ENSG00000180769

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000451762 ENSG00000180769 HEK293_OSMI2_6hA HEK293_TMG_6hB WDFY3-AS2 lncRNA lncRNA 0.4456498 0.3342712 0.4107383 0.03982937 0.009045395 0.2893775 0.09467584 0.1014683 0.06958862 0.01920189 0.02531366 -0.4860001 0.2283083 0.3008000 0.1675333 -0.1332667 0.73861985 0.01209685 TRUE FALSE
ENST00000651772 ENSG00000180769 HEK293_OSMI2_6hA HEK293_TMG_6hB WDFY3-AS2 lncRNA lncRNA 0.4456498 0.3342712 0.4107383 0.03982937 0.009045395 0.2893775 0.07396016 0.1034838 0.06620347 0.05920982 0.06620347 -0.5745576 0.1722833 0.3108333 0.1659667 -0.1448667 0.79366445 0.01209685 FALSE FALSE
ENST00000651964 ENSG00000180769 HEK293_OSMI2_6hA HEK293_TMG_6hB WDFY3-AS2 lncRNA lncRNA 0.4456498 0.3342712 0.4107383 0.03982937 0.009045395 0.2893775 0.06612897 0.0000000 0.06901358 0.00000000 0.06901358 2.9821005 0.1426958 0.0000000 0.1610667 0.1610667 0.87988161 0.01209685 FALSE FALSE
ENST00000652163 ENSG00000180769 HEK293_OSMI2_6hA HEK293_TMG_6hB WDFY3-AS2 lncRNA lncRNA 0.4456498 0.3342712 0.4107383 0.03982937 0.009045395 0.2893775 0.08739347 0.1080570 0.04643670 0.05428477 0.04643670 -1.0647776 0.2079417 0.3158667 0.1147333 -0.2011333 0.73861985 0.01209685 FALSE TRUE
ENST00000652490 ENSG00000180769 HEK293_OSMI2_6hA HEK293_TMG_6hB WDFY3-AS2 lncRNA lncRNA 0.4456498 0.3342712 0.4107383 0.03982937 0.009045395 0.2893775 0.07584115 0.0000000 0.12850282 0.00000000 0.01133623 3.7918434 0.1428875 0.0000000 0.3141667 0.3141667 0.01209685 0.01209685 TRUE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_6hB HEK293_OSMI2_6hA log2fold_HEK293_OSMI2_6hA_HEK293_TMG_6hB
ENSG00000180769 E001 0.0000000       4 84965534 84965563 30 +      
ENSG00000180769 E002 0.0000000       4 84965564 84965629 66 +      
ENSG00000180769 E003 0.0000000       4 84965630 84965648 19 +      
ENSG00000180769 E004 0.0000000       4 84965649 84965649 1 +      
ENSG00000180769 E005 0.0000000       4 84965650 84965656 7 +      
ENSG00000180769 E006 0.0000000       4 84965657 84965659 3 +      
ENSG00000180769 E007 0.0000000       4 84965660 84965681 22 +      
ENSG00000180769 E008 0.2027342 0.064369945 5.478326e-01   4 84965682 84965710 29 + 0.000 0.115 10.290
ENSG00000180769 E009 0.3336024 0.027442404 2.418613e-01   4 84965711 84965755 45 + 0.000 0.206 13.315
ENSG00000180769 E010 0.6839606 0.020542584 3.827223e-01   4 84965756 84965858 103 + 0.128 0.281 1.400
ENSG00000180769 E011 2.7044939 0.158560277 2.747539e-01 5.147403e-01 4 84966226 84966747 522 + 0.431 0.647 1.014
ENSG00000180769 E012 1.2449456 0.014153661 8.492543e-01   4 84966748 84966792 45 + 0.376 0.344 -0.185
ENSG00000180769 E013 1.1031187 0.017844977 1.894139e-01   4 84966793 84966808 16 + 0.434 0.206 -1.506
ENSG00000180769 E014 3.2798520 0.053639684 9.057280e-01 9.549893e-01 4 84966809 84966934 126 + 0.644 0.660 0.071
ENSG00000180769 E015 2.6719390 0.011681704 5.172710e-01 7.131742e-01 4 84966935 84966981 47 + 0.532 0.635 0.464
ENSG00000180769 E016 2.7139225 0.014324737 1.488364e-01 3.606594e-01 4 84966982 84967016 35 + 0.434 0.666 1.080
ENSG00000180769 E017 3.8860065 0.007491679 1.873752e-02 9.151482e-02 4 84967017 84967127 111 + 0.486 0.829 1.477
ENSG00000180769 E018 0.5059767 0.022817100 1.079226e-01   4 84967478 84967519 42 + 0.000 0.281 13.776
ENSG00000180769 E019 0.6071052 0.021768165 3.827941e-01   4 84967520 84967558 39 + 0.128 0.280 1.399
ENSG00000180769 E020 0.5767453 0.021058270 3.847112e-01   4 84967559 84967609 51 + 0.128 0.280 1.397
ENSG00000180769 E021 0.7844689 0.019836315 2.251820e-01   4 84967610 84967640 31 + 0.128 0.344 1.811
ENSG00000180769 E022 1.5226298 0.013787030 2.965178e-01 5.370219e-01 4 84969725 84969726 2 + 0.308 0.493 1.033
ENSG00000180769 E023 3.1287046 0.008024486 1.315191e-01 3.342106e-01 4 84969727 84969773 47 + 0.486 0.718 1.035
ENSG00000180769 E024 2.5331783 0.010231235 2.143135e-01 4.467333e-01 4 84969774 84969775 2 + 0.434 0.636 0.951
ENSG00000180769 E025 4.3662758 0.006504170 9.992097e-01 1.000000e+00 4 84969776 84969876 101 + 0.738 0.743 0.019
ENSG00000180769 E026 0.3336024 0.027442404 2.418613e-01   4 84985098 84986101 1004 + 0.000 0.206 13.315
ENSG00000180769 E027 0.0000000       4 84986102 84986105 4 +      
ENSG00000180769 E028 4.9519409 0.005770151 8.796233e-01 9.410921e-01 4 84986106 84987173 1068 + 0.765 0.788 0.094
ENSG00000180769 E029 0.5117739 0.025301028 4.909232e-01   4 85000691 85000765 75 + 0.228 0.115 -1.186
ENSG00000180769 E030 0.1779838 0.050231937 4.331251e-01   4 85002538 85002737 200 + 0.129 0.000 -13.214
ENSG00000180769 E031 1.5769707 0.013286824 3.648007e-03 2.718485e-02 4 85004230 85004327 98 + 0.612 0.115 -3.357
ENSG00000180769 E032 0.0000000       4 85005474 85005568 95 +      
ENSG00000180769 E033 0.2852693 0.115378181 1.960043e-01   4 85006007 85006011 5 + 0.226 0.000 -13.951
ENSG00000180769 E034 13.8335349 0.005258423 3.535474e-06 8.558585e-05 4 85006012 85011277 5266 + 1.335 0.962 -1.339