ENSG00000163597

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000364968 ENSG00000163597 HEK293_OSMI2_6hA HEK293_TMG_6hB SNHG16 lncRNA snoRNA 120.3648 123.8908 86.12065 22.66959 5.576078 -0.5245871 6.767331 5.098619 6.604857 2.776322 3.4643382 0.3727766 0.06602083 0.04373333 0.07323333 0.02950000 9.816992e-01 1.624555e-37   FALSE
ENST00000586942 ENSG00000163597 HEK293_OSMI2_6hA HEK293_TMG_6hB SNHG16 lncRNA lncRNA 120.3648 123.8908 86.12065 22.66959 5.576078 -0.5245871 3.466750 0.000000 7.995139 0.000000 0.7536789 9.6447827 0.04082917 0.00000000 0.09306667 0.09306667 1.624555e-37 1.624555e-37   FALSE
ENST00000590435 ENSG00000163597 HEK293_OSMI2_6hA HEK293_TMG_6hB SNHG16 lncRNA lncRNA 120.3648 123.8908 86.12065 22.66959 5.576078 -0.5245871 20.202838 10.701617 0.000000 5.366378 0.0000000 -10.0649605 0.10542083 0.07456667 0.00000000 -0.07456667 3.017012e-01 1.624555e-37   FALSE
ENST00000661348 ENSG00000163597 HEK293_OSMI2_6hA HEK293_TMG_6hB SNHG16 lncRNA lncRNA 120.3648 123.8908 86.12065 22.66959 5.576078 -0.5245871 56.357096 71.207757 36.810796 16.172347 1.8101689 -0.9517162 0.45677083 0.56276667 0.43070000 -0.13206667 3.690492e-01 1.624555e-37   FALSE
ENST00000670737 ENSG00000163597 HEK293_OSMI2_6hA HEK293_TMG_6hB SNHG16 lncRNA lncRNA 120.3648 123.8908 86.12065 22.66959 5.576078 -0.5245871 20.282449 25.301918 19.444530 2.480136 0.5462963 -0.3797107 0.19966250 0.21400000 0.22683333 0.01283333 9.469760e-01 1.624555e-37   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_6hB HEK293_OSMI2_6hA log2fold_HEK293_OSMI2_6hA_HEK293_TMG_6hB
ENSG00000163597 E001 0.3447487 0.68560919 6.445521e-01   17 76557733 76557756 24 + 0.000 0.190 16.812
ENSG00000163597 E002 0.3447487 0.68560919 6.445521e-01   17 76557757 76557765 9 + 0.000 0.190 16.815
ENSG00000163597 E003 0.3447487 0.68560919 6.445521e-01   17 76557766 76557766 1 + 0.000 0.190 16.815
ENSG00000163597 E004 1.4892881 0.13609151 3.714155e-02 1.472894e-01 17 76557767 76557768 2 + 0.000 0.508 18.833
ENSG00000163597 E005 3.0806476 0.05195830 6.229477e-01 7.858070e-01 17 76557769 76557777 9 + 0.470 0.654 0.847
ENSG00000163597 E006 187.3661401 0.01775137 3.003631e-03 2.341907e-02 17 76557778 76557791 14 + 2.304 2.239 -0.216
ENSG00000163597 E007 226.4427733 0.01898202 8.143140e-03 4.998708e-02 17 76557792 76557795 4 + 2.374 2.330 -0.148
ENSG00000163597 E008 477.3520952 0.01649645 5.946198e-03 3.947741e-02 17 76557796 76557857 62 + 2.686 2.661 -0.084
ENSG00000163597 E009 34.8581697 0.27465067 1.177389e-02 6.552869e-02 17 76557858 76557969 112 + 1.754 1.316 -1.500
ENSG00000163597 E010 43.9385310 0.24163661 5.264006e-03 3.600279e-02 17 76557970 76558279 310 + 1.861 1.396 -1.582
ENSG00000163597 E011 20.6148934 0.12179565 2.994224e-04 3.723823e-03 17 76558280 76558373 94 + 1.561 1.037 -1.839
ENSG00000163597 E012 73.9178628 0.04529775 1.954231e-06 5.115187e-05 17 76558374 76558600 227 + 2.059 1.662 -1.339
ENSG00000163597 E013 35.4173912 0.10836770 4.214900e-04 4.939364e-03 17 76558601 76558790 190 + 1.764 1.314 -1.541
ENSG00000163597 E014 36.1302299 0.09812064 2.702329e-03 2.158292e-02 17 76558791 76558944 154 + 1.731 1.389 -1.170
ENSG00000163597 E015 209.5792977 0.02191368 2.099621e-02 9.933605e-02 17 76558945 76559043 99 + 2.334 2.301 -0.108
ENSG00000163597 E016 57.7158094 0.17998836 2.701759e-02 1.183504e-01 17 76559044 76560433 1390 + 1.905 1.626 -0.944
ENSG00000163597 E017 3.0873836 0.30441182 3.737104e-01 6.071193e-01 17 76561043 76561097 55 + 0.663 0.543 -0.530
ENSG00000163597 E018 357.1304879 0.01464122 1.614503e-02 8.230907e-02 17 76561288 76561293 6 + 2.546 2.546 0.001
ENSG00000163597 E019 638.3629308 0.01416987 1.581235e-02 8.112936e-02 17 76561294 76561398 105 + 2.790 2.802 0.037
ENSG00000163597 E020 21.3160405 0.04335222 8.066273e-01 9.001023e-01 17 76561399 76561402 4 + 1.277 1.379 0.354
ENSG00000163597 E021 28.0996429 0.16053167 1.076290e-01 2.950736e-01 17 76561403 76561633 231 + 1.534 1.392 -0.492
ENSG00000163597 E022 18.0514616 0.15409014 1.418762e-01 3.502725e-01 17 76561634 76561751 118 + 1.354 1.204 -0.525
ENSG00000163597 E023 1153.8010342 0.01466456 1.843992e-03 1.601638e-02 17 76563119 76563482 364 + 3.060 3.049 -0.036
ENSG00000163597 E024 987.9582076 0.00123266 2.899495e-04 3.628212e-03 17 76563483 76563972 490 + 2.948 3.011 0.211
ENSG00000163597 E025 2837.5969945 2.00334319 3.375520e-01 5.759305e-01 17 76563973 76565357 1385 + 3.109 3.578 1.561