ENSG00000179029

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000316425 ENSG00000179029 HEK293_OSMI2_6hA HEK293_TMG_6hB TMEM107 protein_coding protein_coding 10.01178 12.13966 9.985175 0.8903751 3.898216 -0.2816119 1.4175242 2.762491 0.0000000 0.94726503 0.00000000 -8.1150391 0.13176667 0.22010000 0.00000000 -0.220100000 1.153733e-06 1.153733e-06 FALSE TRUE
ENST00000363593 ENSG00000179029 HEK293_OSMI2_6hA HEK293_TMG_6hB TMEM107 protein_coding snoRNA 10.01178 12.13966 9.985175 0.8903751 3.898216 -0.2816119 0.5147745 0.000000 4.1181962 0.00000000 4.11819619 8.6893677 0.02904167 0.00000000 0.23233333 0.232333333 8.506035e-01 1.153733e-06   FALSE
ENST00000431792 ENSG00000179029 HEK293_OSMI2_6hA HEK293_TMG_6hB TMEM107 protein_coding protein_coding 10.01178 12.13966 9.985175 0.8903751 3.898216 -0.2816119 1.3757013 1.077242 0.0000000 0.82633051 0.00000000 -6.7645294 0.13752500 0.08273333 0.00000000 -0.082733333 4.237002e-01 1.153733e-06   FALSE
ENST00000437139 ENSG00000179029 HEK293_OSMI2_6hA HEK293_TMG_6hB TMEM107 protein_coding protein_coding 10.01178 12.13966 9.985175 0.8903751 3.898216 -0.2816119 2.2781752 2.170978 1.9355277 0.14903121 0.09469719 -0.1648140 0.24217917 0.18260000 0.24386667 0.061266667 8.821300e-01 1.153733e-06 FALSE TRUE
ENST00000449985 ENSG00000179029 HEK293_OSMI2_6hA HEK293_TMG_6hB TMEM107 protein_coding protein_coding 10.01178 12.13966 9.985175 0.8903751 3.898216 -0.2816119 2.9629242 4.302708 2.5946280 0.36574456 0.15442070 -0.7275169 0.30310833 0.35410000 0.34746667 -0.006633333 9.817222e-01 1.153733e-06   FALSE
ENST00000532998 ENSG00000179029 HEK293_OSMI2_6hA HEK293_TMG_6hB TMEM107 protein_coding protein_coding 10.01178 12.13966 9.985175 0.8903751 3.898216 -0.2816119 0.6130053 0.716036 0.4959367 0.08860493 0.05474608 -0.5210843 0.06735833 0.06026667 0.06816667 0.007900000 1.000000e+00 1.153733e-06 FALSE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_6hB HEK293_OSMI2_6hA log2fold_HEK293_OSMI2_6hA_HEK293_TMG_6hB
ENSG00000179029 E001 39.156417 0.012106393 6.706528e-02 0.2185486767 17 8172457 8173236 780 - 1.648 1.504 -0.489
ENSG00000179029 E002 34.737158 0.005481287 3.927697e-05 0.0006780658 17 8173237 8173453 217 - 1.691 1.408 -0.967
ENSG00000179029 E003 35.156114 0.001199587 7.388404e-05 0.0011616711 17 8173454 8173741 288 - 1.673 1.430 -0.831
ENSG00000179029 E004 23.959614 0.002698412 5.907213e-02 0.2006923143 17 8173742 8173998 257 - 1.446 1.298 -0.513
ENSG00000179029 E005 10.702097 0.022634515 4.286460e-01 0.6500446205 17 8173999 8174000 2 - 1.086 0.987 -0.361
ENSG00000179029 E006 10.832965 0.019204375 4.544561e-01 0.6691012421 17 8174001 8174002 2 - 1.086 0.995 -0.334
ENSG00000179029 E007 43.896719 0.001669101 7.571094e-01 0.8709186893 17 8174003 8174101 99 - 1.581 1.598 0.059
ENSG00000179029 E008 63.814417 0.004837747 5.852299e-01 0.7604500436 17 8174102 8174170 69 - 1.725 1.755 0.102
ENSG00000179029 E009 81.906749 0.002405520 4.642658e-02 0.1710843735 17 8174171 8174272 102 - 1.781 1.877 0.321
ENSG00000179029 E010 7.556650 0.503110461 2.274579e-01 0.4623189841 17 8174273 8174519 247 - 1.001 0.821 -0.680
ENSG00000179029 E011 18.574540 0.215814331 5.594386e-01 0.7429215273 17 8174520 8174540 21 - 1.203 1.239 0.128
ENSG00000179029 E012 26.718150 0.071294160 7.230810e-01 0.8500037304 17 8174541 8174583 43 - 1.354 1.391 0.128
ENSG00000179029 E013 24.949757 0.180018987 8.395747e-01 0.9191535636 17 8174584 8174616 33 - 1.259 1.377 0.412
ENSG00000179029 E014 20.895188 0.018400510 1.406978e-01 0.3485896320 17 8174617 8175756 1140 - 1.378 1.238 -0.489
ENSG00000179029 E015 34.864003 0.005388780 9.095122e-04 0.0091741558 17 8175757 8175857 101 - 1.278 1.548 0.935
ENSG00000179029 E016 3.788679 0.132680292 1.579607e-01 0.3736746243 17 8175858 8175875 18 - 0.325 0.694 1.819
ENSG00000179029 E017 3.759417 0.203390702 9.717978e-02 0.2768172120 17 8175876 8175958 83 - 0.193 0.701 2.848
ENSG00000179029 E018 30.477567 0.001161842 2.974853e-03 0.0232435470 17 8175959 8176026 68 - 1.252 1.483 0.801
ENSG00000179029 E019 4.498096 0.113500177 6.719183e-01 0.8175291611 17 8176027 8176199 173 - 0.736 0.675 -0.252
ENSG00000179029 E020 81.937930 0.002370585 2.388397e-02 0.1087210037 17 8176200 8176399 200 - 1.773 1.882 0.367