ENSG00000164292

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000379982 ENSG00000164292 HEK293_OSMI2_6hA HEK293_TMG_6hB RHOBTB3 protein_coding protein_coding 7.525973 3.180587 9.966586 0.7078531 0.4067793 1.644724 5.1302118 1.8739844 8.288108 0.4253585 0.25332364 2.138996 0.60986250 0.5880667 0.8322667 0.2442000 2.165080e-05 1.198266e-17 FALSE TRUE
ENST00000503737 ENSG00000164292 HEK293_OSMI2_6hA HEK293_TMG_6hB RHOBTB3 protein_coding protein_coding 7.525973 3.180587 9.966586 0.7078531 0.4067793 1.644724 0.6547553 0.7908612 0.000000 0.1208189 0.00000000 -6.323480 0.19439583 0.2600333 0.0000000 -0.2600333 1.198266e-17 1.198266e-17 FALSE FALSE
MSTRG.26619.5 ENSG00000164292 HEK293_OSMI2_6hA HEK293_TMG_6hB RHOBTB3 protein_coding   7.525973 3.180587 9.966586 0.7078531 0.4067793 1.644724 0.5168700 0.0000000 0.558624 0.0000000 0.03466658 5.829403 0.04703333 0.0000000 0.0560000 0.0560000 2.467067e-04 1.198266e-17 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_6hB HEK293_OSMI2_6hA log2fold_HEK293_OSMI2_6hA_HEK293_TMG_6hB
ENSG00000164292 E001 0.0000000       5 95713522 95713590 69 +      
ENSG00000164292 E002 0.0000000       5 95713591 95713711 121 +      
ENSG00000164292 E003 0.0000000       5 95717535 95717632 98 +      
ENSG00000164292 E004 0.0000000       5 95717633 95717765 133 +      
ENSG00000164292 E005 0.0000000       5 95730872 95730896 25 +      
ENSG00000164292 E006 4.2125855 0.0431252877 0.9982653693 1.000000000 5 95731146 95731335 190 + 0.646 0.668 0.090
ENSG00000164292 E007 2.5202174 0.2781126957 0.8152265544 0.905357056 5 95731336 95731343 8 + 0.481 0.535 0.257
ENSG00000164292 E008 14.9817746 0.0600300000 0.4701991468 0.680218557 5 95731344 95731684 341 + 1.107 1.232 0.446
ENSG00000164292 E009 0.3393995 0.0274424043 0.8991348652   5 95731725 95731858 134 + 0.129 0.000 -10.962
ENSG00000164292 E010 18.9913026 0.1513599740 0.9563049786 0.980051807 5 95731859 95731955 97 + 1.234 1.223 -0.038
ENSG00000164292 E011 26.1696129 0.7754764500 0.6760624166 0.820227265 5 95731956 95732055 100 + 1.363 1.352 -0.037
ENSG00000164292 E012 19.9203638 0.6580771795 0.4773998639 0.685303645 5 95732056 95732084 29 + 1.221 1.331 0.386
ENSG00000164292 E013 2.0776978 0.0536933793 0.0244217658 0.110417123 5 95732085 95732751 667 + 0.307 0.720 2.051
ENSG00000164292 E014 25.6306458 0.0787290813 0.9008859164 0.952323386 5 95736889 95736938 50 + 1.361 1.337 -0.084
ENSG00000164292 E015 41.2706112 0.0131806760 0.2010078349 0.430985222 5 95736939 95737075 137 + 1.574 1.484 -0.311
ENSG00000164292 E016 19.3290123 0.0017092958 0.1138486908 0.305528140 5 95748333 95748335 3 + 1.264 1.136 -0.454
ENSG00000164292 E017 48.1672722 0.0008006415 0.0685722735 0.221871301 5 95748336 95748487 152 + 1.637 1.550 -0.298
ENSG00000164292 E018 45.1986007 0.0008244165 0.0253850530 0.113392758 5 95752239 95752350 112 + 1.614 1.494 -0.408
ENSG00000164292 E019 85.7815102 0.0016808236 0.0068660907 0.044017370 5 95755396 95755761 366 + 1.884 1.775 -0.366
ENSG00000164292 E020 1.5310724 0.0160835047 0.0738498334 0.232480634 5 95755762 95756093 332 + 0.270 0.604 1.808
ENSG00000164292 E021 46.3336333 0.0018404121 0.0081906710 0.050209881 5 95763508 95763620 113 + 1.629 1.477 -0.518
ENSG00000164292 E022 0.1308682 0.0326491905 0.1329604853   5 95767755 95767890 136 + 0.000 0.205 11.597
ENSG00000164292 E023 31.0993244 0.0037661765 0.8341461936 0.916110870 5 95768046 95768139 94 + 1.426 1.432 0.019
ENSG00000164292 E024 20.4270468 0.0020818390 0.6564952360 0.807634123 5 95768140 95768166 27 + 1.256 1.239 -0.062
ENSG00000164292 E025 0.3807181 0.0337722466 0.3770805150   5 95780007 95780251 245 + 0.069 0.206 1.815
ENSG00000164292 E026 22.6571212 0.0121887250 0.6362064068 0.794441626 5 95780252 95780320 69 + 1.281 1.347 0.230
ENSG00000164292 E027 31.8994531 0.0017323850 0.3932242692 0.622945625 5 95780321 95780425 105 + 1.420 1.503 0.286
ENSG00000164292 E028 0.0000000       5 95783582 95783796 215 +      
ENSG00000164292 E029 23.3897311 0.0014887141 0.3415664157 0.579431841 5 95783797 95783833 37 + 1.292 1.391 0.343
ENSG00000164292 E030 39.2597175 0.0009411316 0.8886623119 0.945991072 5 95783834 95783963 130 + 1.528 1.542 0.049
ENSG00000164292 E031 32.5799346 0.0010664874 0.9777421876 0.990672211 5 95788762 95788814 53 + 1.448 1.469 0.072
ENSG00000164292 E032 21.7370039 0.0016641255 0.1704850363 0.391088482 5 95788815 95788820 6 + 1.307 1.207 -0.352
ENSG00000164292 E033 30.3080625 0.0014718339 0.1789463955 0.402570127 5 95788821 95788858 38 + 1.437 1.357 -0.276
ENSG00000164292 E034 4.5464092 0.0159405201 0.0673263612 0.219075822 5 95788859 95789383 525 + 0.594 0.885 1.190
ENSG00000164292 E035 0.1426347 0.0328740397 1.0000000000   5 95793039 95793058 20 + 0.069 0.000 -9.953
ENSG00000164292 E036 36.3405326 0.0015627640 0.4406623614 0.659201820 5 95793059 95793170 112 + 1.500 1.469 -0.109
ENSG00000164292 E037 127.4169635 0.0051264083 0.5028803107 0.702765790 5 95793171 95794018 848 + 2.033 2.025 -0.028
ENSG00000164292 E038 333.9245496 0.0043193930 0.0002055211 0.002735577 5 95794019 95796361 2343 + 2.415 2.544 0.430
ENSG00000164292 E039 1.2179823 0.0423682893 0.3871587269   5 95823837 95824383 547 + 0.269 0.448 1.071