ENSG00000163902

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000296255 ENSG00000163902 HEK293_OSMI2_6hA HEK293_TMG_6hB RPN1 protein_coding protein_coding 268.28 190.8806 262.4909 33.64583 9.367635 0.4595762 262.865190 189.8257906 243.97056 33.8888139 6.246255 0.3620142 0.98017917 0.993466667 0.93063333 -0.06283333 0.002088002 0.0004099313 FALSE  
MSTRG.23636.3 ENSG00000163902 HEK293_OSMI2_6hA HEK293_TMG_6hB RPN1 protein_coding   268.28 190.8806 262.4909 33.64583 9.367635 0.4595762 3.553057 0.1789956 16.19857 0.1789956 6.861769 6.4222601 0.01277083 0.001433333 0.06043333 0.05900000 0.024077090 0.0004099313 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_6hB HEK293_OSMI2_6hA log2fold_HEK293_OSMI2_6hA_HEK293_TMG_6hB
ENSG00000163902 E001 452.4007310 6.707954e-03 2.219395e-03 1.852015e-02 3 128619969 128620158 190 - 2.575 2.726 0.504
ENSG00000163902 E002 2917.3192635 7.305682e-04 5.496471e-12 4.962399e-10 3 128620159 128620593 435 - 3.405 3.518 0.376
ENSG00000163902 E003 3012.6870407 3.072037e-04 1.854011e-07 6.445316e-06 3 128622164 128622409 246 - 3.439 3.510 0.238
ENSG00000163902 E004 1950.1791173 1.217174e-04 8.928994e-10 5.266928e-08 3 128625534 128625653 120 - 3.247 3.318 0.236
ENSG00000163902 E005 1633.4987539 6.052867e-04 1.615602e-08 7.235400e-07 3 128625874 128625973 100 - 3.158 3.259 0.336
ENSG00000163902 E006 1255.3997892 4.461610e-04 7.948808e-04 8.240586e-03 3 128625974 128626012 39 - 3.062 3.125 0.212
ENSG00000163902 E007 1638.1214771 4.280504e-04 5.546448e-01 7.395370e-01 3 128626733 128626832 100 - 3.196 3.223 0.087
ENSG00000163902 E008 6.2805142 1.596057e-02 9.551133e-01 9.794865e-01 3 128626833 128627266 434 - 0.849 0.858 0.036
ENSG00000163902 E009 2164.2251047 3.402758e-04 1.691132e-01 3.894218e-01 3 128629951 128630143 193 - 3.328 3.332 0.014
ENSG00000163902 E010 2043.6012609 2.160832e-04 5.692094e-04 6.301490e-03 3 128631948 128632120 173 - 3.313 3.295 -0.059
ENSG00000163902 E011 1079.7452651 1.935569e-04 3.264122e-08 1.360636e-06 3 128632121 128632157 37 - 3.052 2.997 -0.183
ENSG00000163902 E012 898.4522549 9.360845e-05 4.380636e-13 4.808874e-11 3 128637799 128637819 21 - 2.982 2.903 -0.262
ENSG00000163902 E013 2376.1629098 1.000983e-04 3.104366e-38 4.665422e-35 3 128637820 128638037 218 - 3.411 3.317 -0.310
ENSG00000163902 E014 1340.7358210 8.586863e-05 2.997668e-30 2.424157e-27 3 128638038 128638105 68 - 3.167 3.060 -0.356
ENSG00000163902 E015 1.2036270 7.311577e-02 6.172471e-01   3 128641046 128641134 89 - 0.400 0.305 -0.570
ENSG00000163902 E016 0.3032425 2.744240e-02 1.748660e-01   3 128642293 128642564 272 - 0.000 0.226 12.499
ENSG00000163902 E017 0.0000000       3 128644515 128644534 20 -      
ENSG00000163902 E018 1.5795434 3.571474e-02 2.925161e-01 5.331813e-01 3 128644535 128644646 112 - 0.494 0.307 -1.044
ENSG00000163902 E019 0.3040503 2.744240e-02 2.321090e-01   3 128644647 128644650 4 - 0.206 0.000 -12.188
ENSG00000163902 E020 0.3040503 2.744240e-02 2.321090e-01   3 128644651 128644918 268 - 0.206 0.000 -12.188
ENSG00000163902 E021 1327.6098650 8.497383e-05 9.289317e-15 1.374164e-12 3 128644919 128644983 65 - 3.146 3.078 -0.228
ENSG00000163902 E022 1.9261433 6.493949e-01 4.388396e-01 6.578430e-01 3 128647437 128647512 76 - 0.387 0.559 0.869
ENSG00000163902 E023 1740.0309176 2.461757e-04 4.481217e-01 6.643216e-01 3 128650540 128650874 335 - 3.230 3.239 0.027
ENSG00000163902 E024 0.3206185 2.744240e-02 2.318887e-01   3 128651373 128651529 157 - 0.206 0.000 -12.190
ENSG00000163902 E025 2.1587396 5.739317e-01 2.084060e-01 4.399270e-01 3 128680754 128681075 322 - 0.290 0.655 1.890