1.333982353 0.421569118 0.64483474 17 81843238 81843266 29 - 2.997 3.202 0.682
ENSG00000185624 E026 2339.113600 1.467759925 0.445470819 0.66241575 17 81843267 81843330 64 - 3.166 3.363 0.657
ENSG00000185624 E027 1562.418325 1.339275686 0.441126614 0.65956008 17 81843331 81843333 3 - 3.003 3.185 0.605
ENSG00000185624 E028 2183.952885 1.450344745 0.451399213 0.66664923 17 81843334 81843363 30 - 3.144 3.332 0.625
ENSG00000185624 E029 2684.756028 1.512168200 0.449352327 0.66528074 17 81843364 81843421 58 - 3.224 3.424 0.664
ENSG00000185624 E030 1788.633104 1.385545551 0.447704877 0.66404061 17 81843422 81843430 9 - 3.062 3.244 0.605
ENSG00000185624 E031 2961.244029 1.538784807 0.445882429 0.66268546 17 81843431 81843513 83 - 3.258 3.468 0.698
ENSG00000185624 E032 1665.437615 1.335319429 0.408245650 0.63466469 17 81843514 81843521 8 - 2.997 3.221 0.745
ENSG00000185624 E033 5861.482776 1.764950062 0.481264516 0.68790976 17 81843522 81843878 357 - 3.564 3.763 0.664
ENSG00000185624 E034 3313.345693 1.603066426 0.494067165 0.69673168 17 81843879 81844040 162 - 3.346 3.507 0.535
ENSG00000185624 E035 2342.789980 1.519551999 0.527626035 0.72034852 17 81844041 81844092 52 - 3.233 3.347 0.377
ENSG00000185624 E036 95.615057 0.326153248 0.811587304 0.90322156 17 81844093 81845143 1051 - 1.982 1.916 -0.222
ENSG00000185624 E037 3264.761137 1.641692372 0.562899446 0.74536084 17 81845144 81845230 87 - 3.395 3.486 0.301
ENSG00000185624 E038 282.755600 0.754395825 0.474074360 0.68288736 17 81845231 81845303 73 - 2.343 2.422 0.262
ENSG00000185624 E039 77.482450 0.285763997 0.875440366 0.93898346 17 81845304 81845459 156 - 1.887 1.828 -0.197
ENSG00000185624 E040 87.996523 0.268595278 0.759814990 0.87246145 17 81845460 81845560 101 - 1.922 1.891 -0.105
ENSG00000185624 E041 2684.511980 1.589495765 0.576558507 0.75480766 17 81845561 81845626 66 - 3.325 3.396 0.235
ENSG00000185624 E042 3463.553771 1.660501386 0.566827163 0.74788613 17 81845627 81845742 116 - 3.420 3.511 0.302
ENSG00000185624 E043 23.637527 0.148191618 0.866908171 0.93430984 17 81845743 81845817 75 - 1.283 1.365 0.288
ENSG00000185624 E044 20.355490 0.146776867 0.965491767 0.98466047 17 81845818 81845870 53 - 1.250 1.294 0.155
ENSG00000185624 E045 2566.171366 1.538585888 0.514663035 0.71145815 17 81845871 81845946 76 - 3.258 3.390 0.441
ENSG00000185624 E046 2692.134450 1.559134439 0.524524746 0.71814929 17 81845947 81845991 45 - 3.285 3.409 0.414
ENSG00000185624 E047 10.552745 0.004523443 0.008717404 0.05256038 17 81845992 81846010 19 - 0.668 1.085 1.610
ENSG00000185624 E048 12.080481 0.096486792 0.491569222 0.69504116 17 81846011 81846359 349 - 1.125 1.048 -0.280
ENSG00000185624 E049 5.423281 0.119109340 0.882891778 0.94278849 17 81846360 81846428 69 - 0.754 0.775 0.082
ENSG00000185624 E050 2044.489896 1.471920836 0.519608053 0.71478386 17 81846429 81846430 2 - 3.171 3.288 0.389
ENSG00000185624 E051 2176.786900 1.494943420 0.525695606 0.71899301 17 81846431 81846442 12 - 3.201 3.315 0.378
ENSG00000185624 E052 2332.425604 1.529304952 0.547953356 0.73485029 17 81846443 81846469 27 - 3.246 3.340 0.313
ENSG00000185624 E053 2829.737568 1.604076737 0.574902931 0.75360208 17 81846470 81846509 40 - 3.345 3.420 0.248
ENSG00000185624 E054 4271.673103 1.737392406 0.591928060 0.76502982 17 81846510 81846629 120 - 3.526 3.598 0.241
ENSG00000185624 E055 18.804512 0.088210344 0.696947152 0.83358093 17 81846630 81846946 317 - 1.156 1.278 0.430
ENSG00000185624 E056 3138.263843 1.648044610 0.598210447 0.76903780 17 81846947 81847012 66 - 3.404 3.460 0.188
ENSG00000185624 E057 2825.351532 1.617509985 0.600583861 0.77059561 17 81847013 81847068 56 - 3.363 3.413 0.166
ENSG00000185624 E058 1783.369687 1.472130114 0.595755743 0.76758334 17 81847069 81847072 4 - 3.172 3.210 0.129
ENSG00000185624 E059 3416.085209 1.686028995 0.620278533 0.78401245 17 81847243 81847347 105 - 3.455 3.492 0.122
ENSG00000185624 E060 7.897152 0.028470975 0.903504707 0.95364575 17 81847348 81847371 24 - 0.889 0.921 0.122
ENSG00000185624 E061 9.440678 0.179051608 0.474574816 0.68325239 17 81847372 81848528 1157 - 0.715 1.040 1.248
ENSG00000185624 E062 2.141359 0.226248522 0.694941821 0.83226686 17 81853247 81853280 34 - 0.313 0.505 1.060
ENSG00000185624 E063 1.844533 0.247412492 0.174519996 0.39653616 17 81853281 81853403 123 - 0.561 0.346 -1.118
ENSG00000185624 E064 1.885232 0.610622148 0.626294522 0.78812042 17 81854894 81855027 134 - 0.418 0.423 0.024
ENSG00000185624 E065 3302.072887 0.034752683 0.037587027 0.14854880 17 81855142 81855279 138 - 3.496 3.457 -0.129
ENSG00000185624 E066 12.549330 0.021895568 0.164639125 0.38355818 17 81855280 81855452 173 - 1.147 1.052 -0.344
ENSG00000185624 E067 1901.095323 0.136872752 0.159122407 0.37546924 17 81855453 81855505 53 - 3.281 3.207 -0.246
ENSG00000185624 E068 2226.271571 0.178345953 0.210074095 0.44193760 17 81855506 81855579 74 - 3.352 3.274 -0.260
ENSG00000185624 E069 1364.385439 0.173113031 0.186230142 0.41208336 17 81855580 81855586 7 - 3.151 3.056 -0.314
ENSG00000185624 E070 18.125915 0.173377881 0.125328580 0.32433750 17 81855587 81855688 102 - 1.343 1.181 -0.568
ENSG00000185624 E071 152.764269 0.243788289 0.027779944 0.12065044 17 81855689 81858494 2806 - 2.371 2.002 -1.233
ENSG00000185624 E072 35.636381 0.265529457 0.024281842 0.10996298 17 81858495 81858934 440 - 1.767 1.365 -1.375
ENSG00000185624 E073 31.163782 0.263809720 0.044578355 0.16655840 17 81858935 81859178 244 - 1.679 1.336 -1.175
ENSG00000185624 E074 21.716031 0.198133706 0.135851208 0.34111543 17 81859179 81859180 2 - 1.430 1.250 -0.628
ENSG00000185624 E075 2565.478538 0.190655718 0.213754244 0.44607229 17 81859181 81859289 109 - 3.418 3.334 -0.281
ENSG00000185624 E076 2017.908191 0.201574001 0.249846644 0.48771460 17 81859290 81859346 57 - 3.308 3.232 -0.255
ENSG00000185624 E077 1592.673580 0.196619151 0.318444597 0.55832353 17 81859347 81859387 41 - 3.181 3.140 -0.139
ENSG00000185624 E078 130.293601 0.250472629 0.025741826 0.11451229 17 81859388 81859766 379 - 2.304 1.932 -1.244
ENSG00000185624 E079 48.211142 0.278424742 0.024908622 0.11195069 17 81859767 81859810 44 - 1.904 1.483 -1.429
ENSG00000185624 E080 44.553101 0.288142544 0.036129422 0.14456451 17 81859811 81859841 31 - 1.862 1.457 -1.378
ENSG00000185624 E081 43.671010 0.321751189 0.043809354 0.16462363 17 81859842 81859884 43 - 1.846 1.456 -1.328
ENSG00000185624 E082 64.313901 0.281308284 0.080678754 0.24618196 17 81859885 81860326 442 - 1.947 1.671 -0.930
ENSG00000185624 E083 1057.919718 0.191684622 0.285181021 0.52576610 17 81860327 81860331 5 - 3.015 2.957 -0.191
ENSG00000185624 E084 988.496731 0.193114050 0.308271026 0.54890181 17 81860332 81860336 5 - 2.979 2.931 -0.159
ENSG00000185624 E085 1086.075106 0.195275739 0.327364035 0.56646707 17 81860337 81860346 10 - 3.014 2.974 -0.133
ENSG00000185624 E086 1728.026881 0.214397338 0.497345161 0.69912626 17 81860347 81860624 278 - 3.171 3.192 0.071
ENSG00000185624 E087 22.260720 0.183586206 0.122799831 0.32015960 17 81860699 81860856 158 - 1.440 1.263 -0.617