ENSG00000166783

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000396368 ENSG00000166783 HEK293_OSMI2_6hA HEK293_TMG_6hB MARF1 protein_coding protein_coding 8.343196 8.7558 11.3637 1.945906 0.7138667 0.3757446 4.2217093 4.6017045 6.8849736 0.9528462 0.3636675 0.5802449 0.4956542 0.5285667 0.60690000 0.07833333 0.44924657 0.01025784 FALSE TRUE
ENST00000540441 ENSG00000166783 HEK293_OSMI2_6hA HEK293_TMG_6hB MARF1 protein_coding protein_coding 8.343196 8.7558 11.3637 1.945906 0.7138667 0.3757446 0.2664716 0.4694176 0.0000000 0.4694176 0.0000000 -5.5832109 0.0336000 0.0562000 0.00000000 -0.05620000 0.85127321 0.01025784 FALSE TRUE
ENST00000552771 ENSG00000166783 HEK293_OSMI2_6hA HEK293_TMG_6hB MARF1 protein_coding retained_intron 8.343196 8.7558 11.3637 1.945906 0.7138667 0.3757446 1.5911440 1.7773856 0.9680825 0.4562970 0.0582252 -0.8698229 0.2114292 0.2030333 0.08616667 -0.11686667 0.01025784 0.01025784   FALSE
MSTRG.12139.7 ENSG00000166783 HEK293_OSMI2_6hA HEK293_TMG_6hB MARF1 protein_coding   8.343196 8.7558 11.3637 1.945906 0.7138667 0.3757446 0.9514177 0.5520344 1.4706698 0.2096888 0.3513002 1.3975197 0.1119333 0.0668000 0.12950000 0.06270000 0.61763372 0.01025784 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_6hB HEK293_OSMI2_6hA log2fold_HEK293_OSMI2_6hA_HEK293_TMG_6hB
ENSG00000166783 E001 1.1969022 0.0668122560 6.058517e-01   16 15594387 15594387 1 - 0.280 0.379 0.620
ENSG00000166783 E002 506.2356708 0.0018433728 2.302132e-10 1.511813e-08 16 15594388 15596170 1783 - 2.622 2.777 0.517
ENSG00000166783 E003 141.5758321 0.0003207574 9.568291e-03 5.626050e-02 16 15596171 15596634 464 - 2.108 2.196 0.294
ENSG00000166783 E004 28.4446198 0.0087413740 3.737289e-01 6.071262e-01 16 15596635 15596641 7 - 1.436 1.515 0.269
ENSG00000166783 E005 35.2954239 0.0122880086 5.151360e-01 7.117272e-01 16 15596642 15596692 51 - 1.535 1.596 0.208
ENSG00000166783 E006 56.2389895 0.0008880540 1.104846e-01 2.997591e-01 16 15596693 15596766 74 - 1.715 1.803 0.295
ENSG00000166783 E007 70.5160095 0.0008881591 3.732782e-02 1.478168e-01 16 15596767 15596937 171 - 1.800 1.901 0.341
ENSG00000166783 E008 52.6888644 0.0009326665 3.022929e-01 5.428862e-01 16 15598854 15598921 68 - 1.699 1.761 0.208
ENSG00000166783 E009 52.3341727 0.0168755225 5.499900e-01 7.362406e-01 16 15598922 15599024 103 - 1.698 1.755 0.191
ENSG00000166783 E010 5.7373739 0.1220999407 7.437932e-01 8.628599e-01 16 15599025 15599117 93 - 0.772 0.853 0.320
ENSG00000166783 E011 2.3272899 0.0992554305 4.030274e-01 6.307532e-01 16 15599118 15599171 54 - 0.402 0.583 0.891
ENSG00000166783 E012 49.5501440 0.0008706661 2.779620e-01 5.180401e-01 16 15600428 15600553 126 - 1.667 1.732 0.220
ENSG00000166783 E013 1.7274571 0.1182014838 8.468856e-01 9.232293e-01 16 15600554 15600640 87 - 0.401 0.441 0.211
ENSG00000166783 E014 35.9792108 0.0009432512 9.570509e-01 9.803912e-01 16 15600641 15600701 61 - 1.562 1.569 0.025
ENSG00000166783 E015 14.1273301 0.0983668475 4.125417e-01 6.379870e-01 16 15600702 15601863 1162 - 1.238 1.101 -0.490
ENSG00000166783 E016 59.8443916 0.0006623348 5.526737e-01 7.381575e-01 16 15601991 15602127 137 - 1.765 1.803 0.127
ENSG00000166783 E017 56.1022121 0.0008336423 2.300341e-01 4.651869e-01 16 15602128 15602203 76 - 1.723 1.791 0.229
ENSG00000166783 E018 94.1579506 0.0018566804 6.973493e-01 8.338326e-01 16 15604168 15604398 231 - 1.984 1.979 -0.017
ENSG00000166783 E019 0.1723744 0.0452097346 4.395407e-01   16 15605848 15606114 267 - 0.000 0.128 8.874
ENSG00000166783 E020 74.7057646 0.0345028280 7.034941e-01 8.378473e-01 16 15608291 15608518 228 - 1.865 1.895 0.101
ENSG00000166783 E021 75.4527630 0.0170222444 3.980744e-01 6.267942e-01 16 15609523 15609725 203 - 1.852 1.915 0.212
ENSG00000166783 E022 39.8760579 0.0010207854 9.263628e-01 9.652933e-01 16 15610975 15611029 55 - 1.600 1.615 0.052
ENSG00000166783 E023 44.3353142 0.0008120471 3.543095e-01 5.911238e-01 16 15611030 15611108 79 - 1.625 1.685 0.202
ENSG00000166783 E024 58.4499102 0.0008664614 8.733031e-01 9.377909e-01 16 15611592 15611734 143 - 1.759 1.777 0.061
ENSG00000166783 E025 62.7459766 0.0008989128 2.323708e-01 4.679622e-01 16 15612557 15612705 149 - 1.819 1.774 -0.149
ENSG00000166783 E026 43.1551769 0.0028426645 9.438198e-03 5.569754e-02 16 15612706 15612777 72 - 1.705 1.562 -0.486
ENSG00000166783 E027 61.4848299 0.0013164995 4.903984e-02 1.772893e-01 16 15615830 15616005 176 - 1.828 1.746 -0.278
ENSG00000166783 E028 0.4812263 0.0215978011 5.112297e-01   16 15616785 15617051 267 - 0.115 0.227 1.178
ENSG00000166783 E029 45.0823597 0.0016410078 2.558898e-02 1.140304e-01 16 15617052 15617171 120 - 1.710 1.600 -0.374
ENSG00000166783 E030 0.9809964 0.0792548101 5.374635e-01   16 15617172 15617298 127 - 0.344 0.229 -0.800
ENSG00000166783 E031 45.6037076 0.0151385144 3.525002e-01 5.895455e-01 16 15617299 15617535 237 - 1.690 1.643 -0.161
ENSG00000166783 E032 7.2843965 0.0328430205 2.657336e-02 1.169990e-01 16 15619552 15619706 155 - 1.029 0.714 -1.214
ENSG00000166783 E033 21.0473925 0.0020192218 5.769649e-01 7.550994e-01 16 15620451 15620531 81 - 1.358 1.328 -0.107
ENSG00000166783 E034 1.4167724 0.0126787783 8.492949e-01 9.245382e-01 16 15621493 15621732 240 - 0.401 0.375 -0.145
ENSG00000166783 E035 39.8874471 0.0011702624 4.336075e-02 1.634805e-01 16 15621733 15621911 179 - 1.658 1.556 -0.348
ENSG00000166783 E036 42.4578259 0.0054101467 1.265279e-01 3.263074e-01 16 15622934 15623057 124 - 1.668 1.584 -0.285
ENSG00000166783 E037 27.6989495 0.0024964415 4.946339e-01 6.972031e-01 16 15623058 15623096 39 - 1.465 1.429 -0.126
ENSG00000166783 E038 17.8897578 0.0019175874 1.539667e-01 3.679957e-01 16 15623097 15623123 27 - 1.322 1.216 -0.371
ENSG00000166783 E039 2.0712511 0.0468163446 4.132140e-01 6.385248e-01 16 15623124 15623126 3 - 0.570 0.431 -0.676
ENSG00000166783 E040 1.2555443 0.0136968632 5.732499e-01   16 15623127 15623150 24 - 0.401 0.307 -0.559
ENSG00000166783 E041 42.5090282 0.0119895045 8.918418e-01 9.475291e-01 16 15624769 15624927 159 - 1.638 1.636 -0.007
ENSG00000166783 E042 37.7851972 0.0262186630 8.760581e-01 9.392539e-01 16 15625016 15625173 158 - 1.586 1.595 0.033
ENSG00000166783 E043 63.3554065 0.0009712023 1.872323e-02 9.146667e-02 16 15625372 15625797 426 - 1.848 1.751 -0.327
ENSG00000166783 E044 12.0639468 0.0292166187 3.641603e-01 5.991438e-01 16 15625798 15625800 3 - 1.160 1.052 -0.387
ENSG00000166783 E045 0.1779838 0.0366760617 5.396093e-01   16 15630234 15630331 98 - 0.115 0.000 -9.530
ENSG00000166783 E046 34.1255660 0.0086930416 1.198806e-01 3.156744e-01 16 15630332 15630504 173 - 1.591 1.488 -0.355
ENSG00000166783 E047 30.7695653 0.0023985686 5.635914e-02 1.944709e-01 16 15631381 15631498 118 - 1.558 1.443 -0.393
ENSG00000166783 E048 40.5768869 0.0061636267 8.220175e-03 5.034350e-02 16 15633617 15633834 218 - 1.692 1.529 -0.557
ENSG00000166783 E049 14.8174644 0.0198901243 1.868829e-01 4.128903e-01 16 15633835 15633843 9 - 1.256 1.133 -0.437
ENSG00000166783 E050 41.1394357 0.0111427222 1.121325e-05 2.314656e-04 16 15634757 15634931 175 - 1.749 1.426 -1.102
ENSG00000166783 E051 0.8018448 0.0240376104 7.397282e-01   16 15634932 15635655 724 - 0.281 0.227 -0.407
ENSG00000166783 E052 63.6812946 0.0006128737 4.284706e-08 1.735498e-06 16 15635656 15635993 338 - 1.905 1.666 -0.808
ENSG00000166783 E053 23.0785895 0.0016436005 3.794995e-02 1.494960e-01 16 15635994 15636045 52 - 1.446 1.306 -0.487
ENSG00000166783 E054 59.1124402 0.0078832410 2.529197e-03 2.052350e-02 16 15636046 15636342 297 - 1.856 1.676 -0.607
ENSG00000166783 E055 39.3622941 0.0043158389 8.570792e-02 2.558717e-01 16 15639090 15639291 202 - 1.650 1.552 -0.336
ENSG00000166783 E056 0.3337900 0.0340710251 9.367515e-01   16 15642459 15642488 30 - 0.115 0.128 0.182
ENSG00000166783 E057 5.4230164 0.0048486139 9.587318e-01 9.812667e-01 16 15643018 15643154 137 - 0.810 0.812 0.010