ENSG00000167182

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000376741 ENSG00000167182 HEK293_OSMI2_6hA HEK293_TMG_6hB SP2 protein_coding protein_coding 9.733065 11.49452 9.474941 1.997893 0.4384739 -0.2784906 8.1978608 9.9713199 7.0564316 1.7594118 0.49506635 -0.4982487 0.8364917 0.86666667 0.7444 -0.12226667 9.069910e-02 8.307603e-06 FALSE TRUE
ENST00000637314 ENSG00000167182 HEK293_OSMI2_6hA HEK293_TMG_6hB SP2 protein_coding protein_coding 9.733065 11.49452 9.474941 1.997893 0.4384739 -0.2784906 0.4200047 0.2097402 0.9757718 0.2097402 0.08424144 2.1654550 0.0482000 0.01493333 0.1037 0.08876667 1.650530e-01 8.307603e-06 FALSE TRUE
MSTRG.14573.2 ENSG00000167182 HEK293_OSMI2_6hA HEK293_TMG_6hB SP2 protein_coding   9.733065 11.49452 9.474941 1.997893 0.4384739 -0.2784906 0.3263613 0.5812995 0.0000000 0.1801549 0.00000000 -5.8858173 0.0313750 0.05003333 0.0000 -0.05003333 8.307603e-06 8.307603e-06 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_6hB HEK293_OSMI2_6hA log2fold_HEK293_OSMI2_6hA_HEK293_TMG_6hB
ENSG00000167182 E001 0.3807181 0.0351416217 0.722995516   17 47896150 47896181 32 + 0.150 0.098 -0.707
ENSG00000167182 E002 1.5113636 0.0126221929 0.297051407 0.53749612 17 47896182 47896235 54 + 0.486 0.303 -1.029
ENSG00000167182 E003 1.3333798 0.0134184545 0.501634381   17 47896236 47896236 1 + 0.423 0.303 -0.706
ENSG00000167182 E004 12.6867019 0.0033714985 0.293650983 0.53430827 17 47896237 47896261 25 + 1.069 1.171 0.369
ENSG00000167182 E005 23.7897173 0.0053121678 0.832483854 0.91519385 17 47896262 47896293 32 + 1.382 1.399 0.060
ENSG00000167182 E006 0.1308682 0.0326491905 0.746163084   17 47896294 47896337 44 + 0.000 0.098 8.689
ENSG00000167182 E007 8.4262518 0.0066870292 0.774070663 0.88118382 17 47897815 47897927 113 + 0.947 0.980 0.126
ENSG00000167182 E008 0.8619444 0.0357729513 0.927981529   17 47908600 47908697 98 + 0.262 0.245 -0.126
ENSG00000167182 E009 2.2551341 0.0090992311 0.154262156 0.36835296 17 47909664 47909730 67 + 0.633 0.400 -1.125
ENSG00000167182 E010 0.6368449 0.0189502287 0.104098403   17 47914726 47914861 136 + 0.000 0.303 10.774
ENSG00000167182 E011 41.0819390 0.0122718673 0.349792630 0.58707327 17 47915312 47915388 77 + 1.661 1.593 -0.232
ENSG00000167182 E012 291.2525212 0.0002531550 0.001445074 0.01322662 17 47916156 47917130 975 + 2.492 2.433 -0.199
ENSG00000167182 E013 123.6672367 0.0003367976 0.776071215 0.88239060 17 47922962 47923274 313 + 2.081 2.090 0.029
ENSG00000167182 E014 98.7011492 0.0004986549 0.940848412 0.97267663 17 47924919 47925093 175 + 1.989 1.991 0.008
ENSG00000167182 E015 96.4777740 0.0004116988 0.519471825 0.71467092 17 47925348 47925541 194 + 1.964 1.987 0.076
ENSG00000167182 E016 73.0640933 0.0041800979 0.794612394 0.89310342 17 47927724 47927820 97 + 1.849 1.858 0.031
ENSG00000167182 E017 112.6476384 0.0006717505 0.076820638 0.23842519 17 47927821 47928153 333 + 2.005 2.065 0.202
ENSG00000167182 E018 170.2066182 0.0003401297 0.035331260 0.14244003 17 47928154 47928935 782 + 2.186 2.242 0.187
ENSG00000167182 E019 6.7774904 0.0046513967 0.535216954 0.72572638 17 47928936 47928965 30 + 0.831 0.907 0.292
ENSG00000167182 E020 3.8390313 0.0063269547 0.721691034 0.84912196 17 47928966 47929060 95 + 0.709 0.656 -0.223
ENSG00000167182 E021 1.1789786 0.0145217570 0.607925919   17 47929061 47929338 278 + 0.261 0.355 0.613
ENSG00000167182 E022 1.1613130 0.0630822028 0.980029343   17 47929662 47929733 72 + 0.349 0.351 0.009
ENSG00000167182 E023 10.3390404 0.0033890364 0.164776819 0.38371102 17 47929734 47930247 514 + 1.126 0.982 -0.527