ENSG00000163904

1 Isoform Switch

Summary Plot
Results

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Rows: 1-8 / 8
Columns:
Select all:
isoform_id
gene_id
condition_1
condition_2
gene_name
gene_biotype
iso_biotype
gene_overall_mean
gene_value_1
gene_value_2
gene_stderr_1
gene_stderr_2
gene_log2_fold_change
iso_overall_mean
iso_value_1
iso_value_2
iso_stderr_1
iso_stderr_2
iso_log2_fold_change
IF_overall
IF1
IF2
dIF
isoform_switch_q_value
gene_switch_q_value
PTC
codingPotential
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isoform_id	gene_id	condition_1	condition_2	gene_name	gene_biotype	iso_biotype	gene_overall_mean	gene_value_1	gene_value_2	gene_stderr_1	gene_stderr_2	gene_log2_fold_change	iso_overall_mean	iso_value_1	iso_value_2	iso_stderr_1	iso_stderr_2	iso_log2_fold_change	IF_overall	IF1	IF2	dIF	isoform_switch_q_value	gene_switch_q_value	PTC	codingPotential

ENST00000296257	ENSG00000163904	HEK293_OSMI2_6hA	HEK293_TMG_6hB	SENP2	protein_coding	protein_coding	23.50481	13.48167	38.58231	2.369641	0.3091891	1.516244	7.0621576	6.9011861	6.0211954	1.1236675	0.2055725	-0.1964893	0.40892500	0.51846667	0.156166667	-0.36230000	2.514249e-10	2.514249e-10	FALSE	TRUE
ENST00000413407	ENSG00000163904	HEK293_OSMI2_6hA	HEK293_TMG_6hB	SENP2	protein_coding	nonsense_mediated_decay	23.50481	13.48167	38.58231	2.369641	0.3091891	1.516244	0.7389892	0.9051481	0.3361489	0.9051481	0.3361489	-1.4026123	0.03002083	0.05993333	0.008833333	-0.05110000	9.662169e-01	2.514249e-10	FALSE	TRUE
ENST00000444509	ENSG00000163904	HEK293_OSMI2_6hA	HEK293_TMG_6hB	SENP2	protein_coding	protein_coding	23.50481	13.48167	38.58231	2.369641	0.3091891	1.516244	0.2927962	0.7380117	0.0000000	0.4082242	0.0000000	-6.2249890	0.02613333	0.06153333	0.000000000	-0.06153333	2.191468e-01	2.514249e-10	FALSE	FALSE
ENST00000478001	ENSG00000163904	HEK293_OSMI2_6hA	HEK293_TMG_6hB	SENP2	protein_coding	retained_intron	23.50481	13.48167	38.58231	2.369641	0.3091891	1.516244	0.2606074	0.8551325	0.2019427	0.8551325	0.2019427	-2.0292466	0.01655000	0.09703333	0.005300000	-0.09173333	9.675183e-01	2.514249e-10	FALSE	FALSE
ENST00000483005	ENSG00000163904	HEK293_OSMI2_6hA	HEK293_TMG_6hB	SENP2	protein_coding	retained_intron	23.50481	13.48167	38.58231	2.369641	0.3091891	1.516244	4.2518248	1.2799178	10.3390445	1.2799178	0.6580415	3.0041465	0.13775417	0.07746667	0.267833333	0.19036667	2.365079e-01	2.514249e-10	FALSE	FALSE
MSTRG.24214.11	ENSG00000163904	HEK293_OSMI2_6hA	HEK293_TMG_6hB	SENP2	protein_coding		23.50481	13.48167	38.58231	2.369641	0.3091891	1.516244	4.6553131	0.8959934	8.2381527	0.5064346	0.4448259	3.1864986	0.14079167	0.05600000	0.213466667	0.15746667	4.246883e-01	2.514249e-10	FALSE	FALSE
MSTRG.24214.3	ENSG00000163904	HEK293_OSMI2_6hA	HEK293_TMG_6hB	SENP2	protein_coding		23.50481	13.48167	38.58231	2.369641	0.3091891	1.516244	2.8482814	0.9789585	6.6782382	0.7542083	0.6745559	2.7576444	0.10370417	0.06013333	0.173066667	0.11293333	4.821682e-01	2.514249e-10	FALSE	TRUE
MSTRG.24214.5	ENSG00000163904	HEK293_OSMI2_6hA	HEK293_TMG_6hB	SENP2	protein_coding		23.50481	13.48167	38.58231	2.369641	0.3091891	1.516244	2.5380594	0.5693677	6.1031273	0.2888801	0.2049085	3.3993596	0.07906667	0.03590000	0.158266667	0.12236667	3.112948e-01	2.514249e-10	FALSE	TRUE

Note:
- The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

All exons whithin this gene region are shown and numbering below.

All isoforms whithin this gene region are shown below.

Rows: 1-10 / 39
Columns:
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groupID
featureID
exonBaseMean
dispersion
pvalue
padj
seqnames
start
end
width
strand
HEK293_TMG_6hB
HEK293_OSMI2_6hA
log2fold_HEK293_OSMI2_6hA_HEK293_TMG_6hB
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groupID	featureID	exonBaseMean	dispersion	pvalue	padj	seqnames	start	end	width	strand	HEK293_TMG_6hB	HEK293_OSMI2_6hA	log2fold_HEK293_OSMI2_6hA_HEK293_TMG_6hB

ENSG00000163904	E001	0.0000000				3	185582496	185582783	288	+
ENSG00000163904	E002	0.0000000				3	185582784	185582817	34	+
ENSG00000163904	E003	0.0000000				3	185582818	185582863	46	+
ENSG00000163904	E004	0.6081007	0.0221930789	1.162680e-01		3	185586241	185586258	18	+	0.292	0.000	-10.264
ENSG00000163904	E005	1.9953210	0.0105372650	8.898844e-02	2.619113e-01	3	185586259	185586294	36	+	0.561	0.271	-1.610
ENSG00000163904	E006	1.9953210	0.0105372650	8.898844e-02	2.619113e-01	3	185586295	185586297	3	+	0.561	0.271	-1.610
ENSG00000163904	E007	2.7530708	0.0897050143	1.060243e-01	2.923834e-01	3	185586298	185586310	13	+	0.662	0.357	-1.491
ENSG00000163904	E008	3.9724581	0.0764425950	5.614207e-01	7.442723e-01	3	185586311	185586321	11	+	0.725	0.642	-0.349
ENSG00000163904	E009	74.7464011	0.0054981594	2.070449e-01	4.382414e-01	3	185586322	185586514	193	+	1.881	1.841	-0.133
ENSG00000163904	E010	75.1477878	0.0094048760	3.715867e-02	1.473393e-01	3	185590114	185590169	56	+	1.904	1.798	-0.357
ENSG00000163904	E011	0.3032425	0.0274424043	9.129103e-02		3	185598394	185598411	18	+	0.000	0.271	10.928
ENSG00000163904	E012	106.9281910	0.0061478627	3.237261e-02	1.343118e-01	3	185598412	185598545	134	+	2.049	1.963	-0.288
ENSG00000163904	E013	48.7541792	0.0010475251	7.290240e-03	4.601734e-02	3	185598958	185598964	7	+	1.723	1.602	-0.411
ENSG00000163904	E014	56.9840349	0.0010757471	2.770774e-02	1.204354e-01	3	185598965	185598991	27	+	1.780	1.694	-0.290
ENSG00000163904	E015	65.8099173	0.0013665935	4.808077e-02	1.751780e-01	3	185598992	185599024	33	+	1.837	1.767	-0.234
ENSG00000163904	E016	2.1347473	0.0352865046	9.014138e-01	9.525933e-01	3	185599025	185599029	5	+	0.499	0.499	-0.004
ENSG00000163904	E017	94.3665367	0.0005492217	8.806533e-03	5.296426e-02	3	185600765	185600855	91	+	1.991	1.916	-0.254
ENSG00000163904	E018	158.9670928	0.0006079253	5.823034e-04	6.422583e-03	3	185606330	185606498	169	+	2.212	2.131	-0.270
ENSG00000163904	E019	1.7134777	0.0255115101	1.505798e-01	3.631343e-01	3	185609003	185609246	244	+	0.293	0.558	1.440
ENSG00000163904	E020	183.5127800	0.0009189285	6.751996e-07	2.020162e-05	3	185609247	185609350	104	+	2.288	2.161	-0.423
ENSG00000163904	E021	1.2247595	0.2061293666	6.458311e-01		3	185611528	185611650	123	+	0.382	0.271	-0.703
ENSG00000163904	E022	184.8116817	0.0027273185	5.721032e-05	9.358147e-04	3	185611651	185611745	95	+	2.291	2.167	-0.415
ENSG00000163904	E023	0.0000000				3	185612222	185612606	385	+
ENSG00000163904	E024	139.3724387	0.0089842414	4.902525e-02	1.772708e-01	3	185612607	185612658	52	+	2.162	2.072	-0.301
ENSG00000163904	E025	97.4353829	0.0176685612	1.756420e-01	3.979887e-01	3	185613345	185613354	10	+	2.006	1.921	-0.286
ENSG00000163904	E026	124.4137531	0.0103985646	2.276322e-01	4.625336e-01	3	185613355	185613408	54	+	2.101	2.046	-0.182
ENSG00000163904	E027	2.1811566	0.1527944597	5.079279e-01	7.063767e-01	3	185613409	185613644	236	+	0.429	0.562	0.651
ENSG00000163904	E028	1.4091377	0.0127605607	6.519593e-01	8.047646e-01	3	185614503	185614563	61	+	0.343	0.436	0.527
ENSG00000163904	E029	206.5404933	0.0067873379	8.026976e-01	8.978612e-01	3	185614564	185614740	177	+	2.290	2.319	0.095
ENSG00000163904	E030	163.3221005	0.0003372232	2.956881e-02	1.260913e-01	3	185617480	185617611	132	+	2.214	2.176	-0.127
ENSG00000163904	E031	197.9643020	0.0003345098	4.693663e-02	1.724150e-01	3	185619299	185619502	204	+	2.292	2.265	-0.089
ENSG00000163904	E032	0.4349185	0.0217681645	9.343259e-01		3	185619503	185619519	17	+	0.170	0.156	-0.150
ENSG00000163904	E033	115.7730398	0.0004318707	9.700839e-01	9.868997e-01	3	185621826	185621905	80	+	2.039	2.065	0.089
ENSG00000163904	E034	134.6974770	0.0048860158	4.034686e-01	6.311085e-01	3	185623998	185624082	85	+	2.118	2.108	-0.033
ENSG00000163904	E035	137.6951142	0.0007678234	6.813379e-01	8.234849e-01	3	185626298	185626393	96	+	2.121	2.133	0.040
ENSG00000163904	E036	1.3463637	0.0137873557	3.156713e-02		3	185628527	185628600	74	+	0.170	0.557	2.439
ENSG00000163904	E037	705.5188158	0.0037267262	9.667156e-08	3.600231e-06	3	185629782	185632377	2596	+	2.762	2.932	0.563
ENSG00000163904	E038	58.6573716	0.0074024446	2.060661e-11	1.680071e-09	3	185632378	185632667	290	+	1.550	1.981	1.456
ENSG00000163904	E039	134.5128905	0.0024976005	3.783655e-26	2.106727e-23	3	185632668	185633551	884	+	1.907	2.332	1.422

Isoforom Switch Analysis

WANG Ziyi

Date: 19 5月 2022

ENSG00000163904

1 Isoform Switch

TableFilter v0.7.3

2 Differential Exon Usage

TableFilter v0.7.3