• ENSG00000168067
  • 1 Isoform Switch
  • 2 Differential Exon Usage

ENSG00000168067

1 Isoform Switch

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

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isoform_idColumn filter
gene_idColumn filter
condition_1Column filter
condition_2Column filter
gene_nameColumn filter
gene_biotypeColumn filter
iso_biotypeColumn filter
gene_overall_meanColumn filter
gene_value_1Column filter
gene_value_2Column filter
gene_stderr_1Column filter
gene_stderr_2Column filter
gene_log2_fold_changeColumn filter
iso_overall_meanColumn filter
iso_value_1Column filter
iso_value_2Column filter
iso_stderr_1Column filter
iso_stderr_2Column filter
iso_log2_fold_changeColumn filter
IF_overallColumn filter
IF1Column filter
IF2Column filter
dIFColumn filter
isoform_switch_q_valueColumn filter
gene_switch_q_valueColumn filter
PTCColumn filter
codingPotentialColumn filter
ENST00000294066 ENSG00000168067 HEK293_OSMI2_6hA HEK293_TMG_6hB MAP4K2 protein_coding protein_coding 5.288762 6.586084 2.821211 1.119843 0.1312494 -1.220191 0.2816864 0.2433767 0.3025180 0.06672013 0.05882610 0.3026558 0.06646667 0.04170000 0.10690000 0.0652000 0.367643674 0.001143813 FALSE TRUE
ENST00000377350 ENSG00000168067 HEK293_OSMI2_6hA HEK293_TMG_6hB MAP4K2 protein_coding protein_coding 5.288762 6.586084 2.821211 1.119843 0.1312494 -1.220191 1.2786694 2.2977252 0.3541548 0.42981180 0.05669611 -2.6638477 0.22876250 0.34783333 0.12583333 -0.2220000 0.001143813 0.001143813 FALSE TRUE
ENST00000467689 ENSG00000168067 HEK293_OSMI2_6hA HEK293_TMG_6hB MAP4K2 protein_coding retained_intron 5.288762 6.586084 2.821211 1.119843 0.1312494 -1.220191 0.6084155 0.4185115 0.5394044 0.14432260 0.14016155 0.3585346 0.12962083 0.06900000 0.18780000 0.1188000 0.327987608 0.001143813 FALSE FALSE
ENST00000470088 ENSG00000168067 HEK293_OSMI2_6hA HEK293_TMG_6hB MAP4K2 protein_coding retained_intron 5.288762 6.586084 2.821211 1.119843 0.1312494 -1.220191 0.2810851 0.2200385 0.1481618 0.17681244 0.06511271 -0.5404740 0.06059583 0.04563333 0.05373333 0.0081000 0.805780531 0.001143813 FALSE TRUE
MSTRG.5683.3 ENSG00000168067 HEK293_OSMI2_6hA HEK293_TMG_6hB MAP4K2 protein_coding   5.288762 6.586084 2.821211 1.119843 0.1312494 -1.220191 2.3939632 2.9626466 0.8704691 0.73554239 0.35178079 -1.7554037 0.41835833 0.43686667 0.30110000 -0.1357667 0.773367887 0.001143813 FALSE TRUE
MSTRG.5683.4 ENSG00000168067 HEK293_OSMI2_6hA HEK293_TMG_6hB MAP4K2 protein_coding   5.288762 6.586084 2.821211 1.119843 0.1312494 -1.220191 0.1510223 0.2808923 0.3899909 0.16771692 0.38999095 0.4594822 0.03830833 0.03593333 0.14776667 0.1118333 0.922857932 0.001143813 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

All exons whithin this gene region are shown and numbering below.

All exons whithin this gene region are shown and numbering below.

All exons whithin this gene region are shown and numbering below.

All isoforms whithin this gene region are shown below.

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groupIDColumn filter
featureIDColumn filter
exonBaseMeanColumn filter
dispersionColumn filter
pvalueColumn filter
padjColumn filter
seqnamesColumn filter
startColumn filter
endColumn filter
widthColumn filter
strandColumn filter
HEK293_TMG_6hBColumn filter
HEK293_OSMI2_6hAColumn filter
log2fold_HEK293_OSMI2_6hA_HEK293_TMG_6hBColumn filter
ENSG00000168067 E001 26.6077552 0.0997836664 6.234328e-03 0.0408824300 11 64784918 64788817 3900 - 1.679 1.207 -1.627
ENSG00000168067 E002 3.5234175 0.1851732780 4.624642e-02 0.1706473971 11 64788818 64789136 319 - 0.902 0.445 -1.969
ENSG00000168067 E003 53.6689966 0.0008565967 3.237076e-01 0.5630113983 11 64789137 64789536 400 - 1.639 1.683 0.148
ENSG00000168067 E004 39.6740175 0.0021827901 3.883629e-01 0.6191578694 11 64789537 64789624 88 - 1.506 1.550 0.151
ENSG00000168067 E005 30.9328265 0.0012221897 7.274559e-01 0.8527439274 11 64789730 64789785 56 - 1.429 1.443 0.048
ENSG00000168067 E006 37.4312796 0.0010512357 9.650332e-01 0.9844597609 11 64789889 64789959 71 - 1.529 1.521 -0.027
ENSG00000168067 E007 36.1222333 0.0011287334 4.294443e-01 0.6506041000 11 64790188 64790274 87 - 1.550 1.487 -0.218
ENSG00000168067 E008 25.3698046 0.0015310796 9.146387e-01 0.9594226681 11 64790394 64790450 57 - 1.370 1.349 -0.071
ENSG00000168067 E009 16.8593587 0.0032148367 3.368571e-01 0.5752376777 11 64790451 64790462 12 - 1.262 1.163 -0.350
ENSG00000168067 E010 22.4611557 0.0019956513 1.880322e-01 0.4144670611 11 64791909 64791957 49 - 1.233 1.337 0.366
ENSG00000168067 E011 25.3590274 0.0015711515 1.177349e-05 0.0002412415 11 64791958 64792086 129 - 1.032 1.431 1.411
ENSG00000168067 E012 1.1824903 0.8092474972 6.177819e-01   11 64792087 64792171 85 - 0.333 0.288 -0.290
ENSG00000168067 E013 22.3936046 0.0017539777 6.925820e-03 0.0442966087 11 64792172 64792275 104 - 1.116 1.352 0.834
ENSG00000168067 E014 0.8759238 0.0327352122 1.029274e-01   11 64792276 64792363 88 - 0.436 0.135 -2.250
ENSG00000168067 E015 24.2136092 0.0031855102 2.422989e-01 0.4791217024 11 64792364 64792422 59 - 1.275 1.362 0.303
ENSG00000168067 E016 33.2475326 0.0015359459 4.665273e-02 0.1717027308 11 64796273 64796390 118 - 1.370 1.503 0.461
ENSG00000168067 E017 23.0379392 0.0173170462 5.424166e-02 0.1896380937 11 64796493 64796553 61 - 1.170 1.358 0.661
ENSG00000168067 E018 27.7739999 0.0015054043 3.420262e-02 0.1394036312 11 64796634 64796713 80 - 1.275 1.434 0.554
ENSG00000168067 E019 29.1677169 0.0014033653 1.513299e-01 0.3642847292 11 64796809 64796893 85 - 1.337 1.435 0.341
ENSG00000168067 E020 0.1426347 0.0334224030 1.520296e-01   11 64796971 64796981 11 - 0.197 0.000 -11.526
ENSG00000168067 E021 22.7012441 0.0015040367 2.959575e-02 0.1261517641 11 64796982 64797023 42 - 1.170 1.352 0.640
ENSG00000168067 E022 24.7495391 0.0015740118 6.501295e-03 0.0422109408 11 64797104 64797168 65 - 1.170 1.395 0.790
ENSG00000168067 E023 10.9207887 0.0036814235 9.829911e-01 0.9932771126 11 64797169 64797192 24 - 1.032 1.024 -0.030
ENSG00000168067 E024 25.3128859 0.0017313977 2.070656e-01 0.4382750988 11 64797275 64797380 106 - 1.288 1.379 0.318
ENSG00000168067 E025 3.9385594 0.0147508252 4.244443e-02 0.1611131369 11 64797381 64797500 120 - 0.865 0.547 -1.326
ENSG00000168067 E026 16.3039986 0.0024708326 4.139032e-01 0.6389155122 11 64797501 64797534 34 - 1.247 1.162 -0.301
ENSG00000168067 E027 22.0681459 0.0072138629 8.434377e-01 0.9213423169 11 64797626 64797664 39 - 1.325 1.301 -0.085
ENSG00000168067 E028 26.6262206 0.0148709584 6.088855e-01 0.7761455122 11 64798794 64798837 44 - 1.419 1.365 -0.188
ENSG00000168067 E029 30.0004215 0.0052868801 1.266551e-01 0.3265031122 11 64799421 64799479 59 - 1.521 1.397 -0.428
ENSG00000168067 E030 28.6258158 0.0013544393 9.881230e-01 0.9958872964 11 64799605 64799683 79 - 1.420 1.411 -0.032
ENSG00000168067 E031 28.1874803 0.0019434281 1.397860e-01 0.3471459626 11 64800109 64800181 73 - 1.490 1.370 -0.414
ENSG00000168067 E032 21.0057932 0.0017594563 1.454895e-02 0.0764345582 11 64800182 64800216 35 - 1.429 1.223 -0.719
ENSG00000168067 E033 17.5427486 0.0020406384 2.298884e-02 0.1059123266 11 64800311 64800335 25 - 1.359 1.152 -0.728
ENSG00000168067 E034 15.0013881 0.0023002370 1.513683e-02 0.0786048747 11 64800336 64800347 12 - 1.313 1.080 -0.827
ENSG00000168067 E035 20.4242487 0.0018975185 2.890011e-02 0.1240642277 11 64800348 64800392 45 - 1.410 1.223 -0.654
ENSG00000168067 E036 19.5846695 0.0020845772 1.411253e-02 0.0747919064 11 64800764 64800799 36 - 1.410 1.199 -0.739
ENSG00000168067 E037 18.1569882 0.0022037104 1.101559e-01 0.2992402264 11 64800800 64800826 27 - 1.336 1.189 -0.520
ENSG00000168067 E038 17.3181401 0.0025146108 1.170995e-01 0.3109977269 11 64800900 64801031 132 - 1.097 1.241 0.514
ENSG00000168067 E039 28.6101757 0.0174822285 1.759329e-01 0.3983554066 11 64801111 64801183 73 - 1.312 1.433 0.418
ENSG00000168067 E040 20.3672611 0.0838303944 8.004603e-01 0.8965787137 11 64801579 64801621 43 - 1.256 1.267 0.037
ENSG00000168067 E041 20.2676215 0.0022112915 9.633271e-01 0.9836105549 11 64801710 64801757 48 - 1.275 1.260 -0.053
ENSG00000168067 E042 0.1426347 0.0334224030 1.520296e-01   11 64801758 64801813 56 - 0.197 0.000 -11.526
ENSG00000168067 E043 19.6937050 0.0044904436 8.923307e-01 0.9477836379 11 64802066 64802121 56 - 1.247 1.247 -0.001
ENSG00000168067 E044 19.4971962 0.0387263419 9.113940e-01 0.9579088865 11 64802419 64802483 65 - 1.247 1.240 -0.022
ENSG00000168067 E045 18.3549718 0.0195032692 6.200386e-01 0.7838549982 11 64802563 64802627 65 - 1.187 1.225 0.136
ENSG00000168067 E046 10.9904968 0.0037129829 9.193419e-01 0.9618981134 11 64802628 64802630 3 - 1.032 1.010 -0.083
ENSG00000168067 E047 14.1164798 0.0414156378 7.563095e-01 0.8704111760 11 64802631 64802653 23 - 1.153 1.095 -0.208
ENSG00000168067 E048 14.6937751 0.0715585983 7.655512e-01 0.8760010914 11 64802885 64802942 58 - 1.173 1.109 -0.228
ENSG00000168067 E049 0.7379733 0.0188685844 8.327822e-01   11 64802943 64803053 111 - 0.197 0.236 0.330
ENSG00000168067 E050 9.3728431 0.0033831405 9.583467e-01 0.9810573346 11 64803054 64803241 188 - 0.957 0.952 -0.016