ENSG00000164163

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000296577 ENSG00000164163 HEK293_OSMI2_6hA HEK293_TMG_6hB ABCE1 protein_coding protein_coding 69.6225 20.1104 129.0567 7.045505 6.951033 2.681386 39.6190782 15.4528912 69.03287297 6.2389676 1.12659360 2.158682 0.63395833 0.71380000 0.5372333 -0.17656667 3.804817e-01 2.42458e-13 FALSE TRUE
ENST00000502586 ENSG00000164163 HEK293_OSMI2_6hA HEK293_TMG_6hB ABCE1 protein_coding protein_coding 69.6225 20.1104 129.0567 7.045505 6.951033 2.681386 15.3782064 0.2499831 30.13776820 0.2499831 2.37066583 6.857490 0.13042083 0.03683333 0.2335667 0.19673333 1.451595e-01 2.42458e-13 FALSE FALSE
ENST00000502803 ENSG00000164163 HEK293_OSMI2_6hA HEK293_TMG_6hB ABCE1 protein_coding processed_transcript 69.6225 20.1104 129.0567 7.045505 6.951033 2.681386 5.9386720 0.0000000 14.80375299 0.0000000 3.14016262 10.532721 0.04798333 0.00000000 0.1130667 0.11306667 2.424580e-13 2.42458e-13 FALSE FALSE
MSTRG.25580.5 ENSG00000164163 HEK293_OSMI2_6hA HEK293_TMG_6hB ABCE1 protein_coding   69.6225 20.1104 129.0567 7.045505 6.951033 2.681386 0.7172433 1.3998736 0.06852606 0.7166716 0.06852606 -4.166250 0.03967083 0.05246667 0.0005000 -0.05196667 1.915144e-01 2.42458e-13 FALSE TRUE
MSTRG.25580.6 ENSG00000164163 HEK293_OSMI2_6hA HEK293_TMG_6hB ABCE1 protein_coding   69.6225 20.1104 129.0567 7.045505 6.951033 2.681386 2.6965389 1.9760040 6.22187222 0.6910964 1.90639522 1.649797 0.04653333 0.12140000 0.0474000 -0.07400000 4.687157e-01 2.42458e-13 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_6hB HEK293_OSMI2_6hA log2fold_HEK293_OSMI2_6hA_HEK293_TMG_6hB
ENSG00000164163 E001 0.0000000       4 145098276 145098276 1 +      
ENSG00000164163 E002 0.0000000       4 145098277 145098278 2 +      
ENSG00000164163 E003 1.4704050 0.1622534530 0.0376470741 0.148716889 4 145098279 145098287 9 + 0.214 0.632 2.366
ENSG00000164163 E004 24.3417766 0.7260650956 0.4295830142 0.650710232 4 145098288 145098310 23 + 1.294 1.385 0.318
ENSG00000164163 E005 33.1376564 0.8102411481 0.5135861358 0.710672749 4 145098311 145098313 3 + 1.437 1.465 0.098
ENSG00000164163 E006 63.9592358 0.9536348847 0.4661563972 0.677369480 4 145098314 145098330 17 + 1.699 1.798 0.336
ENSG00000164163 E007 228.9927089 1.6371275438 0.5905172192 0.764069506 4 145098331 145098419 89 + 2.253 2.324 0.238
ENSG00000164163 E008 135.5585224 0.5938932560 0.4536133722 0.668407801 4 145104386 145104388 3 + 2.032 2.080 0.159
ENSG00000164163 E009 404.1051354 0.0410018729 0.8391287401 0.918908170 4 145104389 145104515 127 + 2.517 2.507 -0.032
ENSG00000164163 E010 365.0382717 0.0002027542 0.0005385556 0.006024182 4 145105605 145105690 86 + 2.483 2.444 -0.132
ENSG00000164163 E011 203.4663789 0.0051850359 0.0017788231 0.015557527 4 145108015 145108026 12 + 2.240 2.138 -0.342
ENSG00000164163 E012 376.5026019 0.0062530418 0.0017063617 0.015060520 4 145108027 145108112 86 + 2.505 2.403 -0.338
ENSG00000164163 E013 471.9439244 0.0054210823 0.0023381741 0.019303027 4 145109132 145109249 118 + 2.599 2.518 -0.270
ENSG00000164163 E014 435.8863903 0.0002045016 0.0001999520 0.002675000 4 145110103 145110240 138 + 2.561 2.523 -0.125
ENSG00000164163 E015 345.7954312 0.0068709406 0.4216572095 0.644880227 4 145110375 145110444 70 + 2.451 2.445 -0.019
ENSG00000164163 E016 258.8398659 1.6657005657 0.6060807446 0.774249835 4 145110968 145111064 97 + 2.300 2.396 0.319
ENSG00000164163 E017 280.1251698 0.0425539671 0.7795999280 0.884466347 4 145112239 145112328 90 + 2.351 2.378 0.091
ENSG00000164163 E018 360.6170803 0.0002110781 0.7515853156 0.867749487 4 145117293 145117414 122 + 2.464 2.498 0.114
ENSG00000164163 E019 0.5008152 0.0582871610 0.6798570311   4 145117415 145117415 1 + 0.172 0.001 -8.578
ENSG00000164163 E020 270.6973242 0.0115444460 0.3161324478 0.556152993 4 145119932 145119967 36 + 2.345 2.327 -0.060
ENSG00000164163 E021 599.1461717 0.0049102183 0.1683396289 0.388343963 4 145119968 145120153 186 + 2.688 2.680 -0.027
ENSG00000164163 E022 8.4348388 0.0204736461 0.7481176259 0.865576446 4 145121010 145121033 24 + 0.892 0.872 -0.075
ENSG00000164163 E023 19.1606379 0.2864780834 0.6419534630 0.798102908 4 145121034 145121173 140 + 1.241 1.109 -0.469
ENSG00000164163 E024 416.3816612 0.0032008457 0.1563709650 0.371429980 4 145121174 145121233 60 + 2.532 2.520 -0.041
ENSG00000164163 E025 12.3589302 0.0125989258 0.2142965832 0.446714481 4 145121234 145121319 86 + 1.067 0.940 -0.467
ENSG00000164163 E026 7.8413040 0.0202363955 0.7710892669 0.879322405 4 145121320 145121332 13 + 0.880 0.869 -0.042
ENSG00000164163 E027 252.7208486 0.0034982789 0.1922071086 0.419665820 4 145121333 145121335 3 + 2.318 2.303 -0.051
ENSG00000164163 E028 392.5586573 0.0043438685 0.3629420452 0.598081693 4 145121336 145121391 56 + 2.505 2.501 -0.010
ENSG00000164163 E029 8.8390203 0.0294969052 0.1174327997 0.311538273 4 145121392 145121603 212 + 0.853 1.098 0.913
ENSG00000164163 E030 7.3508795 0.0682466665 0.5812682585 0.757981736 4 145121604 145121813 210 + 0.814 0.961 0.561
ENSG00000164163 E031 20.1186942 0.3232009471 0.8786756490 0.940602165 4 145121814 145122868 1055 + 1.225 1.276 0.181
ENSG00000164163 E032 5.6315296 0.2925646040 0.9924618514 0.997920879 4 145122869 145123020 152 + 0.747 0.735 -0.048
ENSG00000164163 E033 451.5691622 0.0091002654 0.9497426675 0.976941452 4 145123021 145123131 111 + 2.557 2.588 0.104
ENSG00000164163 E034 520.5930896 0.0122877519 0.7042088876 0.838263526 4 145123215 145123357 143 + 2.613 2.671 0.193
ENSG00000164163 E035 2.7994807 0.0102231080 0.0761435464 0.237034178 4 145123358 145123477 120 + 0.417 0.742 1.484
ENSG00000164163 E036 457.7803656 0.0098275667 0.4449890005 0.662144402 4 145123478 145123600 123 + 2.551 2.634 0.277
ENSG00000164163 E037 3.6578928 0.0164484594 0.6367127297 0.794828476 4 145123601 145123931 331 + 0.609 0.553 -0.252
ENSG00000164163 E038 405.1684636 0.0074682156 0.6011163600 0.770905203 4 145124990 145125101 112 + 2.500 2.578 0.259
ENSG00000164163 E039 1754.9448382 0.0051582982 0.0014208644 0.013047934 4 145127526 145129524 1999 + 3.118 3.263 0.484