ENSG00000184208

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000472110 ENSG00000184208 HEK293_OSMI2_6hA HEK293_TMG_6hB C22orf46 transcribed_unitary_pseudogene processed_transcript 9.019679 11.93427 4.551829 0.5934168 0.09697001 -1.388635 0.6320123 0.0000000 1.6349392 0.0000000 0.3639239 7.361890 0.09107917 0.00000000 0.36283333 0.362833333 3.235831e-11 3.235831e-11 FALSE TRUE
ENST00000656592 ENSG00000184208 HEK293_OSMI2_6hA HEK293_TMG_6hB C22orf46 transcribed_unitary_pseudogene processed_transcript 9.019679 11.93427 4.551829 0.5934168 0.09697001 -1.388635 3.7832453 4.9247894 1.7661794 0.3604878 0.5208016 -1.474211 0.41602917 0.41506667 0.38543333 -0.029633333 9.622523e-01 3.235831e-11 FALSE TRUE
ENST00000664954 ENSG00000184208 HEK293_OSMI2_6hA HEK293_TMG_6hB C22orf46 transcribed_unitary_pseudogene processed_transcript 9.019679 11.93427 4.551829 0.5934168 0.09697001 -1.388635 2.3665916 3.9698491 0.2110989 0.7969234 0.2110989 -4.169950 0.24622917 0.32903333 0.04746667 -0.281566667 1.424614e-01 3.235831e-11 FALSE TRUE
ENST00000668666 ENSG00000184208 HEK293_OSMI2_6hA HEK293_TMG_6hB C22orf46 transcribed_unitary_pseudogene processed_transcript 9.019679 11.93427 4.551829 0.5934168 0.09697001 -1.388635 1.7942000 2.1266560 0.8164884 0.3175298 0.4307423 -1.370288 0.20004583 0.18183333 0.17670000 -0.005133333 9.466394e-01 3.235831e-11 FALSE TRUE
MSTRG.22213.5 ENSG00000184208 HEK293_OSMI2_6hA HEK293_TMG_6hB C22orf46 transcribed_unitary_pseudogene   9.019679 11.93427 4.551829 0.5934168 0.09697001 -1.388635 0.3161376 0.7919122 0.0000000 0.3131308 0.0000000 -6.325372 0.03102500 0.06453333 0.00000000 -0.064533333 1.786147e-03 3.235831e-11 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_6hB HEK293_OSMI2_6hA log2fold_HEK293_OSMI2_6hA_HEK293_TMG_6hB
ENSG00000184208 E001 0.000000       22 41688877 41688920 44 +      
ENSG00000184208 E002 0.000000       22 41688937 41688938 2 +      
ENSG00000184208 E003 5.444778 0.0079607038 9.270826e-01 0.9655908756 22 41688939 41688983 45 + 0.697 0.786 0.364
ENSG00000184208 E004 26.214442 0.0018121452 3.198703e-01 0.5595695731 22 41688984 41689237 254 + 1.365 1.378 0.044
ENSG00000184208 E005 20.624360 0.0417129435 3.048044e-02 0.1287824038 22 41689238 41689304 67 + 1.376 1.229 -0.513
ENSG00000184208 E006 6.184701 0.0047581332 7.352127e-01 0.8573863039 22 41690543 41690627 85 + 0.697 0.825 0.513
ENSG00000184208 E007 9.704861 0.0054370140 5.220326e-02 0.1848538154 22 41690628 41690783 156 + 1.072 0.930 -0.523
ENSG00000184208 E008 26.980496 0.0211458104 3.305564e-03 0.0252319658 22 41690784 41690843 60 + 1.508 1.335 -0.599
ENSG00000184208 E009 78.796558 0.0891573374 3.916649e-02 0.1525998791 22 41693463 41693851 389 + 1.947 1.791 -0.525
ENSG00000184208 E010 25.479449 0.0241945259 6.532231e-03 0.0423806309 22 41693852 41693937 86 + 1.478 1.306 -0.595
ENSG00000184208 E011 66.703976 0.0533253093 3.076920e-02 0.1296636937 22 41693938 41694104 167 + 1.849 1.732 -0.395
ENSG00000184208 E012 375.993274 0.0003368508 5.878452e-05 0.0009572312 22 41694105 41695628 1524 + 2.496 2.514 0.061
ENSG00000184208 E013 81.782644 0.0358120803 8.008847e-02 0.2450044649 22 41695629 41695799 171 + 1.662 1.898 0.795
ENSG00000184208 E014 268.372330 0.9499104229 3.617225e-01 0.5970711332 22 41695800 41696778 979 + 2.165 2.409 0.815
ENSG00000184208 E015 289.167487 0.9026003858 2.552060e-01 0.4938057000 22 41696779 41698136 1358 + 2.120 2.453 1.114