ENSG00000183474

1 Isoform Switch

Summary Plot
Results

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Rows: 1-7 / 7
Columns:
Select all:
isoform_id
gene_id
condition_1
condition_2
gene_name
gene_biotype
iso_biotype
gene_overall_mean
gene_value_1
gene_value_2
gene_stderr_1
gene_stderr_2
gene_log2_fold_change
iso_overall_mean
iso_value_1
iso_value_2
iso_stderr_1
iso_stderr_2
iso_log2_fold_change
IF_overall
IF1
IF2
dIF
isoform_switch_q_value
gene_switch_q_value
PTC
codingPotential
Close
Columns▼Records:
Use the filters above each column to filter and limit table data. Advanced searches can be performed by using the following operators:
<, <=, >, >=, =, *, !, {, }, ||,&&, **[empty]**, **[nonempty]**, **rgx:**
Learn more
TableFilter v0.7.3
https://www.tablefilter.com/
©2015-2025 Max Guglielmi
Close
?
Page of 1
isoform_id	gene_id	condition_1	condition_2	gene_name	gene_biotype	iso_biotype	gene_overall_mean	gene_value_1	gene_value_2	gene_stderr_1	gene_stderr_2	gene_log2_fold_change	iso_overall_mean	iso_value_1	iso_value_2	iso_stderr_1	iso_stderr_2	iso_log2_fold_change	IF_overall	IF1	IF2	dIF	isoform_switch_q_value	gene_switch_q_value	PTC	codingPotential

ENST00000380729	ENSG00000183474	HEK293_OSMI2_6hA	HEK293_TMG_6hB	GTF2H2C	protein_coding	protein_coding	27.69423	7.569268	52.49098	0.6310242	0.8560988	2.792214	2.4334623	0.6217665	1.757909	0.07917297	0.4748449	1.484581	0.09763333	0.08186667	0.03343333	-0.04843333	1.196685e-01	4.617992e-05	FALSE	TRUE
ENST00000510979	ENSG00000183474	HEK293_OSMI2_6hA	HEK293_TMG_6hB	GTF2H2C	protein_coding	protein_coding	27.69423	7.569268	52.49098	0.6310242	0.8560988	2.792214	1.3053486	0.0000000	3.408333	0.00000000	0.9492656	8.417149	0.03637083	0.00000000	0.06536667	0.06536667	4.617992e-05	4.617992e-05	FALSE	TRUE
MSTRG.26326.12	ENSG00000183474	HEK293_OSMI2_6hA	HEK293_TMG_6hB	GTF2H2C	protein_coding		27.69423	7.569268	52.49098	0.6310242	0.8560988	2.792214	8.9277595	2.2010509	17.656943	1.10769370	1.8592403	2.998248	0.31713333	0.27750000	0.33556667	0.05806667	9.189803e-01	4.617992e-05	TRUE	TRUE
MSTRG.26326.14	ENSG00000183474	HEK293_OSMI2_6hA	HEK293_TMG_6hB	GTF2H2C	protein_coding		27.69423	7.569268	52.49098	0.6310242	0.8560988	2.792214	0.6934966	0.0000000	0.000000	0.00000000	0.0000000	0.000000	0.05002083	0.00000000	0.00000000	0.00000000		4.617992e-05	TRUE	TRUE
MSTRG.26326.3	ENSG00000183474	HEK293_OSMI2_6hA	HEK293_TMG_6hB	GTF2H2C	protein_coding		27.69423	7.569268	52.49098	0.6310242	0.8560988	2.792214	4.3927994	0.6727125	10.331208	0.40467520	0.9668209	3.920983	0.11740417	0.09400000	0.19716667	0.10316667	6.746151e-01	4.617992e-05	TRUE	TRUE
MSTRG.26326.4	ENSG00000183474	HEK293_OSMI2_6hA	HEK293_TMG_6hB	GTF2H2C	protein_coding		27.69423	7.569268	52.49098	0.6310242	0.8560988	2.792214	0.6580874	0.9756874	2.624932	0.26903657	1.3339015	1.418563	0.03675000	0.13576667	0.05016667	-0.08560000	7.485227e-01	4.617992e-05	TRUE	TRUE
MSTRG.26326.8	ENSG00000183474	HEK293_OSMI2_6hA	HEK293_TMG_6hB	GTF2H2C	protein_coding		27.69423	7.569268	52.49098	0.6310242	0.8560988	2.792214	5.0283411	2.0282888	8.944172	0.40089124	1.2457161	2.135202	0.18521250	0.26450000	0.16980000	-0.09470000	4.223146e-01	4.617992e-05	TRUE	TRUE

Note:
- The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

All exons whithin this gene region are shown and numbering below.

All isoforms whithin this gene region are shown below.

Rows: 1-10 / 45
Columns:
Select all:
groupID
featureID
exonBaseMean
dispersion
pvalue
padj
seqnames
start
end
width
strand
HEK293_TMG_6hB
HEK293_OSMI2_6hA
log2fold_HEK293_OSMI2_6hA_HEK293_TMG_6hB
Close
Columns▼Records:
Use the filters above each column to filter and limit table data. Advanced searches can be performed by using the following operators:
<, <=, >, >=, =, *, !, {, }, ||,&&, **[empty]**, **[nonempty]**, **rgx:**
Learn more
TableFilter v0.7.3
https://www.tablefilter.com/
©2015-2025 Max Guglielmi
Close
?
Page of 5
groupID	featureID	exonBaseMean	dispersion	pvalue	padj	seqnames	start	end	width	strand	HEK293_TMG_6hB	HEK293_OSMI2_6hA	log2fold_HEK293_OSMI2_6hA_HEK293_TMG_6hB

ENSG00000183474	E001	0.1723744	0.0401548405	0.088210921		5	69560051	69560179	129	+	0.000	0.227	11.622
ENSG00000183474	E002	0.9043286	0.1865528358	1.000000000		5	69560180	69560190	11	+	0.242	0.228	-0.113
ENSG00000183474	E003	1.4687102	0.1890774369	0.622519752	0.78552397	5	69560191	69560207	17	+	0.368	0.224	-0.978
ENSG00000183474	E004	1.4687102	0.1890774369	0.622519752	0.78552397	5	69560208	69560208	1	+	0.368	0.224	-0.978
ENSG00000183474	E005	1.9341762	0.1117287568	0.367102212	0.60161897	5	69560209	69560222	14	+	0.446	0.225	-1.396
ENSG00000183474	E006	3.4156279	0.0074960265	0.058608350	0.19966390	5	69560223	69560224	2	+	0.622	0.227	-2.218
ENSG00000183474	E007	19.0146174	0.0023449609	0.448043343	0.66424432	5	69560225	69560241	17	+	1.188	1.258	0.249
ENSG00000183474	E008	21.2871276	0.0024154861	0.303321275	0.54388359	5	69560242	69560242	1	+	1.229	1.319	0.318
ENSG00000183474	E009	16.4805930	0.0025413916	0.134696311	0.33921363	5	69560243	69560246	4	+	1.114	1.258	0.515
ENSG00000183474	E010	24.8570635	0.0016524762	0.243450345	0.48047961	5	69560247	69560258	12	+	1.290	1.386	0.331
ENSG00000183474	E011	37.2897453	0.0012473779	0.028749159	0.12361112	5	69560259	69560293	35	+	1.450	1.595	0.497
ENSG00000183474	E012	40.4324676	0.0010656612	0.029930981	0.12713779	5	69560294	69560403	110	+	1.486	1.624	0.473
ENSG00000183474	E013	0.7664957	0.0193874923	0.256590734		5	69560404	69560601	198	+	0.163	0.375	1.589
ENSG00000183474	E014	0.0000000				5	69562652	69562672	21	+
ENSG00000183474	E015	21.5370744	0.0022607683	0.136421604	0.34201634	5	69562673	69562770	98	+	1.217	1.347	0.455
ENSG00000183474	E016	17.1467335	0.0021051122	0.879476620	0.94102687	5	69565100	69565121	22	+	1.162	1.146	-0.056
ENSG00000183474	E017	13.8506054	0.0028187348	0.429172346	0.65038984	5	69565122	69565132	11	+	1.088	0.996	-0.338
ENSG00000183474	E018	17.3233825	0.0022175510	0.457868833	0.67166515	5	69565133	69565188	56	+	1.180	1.102	-0.280
ENSG00000183474	E019	0.1779838	0.0350511252	1.000000000		5	69565369	69566130	762	+	0.061	0.000	-11.765
ENSG00000183474	E020	12.6371696	0.0028102692	0.882112776	0.94241747	5	69566131	69566208	78	+	1.036	1.052	0.059
ENSG00000183474	E021	0.4986023	0.0294956041	0.745875969		5	69566209	69566486	278	+	0.163	0.000	-13.287
ENSG00000183474	E022	9.1589235	0.0088465892	0.672919922	0.81817731	5	69566589	69566625	37	+	0.909	0.964	0.205
ENSG00000183474	E023	31.0322658	0.0018200431	0.755507956	0.86993679	5	69566967	69567053	87	+	1.411	1.385	-0.088
ENSG00000183474	E024	0.0000000				5	69567054	69567215	162	+
ENSG00000183474	E025	38.6906406	0.0010283876	0.227521165	0.46238793	5	69567727	69567777	51	+	1.509	1.421	-0.304
ENSG00000183474	E026	75.4260024	0.0009334779	0.056788907	0.19548841	5	69568153	69568207	55	+	1.796	1.695	-0.340
ENSG00000183474	E027	0.0000000				5	69568520	69570011	1492	+
ENSG00000183474	E028	118.2816146	0.0007709502	0.005298313	0.03618151	5	69572445	69572550	106	+	1.989	1.871	-0.397
ENSG00000183474	E029	0.0000000				5	69572551	69572844	294	+
ENSG00000183474	E030	62.5555396	0.0041959770	0.200241156	0.43002547	5	69578712	69578802	91	+	1.708	1.624	-0.286
ENSG00000183474	E031	0.7389688	0.0198145022	0.951194459		5	69578803	69579020	218	+	0.206	0.226	0.174
ENSG00000183474	E032	43.0304898	0.0008623003	0.913529551	0.95885737	5	69579021	69579108	88	+	1.539	1.530	-0.029
ENSG00000183474	E033	71.2316624	0.0009946556	0.889979925	0.94667223	5	69579757	69579864	108	+	1.751	1.741	-0.031
ENSG00000183474	E034	39.8117731	0.0014370445	0.759639888	0.87236186	5	69582366	69582429	64	+	1.507	1.484	-0.080
ENSG00000183474	E035	28.1850055	0.0018168178	0.384666360	0.61622311	5	69585594	69585697	104	+	1.342	1.410	0.235
ENSG00000183474	E036	9.3466987	0.0143759955	0.002392527	0.01963875	5	69586254	69586356	103	+	0.820	1.189	1.365
ENSG00000183474	E037	0.8040577	0.0213759471	0.259699957		5	69590328	69590367	40	+	0.163	0.375	1.586
ENSG00000183474	E038	0.6426420	0.0193874923	0.150598371		5	69592079	69592190	112	+	0.115	0.375	2.172
ENSG00000183474	E039	0.0000000				5	69592191	69592330	140	+
ENSG00000183474	E040	2.3847849	0.0090508926	0.419449997	0.64322946	5	69592331	69593472	1142	+	0.427	0.573	0.714
ENSG00000183474	E041	0.4820342	0.0213890649	0.743224869		5	69593473	69593705	233	+	0.163	0.000	-13.318
ENSG00000183474	E042	2.3680291	0.0098066393	0.165714586	0.38475533	5	69593706	69594243	538	+	0.401	0.646	1.174
ENSG00000183474	E043	7.4399332	0.0044038922	0.867287971	0.93447161	5	69594244	69595221	978	+	0.831	0.855	0.093
ENSG00000183474	E044	0.0000000				5	69600043	69600185	143	+
ENSG00000183474	E045	0.0000000				5	69603115	69603213	99	+

Isoforom Switch Analysis

WANG Ziyi

Date: 19 5月 2022

ENSG00000183474

1 Isoform Switch

TableFilter v0.7.3

2 Differential Exon Usage

TableFilter v0.7.3