ENSG00000170364

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000358065 ENSG00000170364 HEK293_OSMI2_6hA HEK293_TMG_6hB SETMAR protein_coding protein_coding 7.84834 3.570394 9.918895 0.6736896 0.4543918 1.471515 2.2472878 1.0139273 3.5330715 0.14775935 0.20998890 1.79088727 0.27940000 0.29030000 0.35593333 0.06563333 0.58630607 0.03862174 FALSE TRUE
ENST00000425046 ENSG00000170364 HEK293_OSMI2_6hA HEK293_TMG_6hB SETMAR protein_coding nonsense_mediated_decay 7.84834 3.570394 9.918895 0.6736896 0.4543918 1.471515 2.4581590 1.2676590 2.5387567 0.64565928 0.37875506 0.99629088 0.30770000 0.29876667 0.26033333 -0.03843333 1.00000000 0.03862174 FALSE TRUE
ENST00000430981 ENSG00000170364 HEK293_OSMI2_6hA HEK293_TMG_6hB SETMAR protein_coding protein_coding 7.84834 3.570394 9.918895 0.6736896 0.4543918 1.471515 0.2341087 0.3316719 0.3360802 0.07079459 0.03481904 0.01849486 0.04360417 0.09216667 0.03383333 -0.05833333 0.03862174 0.03862174 FALSE TRUE
ENST00000490691 ENSG00000170364 HEK293_OSMI2_6hA HEK293_TMG_6hB SETMAR protein_coding processed_transcript 7.84834 3.570394 9.918895 0.6736896 0.4543918 1.471515 0.1371581 0.3005232 0.3355056 0.16400450 0.18847021 0.15400784 0.02542500 0.10870000 0.03250000 -0.07620000 0.88385782 0.03862174 FALSE TRUE
MSTRG.22401.1 ENSG00000170364 HEK293_OSMI2_6hA HEK293_TMG_6hB SETMAR protein_coding   7.84834 3.570394 9.918895 0.6736896 0.4543918 1.471515 1.2444877 0.1855477 1.6978810 0.09973145 0.08999869 3.12661524 0.15625417 0.07063333 0.17263333 0.10200000 0.38417960 0.03862174 FALSE TRUE
MSTRG.22401.4 ENSG00000170364 HEK293_OSMI2_6hA HEK293_TMG_6hB SETMAR protein_coding   7.84834 3.570394 9.918895 0.6736896 0.4543918 1.471515 0.9664465 0.1060949 0.6470925 0.10609487 0.64709246 2.50079222 0.11644167 0.04710000 0.05976667 0.01266667 0.97700982 0.03862174 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_6hB HEK293_OSMI2_6hA log2fold_HEK293_OSMI2_6hA_HEK293_TMG_6hB
ENSG00000170364 E001 0.3807181 0.0318164468 0.547594922   3 4303131 4303331 201 + 0.084 0.172 1.180
ENSG00000170364 E002 0.3807181 0.0318164468 0.547594922   3 4303332 4303336 5 + 0.084 0.172 1.181
ENSG00000170364 E003 1.2069534 0.2095828643 0.960111233   3 4303337 4303348 12 + 0.322 0.295 -0.177
ENSG00000170364 E004 1.5297848 0.1448657515 0.631092176 0.79110562 3 4303349 4303360 12 + 0.403 0.295 -0.654
ENSG00000170364 E005 1.8939347 0.2194790730 0.868310985 0.93504322 3 4303361 4303368 8 + 0.441 0.394 -0.250
ENSG00000170364 E006 1.8939347 0.2194790730 0.868310985 0.93504322 3 4303369 4303370 2 + 0.441 0.394 -0.250
ENSG00000170364 E007 15.6112171 0.0024933901 0.400164208 0.62840604 3 4303371 4303526 156 + 1.210 1.134 -0.272
ENSG00000170364 E008 1.0067919 0.0165221142 0.331181797   3 4303608 4303612 5 + 0.216 0.390 1.178
ENSG00000170364 E009 1.3515406 0.1291339179 0.098493562   3 4303613 4303626 14 + 0.217 0.538 1.921
ENSG00000170364 E010 4.7470616 0.0218258833 0.237051221 0.47315236 3 4303627 4303868 242 + 0.667 0.835 0.682
ENSG00000170364 E011 1.2790773 0.0131384066 0.235816137   3 4303869 4304090 222 + 0.398 0.172 -1.628
ENSG00000170364 E012 25.1192927 0.0015396537 0.929159553 0.96660620 3 4312898 4313229 332 + 1.391 1.385 -0.019
ENSG00000170364 E013 38.6879919 0.0010941166 0.912307770 0.95830349 3 4313230 4313646 417 + 1.566 1.573 0.024
ENSG00000170364 E014 16.1157350 0.0021246325 0.049667789 0.17883458 3 4313647 4313666 20 + 1.142 1.310 0.593
ENSG00000170364 E015 27.7668155 0.0066958449 0.151172337 0.36403590 3 4313667 4313761 95 + 1.393 1.499 0.365
ENSG00000170364 E016 7.1751225 0.0040825592 0.012203623 0.06726467 3 4313762 4314402 641 + 0.773 1.067 1.114
ENSG00000170364 E017 175.7638256 0.0004776355 0.008397522 0.05114925 3 4316212 4317265 1054 + 2.232 2.180 -0.175