ENSG00000162885

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000366600 ENSG00000162885 HEK293_OSMI2_6hA HEK293_TMG_6hB B3GALNT2 protein_coding protein_coding 16.25899 8.664211 24.1194 0.4980867 1.233475 1.475988 10.1742419 5.1650677 14.9449238 0.74125677 0.5462285 1.5309709 0.61240000 0.59340000 0.62100000 0.0276000000 9.638650e-01 1.439624e-08 FALSE TRUE
ENST00000462374 ENSG00000162885 HEK293_OSMI2_6hA HEK293_TMG_6hB B3GALNT2 protein_coding processed_transcript 16.25899 8.664211 24.1194 0.4980867 1.233475 1.475988 0.9016977 0.8635267 2.4481998 0.43281699 0.6863624 1.4926785 0.05974167 0.09986667 0.09900000 -0.0008666667 9.488433e-01 1.439624e-08   FALSE
ENST00000675555 ENSG00000162885 HEK293_OSMI2_6hA HEK293_TMG_6hB B3GALNT2 protein_coding protein_coding 16.25899 8.664211 24.1194 0.4980867 1.233475 1.475988 1.0235104 0.0000000 2.1716684 0.00000000 0.5049697 7.7692881 0.04242500 0.00000000 0.08843333 0.0884333333 1.439624e-08 1.439624e-08 FALSE TRUE
MSTRG.3338.2 ENSG00000162885 HEK293_OSMI2_6hA HEK293_TMG_6hB B3GALNT2 protein_coding   16.25899 8.664211 24.1194 0.4980867 1.233475 1.475988 1.7386835 1.4375543 0.8419653 0.08015208 0.4778373 -0.7647509 0.13172083 0.16596667 0.03310000 -0.1328666667 3.367185e-01 1.439624e-08 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_6hB HEK293_OSMI2_6hA log2fold_HEK293_OSMI2_6hA_HEK293_TMG_6hB
ENSG00000162885 E001 0.7119354 1.3937695613 0.69095624   1 235447031 235447091 61 - 0.289 0.000 -10.593
ENSG00000162885 E002 0.7119354 1.3937695613 0.69095624   1 235447092 235447189 98 - 0.289 0.000 -10.550
ENSG00000162885 E003 295.7828405 0.0185013251 0.26631031 0.50582168 1 235447190 235448250 1061 - 2.404 2.515 0.370
ENSG00000162885 E004 84.4793198 0.1145727682 0.21153829 0.44361107 1 235448251 235448424 174 - 1.844 2.009 0.555
ENSG00000162885 E005 161.2995411 1.4180891362 0.53135327 0.72299005 1 235448425 235449090 666 - 2.135 2.264 0.432
ENSG00000162885 E006 42.0247933 0.7185342637 0.49788191 0.69941681 1 235449091 235449154 64 - 1.580 1.655 0.254
ENSG00000162885 E007 200.4936915 1.5134762087 0.61174643 0.77804173 1 235449155 235450010 856 - 2.254 2.315 0.203
ENSG00000162885 E008 87.3476938 1.2030180366 0.56192039 0.74463342 1 235450011 235450239 229 - 1.893 1.964 0.238
ENSG00000162885 E009 78.8813553 0.9203866925 0.51985954 0.71491351 1 235450240 235450340 101 - 1.851 1.917 0.225
ENSG00000162885 E010 5.4691565 0.1699642854 0.69977085 0.83548127 1 235450341 235451374 1034 - 0.773 0.827 0.213
ENSG00000162885 E011 77.0331229 0.0174789551 0.93423238 0.96925318 1 235453090 235453146 57 - 1.865 1.869 0.012
ENSG00000162885 E012 1.2886807 0.3774626585 0.84818312   1 235454021 235454155 135 - 0.328 0.377 0.292
ENSG00000162885 E013 107.1951958 0.0003708468 0.06460977 0.21302349 1 235454156 235454286 131 - 2.023 1.982 -0.138
ENSG00000162885 E014 62.9120175 0.0146778073 0.84923634 0.92452186 1 235454287 235454315 29 - 1.769 1.794 0.084
ENSG00000162885 E015 110.5793758 0.0089205418 0.65411759 0.80615971 1 235455559 235455684 126 - 2.016 2.028 0.040
ENSG00000162885 E016 0.8855973 0.0202299554 0.10098261   1 235457034 235457103 70 - 0.158 0.461 2.107
ENSG00000162885 E017 0.6901176 0.0588275693 0.09394013   1 235457166 235457251 86 - 0.086 0.386 2.711
ENSG00000162885 E018 97.6976853 0.0042996725 0.36126036 0.59672913 1 235458603 235458786 184 - 1.971 1.960 -0.037
ENSG00000162885 E019 8.0436369 0.0942368368 0.22322894 0.45723310 1 235463458 235464895 1438 - 0.980 0.797 -0.697
ENSG00000162885 E020 7.6694017 0.1658469024 0.95424879 0.97903317 1 235464896 235465635 740 - 0.909 0.898 -0.040
ENSG00000162885 E021 80.2364164 0.0095578696 0.75422333 0.86925698 1 235465636 235465714 79 - 1.877 1.890 0.045
ENSG00000162885 E022 121.5524906 0.0328232062 0.63996978 0.79686762 1 235470850 235470960 111 - 2.061 2.054 -0.021
ENSG00000162885 E023 17.4597087 0.0208038387 0.38941335 0.61999103 1 235478908 235480053 1146 - 1.190 1.314 0.435
ENSG00000162885 E024 102.4400798 0.0474238074 0.39150874 0.62163703 1 235480054 235480103 50 - 2.003 1.943 -0.201
ENSG00000162885 E025 99.6616861 0.0436558873 0.26146640 0.50055811 1 235480104 235480149 46 - 1.999 1.914 -0.285
ENSG00000162885 E026 164.7240742 0.0230342943 0.15093762 0.36364600 1 235484322 235484504 183 - 2.211 2.142 -0.233
ENSG00000162885 E027 68.3284726 0.0152676180 0.09742030 0.27726637 1 235484505 235484515 11 - 1.839 1.750 -0.298
ENSG00000162885 E028 5.9645251 0.1444865091 0.47614917 0.68434707 1 235484516 235485264 749 - 0.732 0.945 0.831
ENSG00000162885 E029 95.8385448 0.0102351469 0.01681466 0.08478374 1 235489168 235489268 101 - 1.991 1.882 -0.368
ENSG00000162885 E030 80.9058474 0.0214454102 0.37895818 0.61136954 1 235494681 235494828 148 - 1.894 1.866 -0.094
ENSG00000162885 E031 12.9362957 0.0447196303 0.13076404 0.33299456 1 235496186 235496308 123 - 1.022 1.259 0.851
ENSG00000162885 E032 0.0000000       1 235498719 235498827 109 -      
ENSG00000162885 E033 1.8174392 0.0143308542 0.39836252 0.62695395 1 235503857 235504140 284 - 0.365 0.528 0.852
ENSG00000162885 E034 30.7431774 0.0352389737 0.02053897 0.09782063 1 235504141 235504452 312 - 1.355 1.646 1.000