ENSG00000164329

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000423041 ENSG00000164329 HEK293_OSMI2_6hA HEK293_TMG_6hB TENT2 protein_coding protein_coding 12.32873 2.716881 20.27192 0.1593138 0.9370365 2.89487 1.3774022 0.2804636 2.7369348 0.1447789 0.4553380 3.2413933 0.13319583 0.1099333 0.13363333 0.02370000 8.748474e-01 7.707714e-08 FALSE TRUE
ENST00000453514 ENSG00000164329 HEK293_OSMI2_6hA HEK293_TMG_6hB TENT2 protein_coding protein_coding 12.32873 2.716881 20.27192 0.1593138 0.9370365 2.89487 3.7447908 1.2808665 5.9745664 0.3205812 0.4757130 2.2129069 0.34521667 0.4683667 0.29770000 -0.17066667 6.170334e-01 7.707714e-08 FALSE TRUE
ENST00000502269 ENSG00000164329 HEK293_OSMI2_6hA HEK293_TMG_6hB TENT2 protein_coding processed_transcript 12.32873 2.716881 20.27192 0.1593138 0.9370365 2.89487 1.2485670 0.1035494 2.7962537 0.1035494 0.5259660 4.6272539 0.06062083 0.0396000 0.13656667 0.09696667 3.747897e-01 7.707714e-08   FALSE
ENST00000503620 ENSG00000164329 HEK293_OSMI2_6hA HEK293_TMG_6hB TENT2 protein_coding processed_transcript 12.32873 2.716881 20.27192 0.1593138 0.9370365 2.89487 0.9564579 0.3436771 1.0987255 0.2194465 0.2804491 1.6483975 0.05860000 0.1330000 0.05373333 -0.07926667 9.457614e-01 7.707714e-08 FALSE FALSE
ENST00000509227 ENSG00000164329 HEK293_OSMI2_6hA HEK293_TMG_6hB TENT2 protein_coding retained_intron 12.32873 2.716881 20.27192 0.1593138 0.9370365 2.89487 0.6932480 0.2974341 1.1939914 0.1089723 0.1420964 1.9694758 0.06345833 0.1059333 0.05853333 -0.04740000 4.932176e-01 7.707714e-08   FALSE
ENST00000514095 ENSG00000164329 HEK293_OSMI2_6hA HEK293_TMG_6hB TENT2 protein_coding processed_transcript 12.32873 2.716881 20.27192 0.1593138 0.9370365 2.89487 2.3114141 0.0000000 3.5006103 0.0000000 0.4906282 8.4555780 0.10442917 0.0000000 0.17286667 0.17286667 7.707714e-08 7.707714e-08   FALSE
ENST00000515807 ENSG00000164329 HEK293_OSMI2_6hA HEK293_TMG_6hB TENT2 protein_coding processed_transcript 12.32873 2.716881 20.27192 0.1593138 0.9370365 2.89487 0.6595636 0.0000000 1.4781809 0.0000000 0.4903847 7.2174061 0.03195833 0.0000000 0.07266667 0.07266667 6.599006e-03 7.707714e-08 FALSE FALSE
MSTRG.26473.8 ENSG00000164329 HEK293_OSMI2_6hA HEK293_TMG_6hB TENT2 protein_coding   12.32873 2.716881 20.27192 0.1593138 0.9370365 2.89487 0.3083355 0.3052279 0.2784857 0.2343552 0.2784857 -0.1278954 0.07098333 0.1041667 0.01410000 -0.09006667 5.716419e-01 7.707714e-08 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_6hB HEK293_OSMI2_6hA log2fold_HEK293_OSMI2_6hA_HEK293_TMG_6hB
ENSG00000164329 E001 0.0000000       5 79612120 79612174 55 +      
ENSG00000164329 E002 0.0000000       5 79612433 79612434 2 +      
ENSG00000164329 E003 0.1426347 0.0328647841 1.000000000   5 79612435 79612440 6 + 0.062 0.000 -8.139
ENSG00000164329 E004 18.8539927 0.0019824741 0.925215087 0.96484330 5 79612441 79612484 44 + 1.201 1.202 0.005
ENSG00000164329 E005 22.2352464 0.0018011924 0.466795246 0.67786446 5 79612485 79612502 18 + 1.277 1.220 -0.202
ENSG00000164329 E006 23.9618662 0.0018400291 0.472647594 0.68195779 5 79612503 79612519 17 + 1.308 1.254 -0.189
ENSG00000164329 E007 24.7914821 0.0025856137 0.491836302 0.69521996 5 79612520 79612529 10 + 1.321 1.270 -0.178
ENSG00000164329 E008 31.5888908 0.0034678669 0.346901575 0.58447059 5 79612530 79612572 43 + 1.423 1.356 -0.234
ENSG00000164329 E009 26.0845885 0.0074599277 0.706952075 0.83988260 5 79612573 79612574 2 + 1.337 1.314 -0.082
ENSG00000164329 E010 41.7647030 0.0025894524 0.375039956 0.60820884 5 79612575 79612617 43 + 1.534 1.479 -0.186
ENSG00000164329 E011 59.9415261 0.0007156329 0.043661966 0.16427335 5 79612618 79612691 74 + 1.696 1.584 -0.381
ENSG00000164329 E012 48.5795313 0.0008833537 0.046528265 0.17136719 5 79612692 79612735 44 + 1.613 1.489 -0.422
ENSG00000164329 E013 38.4068900 0.0012384914 0.012546473 0.06862314 5 79612736 79612769 34 + 1.525 1.343 -0.628
ENSG00000164329 E014 55.3508171 0.0007744113 0.097383896 0.27719064 5 79612770 79613010 241 + 1.661 1.568 -0.316
ENSG00000164329 E015 55.3907409 0.0008896614 0.012280575 0.06756431 5 79613011 79613075 65 + 1.668 1.517 -0.514
ENSG00000164329 E016 1.6294355 0.0138422153 0.918118647 0.96126796 5 79613935 79614083 149 + 0.348 0.373 0.147
ENSG00000164329 E017 0.9694175 0.0481598287 0.401355304   5 79615075 79615163 89 + 0.208 0.373 1.152
ENSG00000164329 E018 2.6855560 0.1319203258 0.554618498 0.73953616 5 79617530 79617599 70 + 0.456 0.576 0.573
ENSG00000164329 E019 73.0359688 0.0007710161 0.755283890 0.86984393 5 79619612 79619785 174 + 1.758 1.783 0.086
ENSG00000164329 E020 56.1094963 0.0006844141 0.103580758 0.28816184 5 79619994 79620083 90 + 1.631 1.732 0.344
ENSG00000164329 E021 0.5233527 0.0213492393 0.522707295   5 79620567 79620617 51 + 0.116 0.225 1.149
ENSG00000164329 E022 107.1692116 0.0036383647 0.763312339 0.87464739 5 79623252 79623489 238 + 1.930 1.922 -0.029
ENSG00000164329 E023 0.4820342 0.0213032556 0.701537734   5 79623490 79623648 159 + 0.164 0.000 -9.716
ENSG00000164329 E024 70.8779984 0.0039874999 0.749314335 0.86635000 5 79640851 79640965 115 + 1.753 1.746 -0.025
ENSG00000164329 E025 61.2926159 0.0012854882 0.841298734 0.92018365 5 79641105 79641196 92 + 1.686 1.709 0.076
ENSG00000164329 E026 22.4040322 0.0015160123 0.882004394 0.94236176 5 79642832 79642843 12 + 1.263 1.286 0.081
ENSG00000164329 E027 63.2934155 0.0006704944 0.929815782 0.96689279 5 79642844 79642910 67 + 1.704 1.709 0.019
ENSG00000164329 E028 8.7148061 0.0039899611 0.384926294 0.61647087 5 79644646 79645122 477 + 0.872 0.992 0.452
ENSG00000164329 E029 67.5903599 0.0007179831 0.266579336 0.50607853 5 79645123 79645192 70 + 1.742 1.692 -0.172
ENSG00000164329 E030 62.4580968 0.0027601490 0.151011165 0.36374063 5 79648617 79648693 77 + 1.713 1.634 -0.269
ENSG00000164329 E031 0.3040503 0.0274424043 1.000000000   5 79648705 79648861 157 + 0.116 0.000 -9.129
ENSG00000164329 E032 0.8380019 0.0230580422 0.342899245   5 79648862 79649061 200 + 0.247 0.000 -10.455
ENSG00000164329 E033 80.5035565 0.0005180465 0.907364137 0.95578871 5 79649062 79649190 129 + 1.804 1.820 0.054
ENSG00000164329 E034 1.3709419 0.0591269359 0.057401628   5 79656881 79656957 77 + 0.208 0.572 2.151
ENSG00000164329 E035 42.4973206 0.0009470361 0.006232382 0.04087283 5 79656958 79657001 44 + 1.499 1.679 0.616
ENSG00000164329 E036 0.8878102 0.0789247662 0.018287417   5 79668721 79668891 171 + 0.116 0.566 3.126
ENSG00000164329 E037 76.8051449 0.0005286125 0.247471309 0.48525335 5 79668892 79669028 137 + 1.775 1.842 0.226
ENSG00000164329 E038 70.1364526 0.0005767893 0.606997338 0.77487158 5 79679579 79679670 92 + 1.741 1.778 0.125
ENSG00000164329 E039 0.9335208 0.0158152359 0.947501713   5 79681652 79681981 330 + 0.247 0.225 -0.177
ENSG00000164329 E040 61.8870391 0.0008105012 0.984480668 0.99409861 5 79681982 79682061 80 + 1.693 1.704 0.037
ENSG00000164329 E041 253.9016880 0.0059566261 0.007101348 0.04508476 5 79685199 79688246 3048 + 2.276 2.391 0.382