ENSG00000184319

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000427528 ENSG00000184319 HEK293_OSMI2_6hA HEK293_TMG_6hB RPL23AP82 transcribed_unprocessed_pseudogene transcribed_unprocessed_pseudogene 30.81904 20.37593 27.29042 1.312899 3.322846 0.4213494 4.3202715 0.0000000 6.1253373 0.00000000 3.9992061 9.26099884 0.13015000 0.00000000 0.20306667 0.2030667 3.232856e-01 7.927014e-05 FALSE TRUE
ENST00000463325 ENSG00000184319 HEK293_OSMI2_6hA HEK293_TMG_6hB RPL23AP82 transcribed_unprocessed_pseudogene processed_transcript 30.81904 20.37593 27.29042 1.312899 3.322846 0.4213494 0.8210077 1.4513935 0.2839069 0.59974313 0.2839069 -2.31391357 0.02919167 0.07073333 0.01133333 -0.0594000 2.582761e-01 7.927014e-05   FALSE
ENST00000651346 ENSG00000184319 HEK293_OSMI2_6hA HEK293_TMG_6hB RPL23AP82 transcribed_unprocessed_pseudogene processed_transcript 30.81904 20.37593 27.29042 1.312899 3.322846 0.4213494 2.0096378 0.7811725 2.6799053 0.08836721 0.2795807 1.76549125 0.06507917 0.03813333 0.09863333 0.0605000 7.927014e-05 7.927014e-05 FALSE FALSE
MSTRG.22394.3 ENSG00000184319 HEK293_OSMI2_6hA HEK293_TMG_6hB RPL23AP82 transcribed_unprocessed_pseudogene   30.81904 20.37593 27.29042 1.312899 3.322846 0.4213494 15.0728662 11.9206069 12.2567906 1.14941571 1.6293510 0.04009041 0.49430417 0.58286667 0.46840000 -0.1144667 7.448770e-01 7.927014e-05 TRUE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_6hB HEK293_OSMI2_6hA log2fold_HEK293_OSMI2_6hA_HEK293_TMG_6hB
ENSG00000184319 E001 13.9764096 0.0417498694 8.307204e-02 2.508989e-01 22 50756948 50757326 379 + 1.285 1.054 -0.824
ENSG00000184319 E002 5.9457853 0.1236079437 6.610090e-01 8.105482e-01 22 50783120 50783253 134 + 0.802 0.870 0.264
ENSG00000184319 E003 4.7595343 0.1434517367 9.525438e-01 9.782932e-01 22 50783254 50783294 41 + 0.733 0.766 0.133
ENSG00000184319 E004 0.0000000       22 50783740 50783744 5 +      
ENSG00000184319 E005 0.0000000       22 50783745 50783754 10 +      
ENSG00000184319 E006 0.1308682 0.0317764246 4.855654e-01   22 50783755 50783763 9 + 0.000 0.122 10.125
ENSG00000184319 E007 1.0666018 0.0322297302 2.681661e-01   22 50783764 50783765 2 + 0.415 0.217 -1.302
ENSG00000184319 E008 1.4709728 0.1893631146 5.296177e-01 7.217879e-01 22 50783766 50783768 3 + 0.464 0.352 -0.615
ENSG00000184319 E009 2.3517684 0.1732926816 6.204373e-01 7.841041e-01 22 50783769 50783774 6 + 0.585 0.501 -0.391
ENSG00000184319 E010 4.1993226 0.0541641749 4.491892e-01 6.651434e-01 22 50783775 50783780 6 + 0.786 0.657 -0.526
ENSG00000184319 E011 6.1633406 0.0051238756 2.928185e-01 5.335262e-01 22 50783781 50783784 4 + 0.921 0.793 -0.496
ENSG00000184319 E012 7.8934567 0.0044627974 4.386613e-01 6.577582e-01 22 50783785 50783788 4 + 0.997 0.912 -0.319
ENSG00000184319 E013 18.2559599 0.0018852562 6.926779e-01 8.308166e-01 22 50783789 50783796 8 + 1.298 1.269 -0.099
ENSG00000184319 E014 29.5656109 0.0014012920 2.784859e-01 5.185727e-01 22 50783797 50783809 13 + 1.513 1.448 -0.225
ENSG00000184319 E015 62.7646588 0.0009336625 6.779971e-01 8.214334e-01 22 50783810 50783864 55 + 1.788 1.810 0.075
ENSG00000184319 E016 13.3975331 0.0340443408 2.504745e-01 4.885150e-01 22 50783865 50783874 10 + 1.085 1.232 0.528
ENSG00000184319 E017 32.5194541 0.0015242393 5.790199e-01 7.565301e-01 22 50783875 50783979 105 + 1.509 1.546 0.127
ENSG00000184319 E018 31.9928067 0.0010987022 4.451762e-01 6.621980e-01 22 50783980 50784021 42 + 1.538 1.496 -0.147
ENSG00000184319 E019 9.6276416 0.0802319253 8.112651e-01 9.030069e-01 22 50784022 50784072 51 + 1.018 1.057 0.146
ENSG00000184319 E020 6.6365888 0.0045286455 3.379746e-01 5.762604e-01 22 50784073 50784330 258 + 0.808 0.929 0.465
ENSG00000184319 E021 7.3468323 0.0888534764 9.826217e-02 2.787289e-01 22 50784331 50784424 94 + 0.735 1.049 1.202
ENSG00000184319 E022 3.7599942 0.0924494686 2.772895e-01 5.173091e-01 22 50784625 50784686 62 + 0.552 0.754 0.866
ENSG00000184319 E023 149.4896324 0.0005841356 2.164021e-02 1.014189e-01 22 50785173 50785293 121 + 2.140 2.206 0.220
ENSG00000184319 E024 9.6918707 0.0375104637 1.100987e-02 6.241376e-02 22 50788750 50788798 49 + 0.827 1.180 1.305
ENSG00000184319 E025 2.1230822 0.1823115630 9.889333e-01 9.962839e-01 22 50788799 50788802 4 + 0.510 0.473 -0.183
ENSG00000184319 E026 2.0737537 0.0114586546 7.677983e-01 8.772956e-01 22 50788803 50788891 89 + 0.465 0.516 0.250
ENSG00000184319 E027 4.8234579 0.0056357055 1.418014e-01 3.501694e-01 22 50788892 50788894 3 + 0.655 0.857 0.817
ENSG00000184319 E028 12.7886676 0.0111073578 4.022352e-04 4.753140e-03 22 50788895 50789354 460 + 0.921 1.296 1.357
ENSG00000184319 E029 0.2027342 0.0335327405 4.847072e-01   22 50791177 50791303 127 + 0.000 0.123 10.118
ENSG00000184319 E030 176.0992950 0.0176463952 9.983004e-01 1.000000e+00 22 50798655 50799247 593 + 2.238 2.255 0.057
ENSG00000184319 E031 39.4536808 0.0011639381 1.200630e-17 2.590783e-15 22 50799248 50801309 2062 + 1.788 1.284 -1.727
ENSG00000184319 E032 0.0000000       22 50801953 50801995 43 +