ENSG00000171067

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000304271 ENSG00000171067 HEK293_OSMI2_6hA HEK293_TMG_6hB C11orf24 protein_coding protein_coding 50.6266 67.72955 29.74661 7.463746 1.209453 -1.186788 30.588586 44.255854 17.419362 4.5539132 1.0045777 -1.3446745 0.60433750 0.65466667 0.58486667 -0.06980000 0.24783061 0.02041686 FALSE  
ENST00000529590 ENSG00000171067 HEK293_OSMI2_6hA HEK293_TMG_6hB C11orf24 protein_coding processed_transcript 50.6266 67.72955 29.74661 7.463746 1.209453 -1.186788 5.109578 6.795514 1.947780 1.6324912 0.3523945 -1.7974854 0.09526250 0.09706667 0.06576667 -0.03130000 0.67155593 0.02041686 FALSE  
ENST00000533310 ENSG00000171067 HEK293_OSMI2_6hA HEK293_TMG_6hB C11orf24 protein_coding protein_coding 50.6266 67.72955 29.74661 7.463746 1.209453 -1.186788 3.418629 4.000726 1.215401 0.5396261 0.6079626 -1.7106094 0.06715833 0.05983333 0.04053333 -0.01930000 0.84068195 0.02041686 TRUE  
MSTRG.5851.3 ENSG00000171067 HEK293_OSMI2_6hA HEK293_TMG_6hB C11orf24 protein_coding   50.6266 67.72955 29.74661 7.463746 1.209453 -1.186788 8.820230 9.384497 6.447251 1.1192129 0.3275599 -0.5408958 0.17657917 0.13840000 0.21723333 0.07883333 0.02041686 0.02041686 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_6hB HEK293_OSMI2_6hA log2fold_HEK293_OSMI2_6hA_HEK293_TMG_6hB
ENSG00000171067 E001 3.195991 0.0072016286 0.06780586 0.22017197 11 68261338 68261373 36 - 0.218 0.606 2.219
ENSG00000171067 E002 16.516115 0.0022137474 0.38179299 0.61377015 11 68261374 68261435 62 - 1.221 1.134 -0.307
ENSG00000171067 E003 20.468240 0.0017461665 0.96726620 0.98560005 11 68261436 68261462 27 - 1.237 1.242 0.015
ENSG00000171067 E004 59.921830 0.0006390162 0.22282006 0.45680587 11 68261463 68261504 42 - 1.630 1.702 0.244
ENSG00000171067 E005 162.671441 0.1484415300 0.40681121 0.63361296 11 68261505 68261608 104 - 2.090 2.118 0.093
ENSG00000171067 E006 322.133095 0.4096123493 0.41675130 0.64120453 11 68261609 68261725 117 - 2.402 2.408 0.020
ENSG00000171067 E007 241.180221 0.2401358413 0.25862726 0.49744438 11 68261726 68261802 77 - 2.208 2.298 0.302
ENSG00000171067 E008 317.008526 0.3389520163 0.26837873 0.50804445 11 68261803 68261934 132 - 2.324 2.417 0.308
ENSG00000171067 E009 595.481925 0.8480688780 0.40386921 0.63140419 11 68261935 68262462 528 - 2.617 2.686 0.229
ENSG00000171067 E010 199.405075 0.1927069413 0.29045935 0.53112546 11 68262463 68262537 75 - 2.146 2.212 0.220
ENSG00000171067 E011 314.404300 0.3760897668 0.35617093 0.59268207 11 68262538 68262730 193 - 2.367 2.403 0.121
ENSG00000171067 E012 408.402799 0.7468197025 0.52321659 0.71724667 11 68262731 68262918 188 - 2.529 2.505 -0.081
ENSG00000171067 E013 12.481433 0.0558107079 0.89517212 0.94931131 11 68263245 68263355 111 - 1.054 1.034 -0.073
ENSG00000171067 E014 7.369360 0.0040755709 0.49621732 0.69834354 11 68263573 68263691 119 - 0.912 0.819 -0.356
ENSG00000171067 E015 191.988561 0.2158119566 0.41764224 0.64185754 11 68263692 68263714 23 - 2.171 2.187 0.052
ENSG00000171067 E016 331.986156 0.3965383041 0.36314850 0.59826374 11 68263715 68263866 152 - 2.393 2.427 0.113
ENSG00000171067 E017 10.567021 0.0182137018 0.85411023 0.92714723 11 68267101 68267179 79 - 0.945 0.987 0.157
ENSG00000171067 E018 45.617614 0.3142915777 0.29446651 0.53502797 11 68267180 68267397 218 - 1.690 1.533 -0.533
ENSG00000171067 E019 3.313653 0.0098250838 0.01804406 0.08918499 11 68267461 68267685 225 - 0.836 0.465 -1.612
ENSG00000171067 E020 1.701161 0.1296797987 0.59079616 0.76425027 11 68267740 68268053 314 - 0.468 0.356 -0.613
ENSG00000171067 E021 402.845642 0.2541436503 0.29900860 0.53945309 11 68268054 68268251 198 - 2.554 2.491 -0.212
ENSG00000171067 E022 3.113422 0.0110131362 0.22884360 0.46384641 11 68268252 68268278 27 - 0.691 0.488 -0.910
ENSG00000171067 E023 32.956385 0.3307175507 0.23851119 0.47490084 11 68271646 68271856 211 - 1.604 1.378 -0.773
ENSG00000171067 E024 177.988436 0.3219287181 0.54535734 0.73295869 11 68271857 68272001 145 - 2.164 2.148 -0.057