ENSG00000184867

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000328766 ENSG00000184867 HEK293_OSMI2_6hA HEK293_TMG_6hB ARMCX2 protein_coding protein_coding 0.2779464 0.1856278 0.4090436 0.03169521 0.1911699 1.098989 0.02343569 0.0000000 0.00000000 0.00000000 0.00000000 0.000000 0.05503333 0 0.00000000 0.0000000   3.668607e-05 FALSE TRUE
ENST00000330154 ENSG00000184867 HEK293_OSMI2_6hA HEK293_TMG_6hB ARMCX2 protein_coding protein_coding 0.2779464 0.1856278 0.4090436 0.03169521 0.1911699 1.098989 0.12172013 0.1856278 0.01911522 0.03169521 0.01911522 -2.748266 0.62295000 1 0.02466667 -0.9753333 3.668607e-05 3.668607e-05 FALSE TRUE
ENST00000356824 ENSG00000184867 HEK293_OSMI2_6hA HEK293_TMG_6hB ARMCX2 protein_coding protein_coding 0.2779464 0.1856278 0.4090436 0.03169521 0.1911699 1.098989 0.02426716 0.0000000 0.08723836 0.00000000 0.04361925 3.281526 0.10032500 0 0.46926667 0.4692667 7.346121e-01 3.668607e-05 FALSE TRUE
ENST00000431597 ENSG00000184867 HEK293_OSMI2_6hA HEK293_TMG_6hB ARMCX2 protein_coding protein_coding 0.2779464 0.1856278 0.4090436 0.03169521 0.1911699 1.098989 0.06204168 0.0000000 0.11719269 0.00000000 0.05918277 3.668944 0.15955833 0 0.26680000 0.2668000 4.096763e-01 3.668607e-05   FALSE
ENST00000488982 ENSG00000184867 HEK293_OSMI2_6hA HEK293_TMG_6hB ARMCX2 protein_coding processed_transcript 0.2779464 0.1856278 0.4090436 0.03169521 0.1911699 1.098989 0.04648175 0.0000000 0.18549734 0.00000000 0.18549734 4.289077 0.06213333 0 0.23926667 0.2392667 8.778287e-01 3.668607e-05   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_6hB HEK293_OSMI2_6hA log2fold_HEK293_OSMI2_6hA_HEK293_TMG_6hB
ENSG00000184867 E001 8.0452108 0.009055646 0.000628445 0.00682643 X 101655281 101657086 1806 - 0.854 0.995 0.534
ENSG00000184867 E002 0.3150090 0.032852783 0.969847888   X 101657087 101657092 6 - 0.149 0.098 -0.684
ENSG00000184867 E003 1.1188791 0.014650017 0.775812800   X 101657093 101657274 182 - 0.348 0.305 -0.273
ENSG00000184867 E004 0.5421338 0.025799639 0.530244445   X 101657275 101657310 36 - 0.260 0.099 -1.686
ENSG00000184867 E005 0.8038701 0.019694658 0.716358492   X 101657311 101657356 46 - 0.260 0.246 -0.106
ENSG00000184867 E006 0.6424544 0.022166724 0.343726269   X 101657357 101657400 44 - 0.149 0.246 0.894
ENSG00000184867 E007 1.0470130 0.017116786 0.785206633   X 101657401 101657517 117 - 0.348 0.304 -0.277
ENSG00000184867 E008 1.2084287 0.017542148 0.902360374   X 101657518 101657666 149 - 0.421 0.304 -0.692
ENSG00000184867 E009 0.4514866 0.024355304 0.525078363   X 101657667 101657715 49 - 0.260 0.098 -1.690
ENSG00000184867 E010 0.0000000       X 101657716 101658072 357 -      
ENSG00000184867 E011 0.1779838 0.034829292 0.465570660   X 101658073 101658080 8 - 0.149 0.000 -12.582
ENSG00000184867 E012 0.8380019 0.019937219 0.012942732   X 101658081 101658142 62 - 0.484 0.000 -14.477
ENSG00000184867 E013 0.3206185 0.028776445 0.184355984   X 101658461 101658491 31 - 0.260 0.000 -13.409
ENSG00000184867 E014 0.3206185 0.028776445 0.184355984   X 101658492 101658525 34 - 0.260 0.000 -13.409
ENSG00000184867 E015 0.0000000       X 101658526 101658569 44 -      
ENSG00000184867 E016 0.0000000       X 101658570 101658649 80 -      
ENSG00000184867 E017 0.9994175 0.017961960 0.005471192   X 101659076 101659136 61 - 0.539 0.000 -14.693
ENSG00000184867 E018 0.1614157 0.036415771 0.463117876   X 101659137 101659148 12 - 0.149 0.000 -12.580
ENSG00000184867 E019 0.1614157 0.036415771 0.463117876   X 101659149 101659177 29 - 0.149 0.000 -12.580
ENSG00000184867 E020 0.0000000       X 101659200 101659407 208 -      
ENSG00000184867 E021 0.0000000       X 101659408 101659418 11 -      
ENSG00000184867 E022 0.0000000       X 101659419 101659501 83 -      
ENSG00000184867 E023 0.1779838 0.034829292 0.465570660   X 101659758 101659850 93 - 0.149 0.000 -12.582