ENSG00000160932

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000292494 ENSG00000160932 HEK293_OSMI2_6hA HEK293_TMG_6hB LY6E protein_coding protein_coding 229.3734 349.5567 124.0203 56.31317 4.350192 -1.494876 102.21472 139.08938 62.64722 19.58774 1.8569081 -1.150563 0.4547292 0.4008000 0.5053333 0.10453333 0.001328131 0.001328131 FALSE FALSE
ENST00000429120 ENSG00000160932 HEK293_OSMI2_6hA HEK293_TMG_6hB LY6E protein_coding protein_coding 229.3734 349.5567 124.0203 56.31317 4.350192 -1.494876 75.15652 120.36635 38.41764 22.79867 1.7841704 -1.647336 0.3224500 0.3416667 0.3095333 -0.03213333 0.664634300 0.001328131 FALSE TRUE
MSTRG.32180.2 ENSG00000160932 HEK293_OSMI2_6hA HEK293_TMG_6hB LY6E protein_coding   229.3734 349.5567 124.0203 56.31317 4.350192 -1.494876 38.55377 70.73961 16.36592 12.17825 0.9767137 -2.111146 0.1645750 0.2014000 0.1321333 -0.06926667 0.015584655 0.001328131 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_6hB HEK293_OSMI2_6hA log2fold_HEK293_OSMI2_6hA_HEK293_TMG_6hB
ENSG00000160932 E001 0.00000       8 143017982 143018247 266 +      
ENSG00000160932 E002 31.58894 6.138300e-03 1.985943e-08 8.712446e-07 8 143018467 143018482 16 + 0.896 1.507 2.180
ENSG00000160932 E003 309.22914 2.312261e-03 1.541155e-05 3.053238e-04 8 143018483 143018516 34 + 2.283 2.430 0.492
ENSG00000160932 E004 422.37464 1.109694e-03 3.163228e-08 1.323125e-06 8 143018517 143018527 11 + 2.419 2.566 0.490
ENSG00000160932 E005 424.70260 9.772465e-04 1.298451e-08 5.933985e-07 8 143018528 143018528 1 + 2.421 2.568 0.492
ENSG00000160932 E006 527.86974 1.967891e-04 8.739885e-05 1.335103e-03 8 143018529 143018541 13 + 2.578 2.653 0.249
ENSG00000160932 E007 530.78287 2.026497e-04 8.606103e-05 1.318580e-03 8 143018542 143018543 2 + 2.581 2.655 0.248
ENSG00000160932 E008 581.10660 6.006284e-04 5.098256e-04 5.768547e-03 8 143018544 143018545 2 + 2.622 2.692 0.234
ENSG00000160932 E009 714.18102 2.824969e-04 1.138543e-03 1.095658e-02 8 143018546 143018551 6 + 2.726 2.780 0.179
ENSG00000160932 E010 707.09298 2.042921e-04 1.066997e-03 1.042701e-02 8 143018552 143018552 1 + 2.723 2.776 0.176
ENSG00000160932 E011 748.45726 1.273728e-04 1.135545e-03 1.093330e-02 8 143018553 143018556 4 + 2.751 2.800 0.164
ENSG00000160932 E012 868.32820 1.053217e-04 4.773826e-04 5.471489e-03 8 143018557 143018586 30 + 2.815 2.864 0.162
ENSG00000160932 E013 12.86213 2.638337e-03 3.471563e-01 5.846676e-01 8 143018833 143019119 287 + 1.149 1.047 -0.370
ENSG00000160932 E014 25.59420 1.526541e-02 9.310606e-01 9.675525e-01 8 143020262 143020377 116 + 1.358 1.333 -0.088
ENSG00000160932 E015 554.70507 1.220420e-04 6.791769e-02 2.204129e-01 8 143020883 143020887 5 + 2.635 2.665 0.099
ENSG00000160932 E016 901.21612 8.977183e-05 5.978123e-01 7.688206e-01 8 143020888 143020916 29 + 2.880 2.868 -0.041
ENSG00000160932 E017 1447.26138 1.906149e-04 8.180537e-03 5.015500e-02 8 143020917 143020991 75 + 3.105 3.064 -0.134
ENSG00000160932 E018 836.80054 1.231800e-04 8.811341e-07 2.544844e-05 8 143021314 143021317 4 + 2.898 2.819 -0.262
ENSG00000160932 E019 1122.44839 4.017997e-04 2.695430e-04 3.422232e-03 8 143021318 143021348 31 + 3.013 2.948 -0.217
ENSG00000160932 E020 1773.52627 1.185853e-04 1.202819e-04 1.741401e-03 8 143021349 143021433 85 + 3.200 3.152 -0.159
ENSG00000160932 E021 11.37455 5.923400e-02 5.249524e-01 7.184509e-01 8 143021434 143021548 115 + 0.929 1.018 0.333
ENSG00000160932 E022 21.11777 3.491393e-03 6.788435e-01 8.220132e-01 8 143021549 143021565 17 + 1.236 1.270 0.120
ENSG00000160932 E023 4421.28243 7.515055e-04 3.638822e-03 2.714260e-02 8 143021566 143022120 555 + 3.593 3.545 -0.159
ENSG00000160932 E024 1409.24486 6.723069e-05 5.730579e-04 6.336247e-03 8 143022121 143022200 80 + 3.099 3.055 -0.147
ENSG00000160932 E025 991.47801 1.816735e-03 8.624779e-01 9.317025e-01 8 143022201 143022411 211 + 2.913 2.906 -0.025
ENSG00000160932 E026 11.73462 1.969137e-02 9.763833e-01 9.899540e-01 8 143022549 143023042 494 + 1.040 1.026 -0.052
ENSG00000160932 E027 13.89705 2.347198e-03 3.468958e-01 5.844706e-01 8 143023669 143023832 164 + 1.168 1.067 -0.365