ENSG00000163320

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000309534 ENSG00000163320 HEK293_OSMI2_6hA HEK293_TMG_6hB CGGBP1 protein_coding protein_coding 52.30656 23.29786 79.81431 4.250589 1.517257 1.776012 15.655299 4.7478808 27.282262 1.45155246 0.3061632 2.52010092 0.26315833 0.19263333 0.34203333 0.149400000 1.414516e-01 4.719033e-10 FALSE TRUE
ENST00000398392 ENSG00000163320 HEK293_OSMI2_6hA HEK293_TMG_6hB CGGBP1 protein_coding protein_coding 52.30656 23.29786 79.81431 4.250589 1.517257 1.776012 2.380740 0.3573466 5.537296 0.04677052 0.0193768 3.91657102 0.03530833 0.01736667 0.06943333 0.052066667 3.257161e-03 4.719033e-10 FALSE TRUE
ENST00000462901 ENSG00000163320 HEK293_OSMI2_6hA HEK293_TMG_6hB CGGBP1 protein_coding protein_coding 52.30656 23.29786 79.81431 4.250589 1.517257 1.776012 6.566323 1.3189272 11.839484 0.12879160 0.7530158 3.15649029 0.11313333 0.06346667 0.14813333 0.084666667 1.072205e-01 4.719033e-10 FALSE TRUE
ENST00000474441 ENSG00000163320 HEK293_OSMI2_6hA HEK293_TMG_6hB CGGBP1 protein_coding processed_transcript 52.30656 23.29786 79.81431 4.250589 1.517257 1.776012 3.739201 0.9626053 6.590040 0.44358698 0.1837749 2.76254842 0.06644167 0.05376667 0.08260000 0.028833333 6.633188e-01 4.719033e-10   FALSE
ENST00000482016 ENSG00000163320 HEK293_OSMI2_6hA HEK293_TMG_6hB CGGBP1 protein_coding protein_coding 52.30656 23.29786 79.81431 4.250589 1.517257 1.776012 5.492793 2.0720597 7.657912 0.44623273 0.5653323 1.88082227 0.10072917 0.08753333 0.09610000 0.008566667 9.199248e-01 4.719033e-10 FALSE TRUE
ENST00000675130 ENSG00000163320 HEK293_OSMI2_6hA HEK293_TMG_6hB CGGBP1 protein_coding protein_coding 52.30656 23.29786 79.81431 4.250589 1.517257 1.776012 13.676479 13.1617723 12.479117 3.06941470 1.5067530 -0.07677799 0.35337083 0.55316667 0.15586667 -0.397300000 4.719033e-10 4.719033e-10 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_6hB HEK293_OSMI2_6hA log2fold_HEK293_OSMI2_6hA_HEK293_TMG_6hB
ENSG00000163320 E001 0.1779838 0.0363143278 1.000000e+00   3 88051944 88051949 6 - 0.075 0.000 -9.067
ENSG00000163320 E002 0.7614362 0.5712071836 3.508243e-01   3 88051950 88052011 62 - 0.142 0.339 1.605
ENSG00000163320 E003 1973.4457852 0.0072432910 1.651037e-11 1.369062e-09 3 88052012 88055322 3311 - 3.294 3.017 -0.923
ENSG00000163320 E004 169.1574342 0.0002987171 2.274827e-10 1.495617e-08 3 88055323 88055425 103 - 2.239 1.904 -1.124
ENSG00000163320 E005 443.4478212 0.0001778208 8.049864e-07 2.352120e-05 3 88055426 88055657 232 - 2.591 2.583 -0.027
ENSG00000163320 E006 648.2773846 0.0002405831 4.749141e-35 5.639954e-32 3 88055658 88055999 342 - 2.729 2.817 0.295
ENSG00000163320 E007 90.0154487 0.0477193530 1.456468e-03 1.331502e-02 3 88056000 88057190 1191 - 1.986 1.479 -1.719
ENSG00000163320 E008 59.5507104 0.0008549812 8.748089e-01 9.386485e-01 3 88057191 88057292 102 - 1.751 1.640 -0.376
ENSG00000163320 E009 11.6278676 0.0136705627 2.260483e-03 1.880116e-02 3 88057293 88057309 17 - 1.135 0.576 -2.193
ENSG00000163320 E010 39.9151841 0.0009066273 4.747716e-13 5.185024e-11 3 88057638 88058018 381 - 1.661 0.883 -2.753
ENSG00000163320 E011 354.7974391 0.0010478187 1.827443e-16 3.380629e-14 3 88058019 88058138 120 - 2.466 2.563 0.323
ENSG00000163320 E012 265.7222942 0.0017278191 1.007011e-11 8.641417e-10 3 88058139 88058223 85 - 2.341 2.439 0.327
ENSG00000163320 E013 7.1172717 0.0050653014 6.969632e-01 8.335943e-01 3 88058373 88058451 79 - 0.880 0.735 -0.571
ENSG00000163320 E014 178.6743483 0.0013738167 1.380421e-19 3.830511e-17 3 88058815 88059048 234 - 2.138 2.329 0.638
ENSG00000163320 E015 37.6282566 0.2208726530 7.316460e-01 8.552591e-01 3 88140970 88141078 109 - 1.587 1.312 -0.949
ENSG00000163320 E016 5.9115517 0.0172532143 8.722238e-01 9.371392e-01 3 88149300 88149567 268 - 0.798 0.735 -0.253
ENSG00000163320 E017 7.5875258 0.0076011330 2.072261e-01 4.384937e-01 3 88149568 88149710 143 - 0.868 0.942 0.278
ENSG00000163320 E018 23.8024417 0.0214816546 2.973806e-02 1.265672e-01 3 88149711 88149885 175 - 1.410 1.041 -1.307