ENSG00000165097

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000297792 ENSG00000165097 HEK293_OSMI2_6hA HEK293_TMG_6hB KDM1B protein_coding protein_coding 10.44141 5.304234 17.23592 1.366732 0.659814 1.698321 0.4931405 0.05032616 1.21412302 0.03373343 0.06617971 4.342821 0.03794583 0.01066667 0.070633333 0.05996667 0.004827460 0.00482746 FALSE TRUE
ENST00000449850 ENSG00000165097 HEK293_OSMI2_6hA HEK293_TMG_6hB KDM1B protein_coding protein_coding 10.44141 5.304234 17.23592 1.366732 0.659814 1.698321 0.8938271 0.17569816 2.13496139 0.03439207 0.25296725 3.529920 0.07823750 0.03483333 0.124000000 0.08916667 0.006494861 0.00482746 FALSE TRUE
ENST00000546309 ENSG00000165097 HEK293_OSMI2_6hA HEK293_TMG_6hB KDM1B protein_coding protein_coding 10.44141 5.304234 17.23592 1.366732 0.659814 1.698321 0.2993390 0.27128997 0.02320992 0.27128997 0.02320992 -3.082372 0.05656250 0.03920000 0.001333333 -0.03786667 0.842531010 0.00482746 FALSE TRUE
ENST00000650836 ENSG00000165097 HEK293_OSMI2_6hA HEK293_TMG_6hB KDM1B protein_coding protein_coding 10.44141 5.304234 17.23592 1.366732 0.659814 1.698321 5.5775935 3.11516608 8.07859204 0.85933194 1.73543106 1.371956 0.44057917 0.58406667 0.463400000 -0.12066667 0.755390598 0.00482746 FALSE TRUE
MSTRG.27699.2 ENSG00000165097 HEK293_OSMI2_6hA HEK293_TMG_6hB KDM1B protein_coding   10.44141 5.304234 17.23592 1.366732 0.659814 1.698321 1.1680794 0.35509262 1.16254746 0.35509262 0.33665800 1.683312 0.08812917 0.05540000 0.069033333 0.01363333 0.652764322 0.00482746 FALSE TRUE
MSTRG.27699.5 ENSG00000165097 HEK293_OSMI2_6hA HEK293_TMG_6hB KDM1B protein_coding   10.44141 5.304234 17.23592 1.366732 0.659814 1.698321 1.0382375 0.96997612 3.59038526 0.64946790 0.27016780 1.877333 0.13320417 0.19723333 0.208100000 0.01086667 0.939462937 0.00482746 FALSE TRUE
MSTRG.27699.7 ENSG00000165097 HEK293_OSMI2_6hA HEK293_TMG_6hB KDM1B protein_coding   10.44141 5.304234 17.23592 1.366732 0.659814 1.698321 0.8168206 0.16260237 0.89423050 0.16260237 0.89423050 2.389238 0.13805000 0.02536667 0.055700000 0.03033333 0.934145579 0.00482746 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_6hB HEK293_OSMI2_6hA log2fold_HEK293_OSMI2_6hA_HEK293_TMG_6hB
ENSG00000165097 E001 0.3228314 0.4407797241 0.91568831   6 18155329 18155404 76 + 0.139 0.000 -10.439
ENSG00000165097 E002 0.3228314 0.4407797241 0.91568831   6 18155405 18155413 9 + 0.139 0.000 -10.391
ENSG00000165097 E003 0.3228314 0.4407797241 0.91568831   6 18155414 18155421 8 + 0.139 0.000 -10.391
ENSG00000165097 E004 0.6564337 0.0524029152 0.31867600   6 18155422 18155443 22 + 0.138 0.325 1.569
ENSG00000165097 E005 0.4950181 0.0217681645 0.14214874   6 18155444 18155451 8 + 0.075 0.325 2.570
ENSG00000165097 E006 13.7641061 0.0049075024 0.05443548 0.19010048 6 18155452 18155571 120 + 1.053 1.260 0.738
ENSG00000165097 E007 21.7565279 0.0017464595 0.27577384 0.51586714 6 18155883 18155926 44 + 1.274 1.376 0.357
ENSG00000165097 E008 1.0997382 0.0337702515 0.89605066   6 18156278 18156377 100 + 0.287 0.324 0.237
ENSG00000165097 E009 59.7236614 0.0177515609 0.74470516 0.86351079 6 18159883 18159982 100 + 1.733 1.708 -0.085
ENSG00000165097 E010 87.0356351 0.0012976669 0.41515734 0.63990910 6 18161327 18161454 128 + 1.896 1.874 -0.075
ENSG00000165097 E011 66.5790196 0.0074254795 0.19129033 0.41849273 6 18162835 18162924 90 + 1.793 1.723 -0.237
ENSG00000165097 E012 79.6990320 0.0062688316 0.64944120 0.80309071 6 18166267 18166378 112 + 1.854 1.841 -0.043
ENSG00000165097 E013 87.1946505 0.0024533242 0.87320805 0.93773608 6 18171363 18171479 117 + 1.885 1.893 0.027
ENSG00000165097 E014 41.4467479 0.0135275270 0.62369306 0.78639987 6 18185772 18185810 39 + 1.577 1.549 -0.095
ENSG00000165097 E015 64.5473505 0.0012335555 0.39023179 0.62061580 6 18187792 18188002 211 + 1.748 1.808 0.201
ENSG00000165097 E016 78.6683496 0.0032117149 0.84275325 0.92099366 6 18191197 18191381 185 + 1.848 1.855 0.025
ENSG00000165097 E017 127.7875101 0.0005883994 0.10254193 0.28630582 6 18197057 18197233 177 + 2.064 2.020 -0.145
ENSG00000165097 E018 73.7367414 0.0041412219 0.38773053 0.61869333 6 18197587 18197661 75 + 1.822 1.789 -0.111
ENSG00000165097 E019 99.1907403 0.0005181366 0.47912567 0.68650689 6 18200439 18200576 138 + 1.945 1.932 -0.043
ENSG00000165097 E020 106.9046563 0.0004454202 0.41344356 0.63864837 6 18201486 18201657 172 + 1.980 1.964 -0.052
ENSG00000165097 E021 92.2115347 0.0005652436 0.18311634 0.40798413 6 18205537 18205664 128 + 1.896 1.967 0.238
ENSG00000165097 E022 90.1204149 0.0006237266 0.68272834 0.82444385 6 18207398 18207529 132 + 1.896 1.929 0.111
ENSG00000165097 E023 3.6646700 0.0068673319 0.13863387 0.34543868 6 18208129 18208131 3 + 0.676 0.426 -1.166
ENSG00000165097 E024 65.8600749 0.0006987844 0.01250416 0.06844463 6 18208132 18208206 75 + 1.793 1.679 -0.386
ENSG00000165097 E025 4.1741200 0.2686078600 0.05281168 0.18628234 6 18211495 18212487 993 + 0.481 0.974 2.058
ENSG00000165097 E026 83.5137250 0.0005700576 0.16299042 0.38120564 6 18212488 18212604 117 + 1.881 1.834 -0.159
ENSG00000165097 E027 78.3978669 0.0012280657 0.42426519 0.64678570 6 18213656 18213781 126 + 1.850 1.827 -0.078
ENSG00000165097 E028 76.0068367 0.0005741386 0.86797280 0.93484612 6 18215007 18215129 123 + 1.829 1.837 0.029
ENSG00000165097 E029 100.6814280 0.0004577650 0.26649961 0.50599559 6 18217733 18217880 148 + 1.959 1.932 -0.093
ENSG00000165097 E030 51.5703291 0.0017561987 0.54102247 0.72976433 6 18217881 18217885 5 + 1.670 1.652 -0.061
ENSG00000165097 E031 488.0620713 0.0071393411 0.04825881 0.17561235 6 18221909 18223854 1946 + 2.605 2.697 0.306