ENSG00000160767

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000350210 ENSG00000160767 HEK293_OSMI2_6hA HEK293_TMG_6hB FAM189B protein_coding protein_coding 72.8151 108.6092 44.29947 19.83806 2.291761 -1.293593 23.05249 36.606495 10.796410 6.7892055 0.6560068 -1.7606064 0.3109083 0.33720000 0.2436333 -0.09356667 0.003799116 0.003799116 FALSE  
ENST00000361361 ENSG00000160767 HEK293_OSMI2_6hA HEK293_TMG_6hB FAM189B protein_coding protein_coding 72.8151 108.6092 44.29947 19.83806 2.291761 -1.293593 26.82608 47.192107 20.288037 10.5114045 0.8501290 -1.2175111 0.3766333 0.42616667 0.4584333 0.03226667 0.832092429 0.003799116 FALSE  
ENST00000368366 ENSG00000160767 HEK293_OSMI2_6hA HEK293_TMG_6hB FAM189B protein_coding retained_intron 72.8151 108.6092 44.29947 19.83806 2.291761 -1.293593 11.60809 6.656691 4.778675 0.4786814 0.3714698 -0.4773442 0.1469042 0.06553333 0.1082000 0.04266667 0.335922941 0.003799116 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_6hB HEK293_OSMI2_6hA log2fold_HEK293_OSMI2_6hA_HEK293_TMG_6hB
ENSG00000160767 E001 12.05551 0.13567196 0.350215537 0.587421386 1 155247205 155247216 12 - 0.883 1.105 0.822
ENSG00000160767 E002 383.36350 1.14991475 0.479770017 0.686923393 1 155247217 155247361 145 - 2.389 2.558 0.563
ENSG00000160767 E003 528.56075 1.28859130 0.525657204 0.718974070 1 155247362 155247426 65 - 2.549 2.692 0.476
ENSG00000160767 E004 406.66726 1.20631033 0.536918363 0.726975823 1 155247427 155247440 14 - 2.453 2.574 0.405
ENSG00000160767 E005 417.11503 1.20822062 0.524653323 0.718238477 1 155247441 155247447 7 - 2.455 2.588 0.443
ENSG00000160767 E006 419.16052 1.19935548 0.508634713 0.706902366 1 155247448 155247455 8 - 2.445 2.593 0.493
ENSG00000160767 E007 471.11896 1.23565528 0.502574503 0.702574167 1 155247456 155247473 18 - 2.486 2.645 0.529
ENSG00000160767 E008 445.21823 1.19835437 0.474413773 0.683136364 1 155247474 155247489 16 - 2.443 2.625 0.605
ENSG00000160767 E009 524.57958 1.25330470 0.472905571 0.682092413 1 155247490 155247526 37 - 2.507 2.697 0.634
ENSG00000160767 E010 1517.44593 1.61495004 0.491969420 0.695292995 1 155247527 155247955 429 - 2.945 3.163 0.725
ENSG00000160767 E011 376.51474 1.03040664 0.319941874 0.559654411 1 155248050 155248073 24 - 2.258 2.573 1.052
ENSG00000160767 E012 959.45882 1.44063754 0.450208440 0.665845834 1 155248074 155248303 230 - 2.731 2.967 0.784
ENSG00000160767 E013 511.14864 0.01130697 0.246786117 0.484457787 1 155248405 155248473 69 - 2.553 2.675 0.404
ENSG00000160767 E014 643.95615 0.01758244 0.788881367 0.889814292 1 155250276 155250587 312 - 2.650 2.775 0.414
ENSG00000160767 E015 449.19887 0.04138766 0.794849066 0.893243282 1 155250588 155250693 106 - 2.521 2.611 0.299
ENSG00000160767 E016 539.62960 0.03917947 0.260823024 0.499824977 1 155250694 155250821 128 - 2.664 2.672 0.026
ENSG00000160767 E017 16.14950 0.14745431 0.051555989 0.183435842 1 155250822 155250929 108 - 1.369 1.081 -1.019
ENSG00000160767 E018 545.84003 0.03794888 0.074498988 0.233817693 1 155251095 155251164 70 - 2.714 2.661 -0.176
ENSG00000160767 E019 526.34613 0.04376480 0.082822551 0.250368009 1 155251502 155251601 100 - 2.705 2.643 -0.207
ENSG00000160767 E020 12.25383 0.19792304 0.021392784 0.100630638 1 155251602 155251732 131 - 1.322 0.924 -1.434
ENSG00000160767 E021 573.43640 0.04803361 0.126601144 0.326416510 1 155251733 155251905 173 - 2.732 2.684 -0.161
ENSG00000160767 E022 33.79506 0.01789234 0.082906838 0.250551446 1 155251906 155251908 3 - 1.539 1.456 -0.284
ENSG00000160767 E023 10.50863 0.12390869 0.037694537 0.148817840 1 155251909 155252068 160 - 1.203 0.907 -1.081
ENSG00000160767 E024 38.80816 0.15157909 0.000462472 0.005331865 1 155252749 155253624 876 - 1.890 1.308 -1.989
ENSG00000160767 E025 539.84353 0.03670295 0.083732928 0.252244461 1 155253625 155253732 108 - 2.705 2.658 -0.158
ENSG00000160767 E026 360.05133 0.04610677 0.038914655 0.151949863 1 155253859 155253978 120 - 2.572 2.466 -0.353
ENSG00000160767 E027 362.17694 0.04564492 0.037671907 0.148769998 1 155254084 155254194 111 - 2.576 2.467 -0.361
ENSG00000160767 E028 238.36635 0.04803198 0.095754609 0.274343574 1 155254400 155254456 57 - 2.368 2.297 -0.236
ENSG00000160767 E029 14.35354 0.02747760 0.089542181 0.262971409 1 155254457 155254535 79 - 1.230 1.090 -0.499
ENSG00000160767 E030 1286.17467 0.05552983 0.748176775 0.865607819 1 155254653 155255579 927 - 2.981 3.066 0.283