ENSG00000165802

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000265663 ENSG00000165802 HEK293_OSMI2_6hA HEK293_TMG_6hB NSMF protein_coding protein_coding 91.18757 130.8988 68.06011 19.03517 2.590383 -0.9434687 54.442511 86.3969635 29.352489 15.8018783 0.3872590 -1.55717331 0.55464167 0.651333333 0.43210000 -0.2192333333 0.001440322 0.001440322 FALSE TRUE
ENST00000371468 ENSG00000165802 HEK293_OSMI2_6hA HEK293_TMG_6hB NSMF protein_coding retained_intron 91.18757 130.8988 68.06011 19.03517 2.590383 -0.9434687 4.582471 5.3127069 4.962378 1.6137546 0.3638600 -0.09822403 0.05789583 0.046700000 0.07290000 0.0262000000 0.626337187 0.001440322 FALSE TRUE
ENST00000371472 ENSG00000165802 HEK293_OSMI2_6hA HEK293_TMG_6hB NSMF protein_coding protein_coding 91.18757 130.8988 68.06011 19.03517 2.590383 -0.9434687 4.856928 0.7230499 9.606719 0.7230499 0.9679347 3.71356150 0.08018333 0.007666667 0.14050000 0.1328333333 0.053497737 0.001440322 FALSE TRUE
ENST00000371474 ENSG00000165802 HEK293_OSMI2_6hA HEK293_TMG_6hB NSMF protein_coding protein_coding 91.18757 130.8988 68.06011 19.03517 2.590383 -0.9434687 12.175979 18.9452061 6.433369 3.0598908 0.1820805 -1.55670705 0.12411250 0.143900000 0.09476667 -0.0491333333 0.013431970 0.001440322 FALSE TRUE
ENST00000482448 ENSG00000165802 HEK293_OSMI2_6hA HEK293_TMG_6hB NSMF protein_coding protein_coding 91.18757 130.8988 68.06011 19.03517 2.590383 -0.9434687 1.834962 0.2403807 6.658875 0.2403807 0.9687415 4.73524788 0.02571250 0.002566667 0.09723333 0.0946666667 0.015938812 0.001440322 FALSE FALSE
MSTRG.33709.10 ENSG00000165802 HEK293_OSMI2_6hA HEK293_TMG_6hB NSMF protein_coding   91.18757 130.8988 68.06011 19.03517 2.590383 -0.9434687 4.376170 8.4709873 4.105384 3.0088041 0.5419626 -1.04320503 0.05357917 0.060233333 0.06006667 -0.0001666667 0.983066796 0.001440322 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_6hB HEK293_OSMI2_6hA log2fold_HEK293_OSMI2_6hA_HEK293_TMG_6hB
ENSG00000165802 E001 6.605161 1.371625e-02 6.674586e-01 8.146107e-01 9 137447570 137447572 3 - 0.872 0.809 -0.241
ENSG00000165802 E002 160.762980 2.751762e-04 1.036610e-03 1.018638e-02 9 137447573 137448044 472 - 2.072 2.184 0.376
ENSG00000165802 E003 80.783483 5.225450e-03 2.211157e-04 2.905713e-03 9 137448045 137448224 180 - 1.684 1.908 0.755
ENSG00000165802 E004 52.586028 7.558517e-04 9.820879e-05 1.473201e-03 9 137448225 137448231 7 - 1.492 1.730 0.810
ENSG00000165802 E005 86.261184 4.507076e-04 4.705811e-06 1.091891e-04 9 137448232 137448286 55 - 1.720 1.939 0.736
ENSG00000165802 E006 856.236405 3.036293e-03 1.006488e-04 1.503352e-03 9 137448287 137448706 420 - 2.785 2.906 0.404
ENSG00000165802 E007 916.623360 6.874417e-04 1.355381e-08 6.165950e-07 9 137448707 137449041 335 - 2.828 2.935 0.355
ENSG00000165802 E008 1285.690016 8.273377e-05 8.418627e-14 1.062956e-11 9 137449042 137449390 349 - 2.987 3.078 0.302
ENSG00000165802 E009 1067.860777 9.035559e-05 1.230482e-01 3.205757e-01 9 137449391 137449491 101 - 2.959 2.981 0.073
ENSG00000165802 E010 640.515978 1.117937e-03 4.149550e-01 6.397827e-01 9 137449599 137449606 8 - 2.766 2.748 -0.061
ENSG00000165802 E011 714.533724 6.693606e-04 3.827816e-01 6.145360e-01 9 137449607 137449636 30 - 2.813 2.796 -0.054
ENSG00000165802 E012 744.401696 3.804055e-04 2.567622e-01 4.955312e-01 9 137449637 137449674 38 - 2.832 2.814 -0.061
ENSG00000165802 E013 628.175243 1.341100e-04 3.050606e-04 3.781482e-03 9 137449923 137449934 12 - 2.787 2.731 -0.183
ENSG00000165802 E014 989.648179 3.227917e-04 3.125653e-04 3.856494e-03 9 137449935 137450025 91 - 2.978 2.927 -0.170
ENSG00000165802 E015 2.769048 2.065013e-01 2.289077e-01 4.638891e-01 9 137450026 137450100 75 - 0.724 0.442 -1.281
ENSG00000165802 E016 977.418290 8.339042e-04 2.016421e-02 9.646316e-02 9 137450176 137450255 80 - 2.966 2.923 -0.143
ENSG00000165802 E017 1011.876364 1.753056e-04 1.258594e-05 2.560659e-04 9 137452365 137452435 71 - 2.992 2.936 -0.189
ENSG00000165802 E018 17.475160 6.834165e-02 1.472235e-02 7.704046e-02 9 137452465 137452552 88 - 1.444 1.090 -1.247
ENSG00000165802 E019 829.980384 1.903071e-04 4.835103e-11 3.654257e-09 9 137452553 137452586 34 - 2.933 2.840 -0.310
ENSG00000165802 E020 37.644577 1.213918e-01 4.809707e-02 1.752111e-01 9 137452587 137452735 149 - 1.743 1.424 -1.090
ENSG00000165802 E021 978.917336 9.503915e-05 6.782862e-08 2.623288e-06 9 137452736 137452819 84 - 2.986 2.920 -0.222
ENSG00000165802 E022 42.208649 1.023890e-01 1.350940e-01 3.398480e-01 9 137452820 137453055 236 - 1.733 1.510 -0.759
ENSG00000165802 E023 996.393765 1.737239e-04 6.916157e-04 7.372560e-03 9 137453056 137453180 125 - 2.977 2.934 -0.143
ENSG00000165802 E024 46.936679 9.082331e-02 1.699400e-01 3.903840e-01 9 137453181 137453730 550 - 1.764 1.564 -0.680
ENSG00000165802 E025 646.758331 2.846704e-04 2.143755e-01 4.468023e-01 9 137453731 137453820 90 - 2.740 2.765 0.082
ENSG00000165802 E026 532.409095 6.967911e-04 1.774040e-01 4.003093e-01 9 137454391 137454443 53 - 2.649 2.681 0.105
ENSG00000165802 E027 45.792360 1.608973e-01 1.301165e-01 3.320228e-01 9 137454444 137454537 94 - 1.780 1.538 -0.822
ENSG00000165802 E028 109.757460 1.512784e-01 2.457610e-01 4.833001e-01 9 137454538 137454977 440 - 2.100 1.941 -0.533
ENSG00000165802 E029 455.082200 3.702682e-03 9.562422e-01 9.800298e-01 9 137455239 137455307 69 - 2.603 2.602 -0.003
ENSG00000165802 E030 28.895078 5.811977e-02 2.495790e-01 4.874275e-01 9 137455629 137455634 6 - 1.532 1.380 -0.521
ENSG00000165802 E031 599.730996 8.104996e-04 5.154592e-01 7.119486e-01 9 137456411 137456486 76 - 2.732 2.721 -0.037
ENSG00000165802 E032 1317.155050 1.066197e-03 1.144725e-02 6.420735e-02 9 137457407 137457901 495 - 3.029 3.077 0.161
ENSG00000165802 E033 328.306453 4.396633e-04 4.837570e-02 1.758827e-01 9 137458488 137458549 62 - 2.428 2.477 0.164
ENSG00000165802 E034 214.210286 1.627298e-03 8.122917e-08 3.082588e-06 9 137459032 137459338 307 - 2.131 2.325 0.650