ENSG00000164924

1 Isoform Switch

Summary Plot
Results

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

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isoform_id
gene_id
condition_1
condition_2
gene_name
gene_biotype
iso_biotype
gene_overall_mean
gene_value_1
gene_value_2
gene_stderr_1
gene_stderr_2
gene_log2_fold_change
iso_overall_mean
iso_value_1
iso_value_2
iso_stderr_1
iso_stderr_2
iso_log2_fold_change
IF_overall
IF1
IF2
dIF
isoform_switch_q_value
gene_switch_q_value
PTC
codingPotential
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isoform_id	gene_id	condition_1	condition_2	gene_name	gene_biotype	iso_biotype	gene_overall_mean	gene_value_1	gene_value_2	gene_stderr_1	gene_stderr_2	gene_log2_fold_change	iso_overall_mean	iso_value_1	iso_value_2	iso_stderr_1	iso_stderr_2	iso_log2_fold_change	IF_overall	IF1	IF2	dIF	isoform_switch_q_value	gene_switch_q_value	PTC	codingPotential

ENST00000353245	ENSG00000164924	HEK293_OSMI2_6hA	HEK293_TMG_6hB	YWHAZ	protein_coding	protein_coding	359.739	183.5154	500.5207	38.50599	23.28649	1.447479	146.02382	94.7261045	180.32600	24.4042156	10.0040267	0.9287012	0.44785833	0.50533333	0.36016667	-0.145166667	0.08570824	0.02593479	FALSE	TRUE
ENST00000395953	ENSG00000164924	HEK293_OSMI2_6hA	HEK293_TMG_6hB	YWHAZ	protein_coding	protein_coding	359.739	183.5154	500.5207	38.50599	23.28649	1.447479	19.10219	0.3371987	31.67201	0.2329523	9.5284817	6.5117583	0.03722083	0.00280000	0.06176667	0.058966667	0.02593479	0.02593479	FALSE	TRUE
ENST00000457309	ENSG00000164924	HEK293_OSMI2_6hA	HEK293_TMG_6hB	YWHAZ	protein_coding	protein_coding	359.739	183.5154	500.5207	38.50599	23.28649	1.447479	57.14770	26.8824503	71.20504	6.3751810	0.2546072	1.4049807	0.17033750	0.14413333	0.14293333	-0.001200000	1.00000000	0.02593479	FALSE	TRUE
ENST00000522542	ENSG00000164924	HEK293_OSMI2_6hA	HEK293_TMG_6hB	YWHAZ	protein_coding	protein_coding	359.739	183.5154	500.5207	38.50599	23.28649	1.447479	47.03990	15.8480971	94.69234	3.6977205	5.0683510	2.5781805	0.10352500	0.09373333	0.18923333	0.095500000	0.22695721	0.02593479	FALSE	TRUE
ENST00000523131	ENSG00000164924	HEK293_OSMI2_6hA	HEK293_TMG_6hB	YWHAZ	protein_coding	protein_coding	359.739	183.5154	500.5207	38.50599	23.28649	1.447479	63.40109	33.0994300	85.70643	6.8660877	1.4010685	1.3723295	0.17055417	0.18070000	0.17173333	-0.008966667	0.91144912	0.02593479		FALSE

Note:
- The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

All exons whithin this gene region are shown and numbering below.

All isoforms whithin this gene region are shown below.

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featureID
exonBaseMean
dispersion
pvalue
padj
seqnames
start
end
width
strand
HEK293_TMG_6hB
HEK293_OSMI2_6hA
log2fold_HEK293_OSMI2_6hA_HEK293_TMG_6hB
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groupID	featureID	exonBaseMean	dispersion	pvalue	padj	seqnames	start	end	width	strand	HEK293_TMG_6hB	HEK293_OSMI2_6hA	log2fold_HEK293_OSMI2_6hA_HEK293_TMG_6hB

ENSG00000164924	E001	0.7381610	1.756571e-02	2.074348e-01		8	100916523	100916524	2	-	0.157	0.385	1.707
ENSG00000164924	E002	89.7932394	5.415666e-04	1.200797e-05	2.456223e-04	8	100916525	100918578	2054	-	1.856	2.042	0.623
ENSG00000164924	E003	196.8655498	4.316799e-04	1.619294e-01	3.796154e-01	8	100918579	100918682	104	-	2.245	2.298	0.178
ENSG00000164924	E004	183.7595404	2.974313e-04	1.674663e-01	3.872129e-01	8	100918683	100918685	3	-	2.216	2.268	0.176
ENSG00000164924	E005	2237.3245109	7.103544e-05	1.460461e-18	3.589288e-16	8	100918686	100919061	376	-	3.289	3.377	0.294
ENSG00000164924	E006	1801.0287445	6.553312e-04	4.625301e-14	6.146185e-12	8	100919062	100919229	168	-	3.179	3.307	0.425
ENSG00000164924	E007	3183.6239934	4.236096e-03	1.264634e-04	1.816799e-03	8	100919230	100919828	599	-	3.421	3.565	0.476
ENSG00000164924	E008	5409.7013591	1.647432e-04	2.292959e-06	5.881243e-05	8	100919829	100920525	697	-	3.686	3.735	0.162
ENSG00000164924	E009	1412.2612601	1.711103e-04	8.411165e-01	9.200882e-01	8	100920526	100920586	61	-	3.115	3.127	0.039
ENSG00000164924	E010	829.7380692	2.985834e-04	1.092942e-01	2.979483e-01	8	100920587	100920589	3	-	2.892	2.881	-0.037
ENSG00000164924	E011	1169.0021407	1.222427e-04	4.136547e-04	4.864489e-03	8	100920590	100920602	13	-	3.046	3.016	-0.098
ENSG00000164924	E012	1218.6644601	8.613588e-05	8.578835e-01	9.292652e-01	8	100920603	100920629	27	-	3.051	3.062	0.037
ENSG00000164924	E013	940.1550322	4.035905e-04	9.108108e-01	9.575334e-01	8	100920630	100920641	12	-	2.938	2.949	0.038
ENSG00000164924	E014	1593.7953405	8.789747e-05	1.798925e-02	8.899409e-02	8	100920642	100920715	74	-	3.175	3.164	-0.037
ENSG00000164924	E015	1440.9407992	1.099132e-04	3.861908e-05	6.690205e-04	8	100920716	100920752	37	-	3.139	3.106	-0.108
ENSG00000164924	E016	21.8539130	1.089400e-01	3.094172e-01	5.499221e-01	8	100922438	100923954	1517	-	1.374	1.211	-0.573
ENSG00000164924	E017	1322.8216142	1.560587e-04	2.373293e-11	1.913769e-09	8	100923955	100923984	30	-	3.112	3.045	-0.224
ENSG00000164924	E018	1058.1048343	8.534859e-05	4.542965e-12	4.174783e-10	8	100923985	100923986	2	-	3.017	2.943	-0.244
ENSG00000164924	E019	1657.2020073	9.076390e-05	2.652106e-09	1.416762e-07	8	100923987	100924050	64	-	3.204	3.156	-0.160
ENSG00000164924	E020	9.7022517	4.152630e-03	2.782570e-01	5.183795e-01	8	100924051	100924134	84	-	1.026	0.911	-0.429
ENSG00000164924	E021	2431.0359913	6.476052e-04	3.358371e-04	4.097188e-03	8	100924135	100924298	164	-	3.368	3.329	-0.128
ENSG00000164924	E022	3.3063809	2.697089e-02	1.685972e-02	8.493547e-02	8	100924299	100924322	24	-	0.439	0.828	1.714
ENSG00000164924	E023	1038.9413624	8.131394e-04	3.834599e-04	4.574341e-03	8	100924916	100924921	6	-	3.003	2.950	-0.177
ENSG00000164924	E024	1910.2907697	7.247182e-04	2.684129e-04	3.410856e-03	8	100924922	100925039	118	-	3.265	3.221	-0.146
ENSG00000164924	E025	0.1308682	3.264919e-02	2.287369e-01		8	100932029	100932093	65	-	0.000	0.169	9.819
ENSG00000164924	E026	0.4043710	6.622161e-02	2.418765e-01		8	100934857	100935055	199	-	0.086	0.289	2.115
ENSG00000164924	E027	0.3503582	4.830521e-02	5.798630e-01		8	100948077	100948162	86	-	0.086	0.169	1.124
ENSG00000164924	E028	989.8300358	4.986493e-04	5.973421e-03	3.959965e-02	8	100948596	100948613	18	-	2.976	2.945	-0.103
ENSG00000164924	E029	1394.8218350	7.575324e-05	4.700784e-07	1.467466e-05	8	100948614	100948662	49	-	3.127	3.086	-0.137
ENSG00000164924	E030	1460.9460528	9.241829e-05	7.361466e-05	1.158401e-03	8	100948663	100948732	70	-	3.144	3.114	-0.100
ENSG00000164924	E031	736.8085352	1.241914e-04	1.050634e-02	6.028397e-02	8	100948733	100948734	2	-	2.845	2.820	-0.084
ENSG00000164924	E032	1540.7057402	1.517705e-04	2.076430e-02	9.855656e-02	8	100948735	100948900	166	-	3.162	3.149	-0.042
ENSG00000164924	E033	10.0031091	6.577041e-02	8.951436e-01	9.492933e-01	8	100950406	100950557	152	-	1.025	1.014	-0.042
ENSG00000164924	E034	2.6132420	1.260515e-01	2.290397e-01	4.640165e-01	8	100950909	100951185	277	-	0.440	0.684	1.130
ENSG00000164924	E035	0.2735028	2.617790e-02	5.824938e-01		8	100951186	100951234	49	-	0.086	0.169	1.123
ENSG00000164924	E036	3.5661074	3.031626e-01	6.744387e-01	8.191735e-01	8	100951235	100951449	215	-	0.590	0.720	0.554
ENSG00000164924	E037	1.9700525	1.092764e-02	4.952926e-01	6.976630e-01	8	100951456	100951595	140	-	0.403	0.529	0.637
ENSG00000164924	E038	696.0541367	6.722993e-04	7.668679e-01	8.767457e-01	8	100951929	100951955	27	-	2.810	2.818	0.025
ENSG00000164924	E039	606.5738415	1.550987e-03	8.057557e-01	8.995553e-01	8	100951956	100952125	170	-	2.747	2.767	0.067
ENSG00000164924	E040	33.5811074	1.072277e-03	4.334242e-02	1.634477e-01	8	100952126	100952308	183	-	1.459	1.598	0.476
ENSG00000164924	E041	18.9993232	1.898312e-03	3.094698e-02	1.301997e-01	8	100952309	100952472	164	-	1.200	1.387	0.653
ENSG00000164924	E042	6.2724046	2.210469e-02	3.567498e-01	5.931324e-01	8	100952473	100952619	147	-	0.780	0.914	0.519
ENSG00000164924	E043	89.4548775	2.140899e-03	2.403681e-02	1.091912e-01	8	100952850	100953057	208	-	1.953	1.862	-0.305
ENSG00000164924	E044	52.8735975	9.193043e-01	5.062514e-01	7.051165e-01	8	100953269	100953388	120	-	1.662	1.776	0.385

Isoforom Switch Analysis

WANG Ziyi

Date: 19 5月 2022

ENSG00000164924

1 Isoform Switch

TableFilter v0.7.3

2 Differential Exon Usage

TableFilter v0.7.3