ENSG00000159314

1 Isoform Switch

Summary Plot
Results

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Rows: 1-6 / 6
Columns:
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isoform_id
gene_id
condition_1
condition_2
gene_name
gene_biotype
iso_biotype
gene_overall_mean
gene_value_1
gene_value_2
gene_stderr_1
gene_stderr_2
gene_log2_fold_change
iso_overall_mean
iso_value_1
iso_value_2
iso_stderr_1
iso_stderr_2
iso_log2_fold_change
IF_overall
IF1
IF2
dIF
isoform_switch_q_value
gene_switch_q_value
PTC
codingPotential
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isoform_id	gene_id	condition_1	condition_2	gene_name	gene_biotype	iso_biotype	gene_overall_mean	gene_value_1	gene_value_2	gene_stderr_1	gene_stderr_2	gene_log2_fold_change	iso_overall_mean	iso_value_1	iso_value_2	iso_stderr_1	iso_stderr_2	iso_log2_fold_change	IF_overall	IF1	IF2	dIF	isoform_switch_q_value	gene_switch_q_value	PTC	codingPotential

ENST00000376922	ENSG00000159314	HEK293_OSMI2_6hA	HEK293_TMG_6hB	ARHGAP27	protein_coding	protein_coding	4.647991	6.40023	2.410383	0.315893	0.2147279	-1.405141	0.8294936	1.52092287	0.00000000	0.17901938	0.000000000	-7.258258	0.15703333	0.24120000	0.00000000	-0.241200000	1.081681e-07	1.081681e-07	FALSE	TRUE
ENST00000526484	ENSG00000159314	HEK293_OSMI2_6hA	HEK293_TMG_6hB	ARHGAP27	protein_coding	retained_intron	4.647991	6.40023	2.410383	0.315893	0.2147279	-1.405141	0.1206722	0.07850053	0.22329200	0.07850053	0.089198142	1.398379	0.02838750	0.01283333	0.08883333	0.076000000	2.327777e-01	1.081681e-07		FALSE
ENST00000532038	ENSG00000159314	HEK293_OSMI2_6hA	HEK293_TMG_6hB	ARHGAP27	protein_coding	protein_coding	4.647991	6.40023	2.410383	0.315893	0.2147279	-1.405141	2.1055657	2.91834748	1.33952061	0.58429097	0.030329655	-1.117640	0.45881250	0.45106667	0.56716667	0.116100000	7.619615e-01	1.081681e-07	FALSE	TRUE
ENST00000581638	ENSG00000159314	HEK293_OSMI2_6hA	HEK293_TMG_6hB	ARHGAP27	protein_coding	retained_intron	4.647991	6.40023	2.410383	0.315893	0.2147279	-1.405141	0.3278608	0.43962353	0.12443738	0.15933289	0.009197421	-1.741783	0.07229583	0.06810000	0.05203333	-0.016066667	9.410278e-01	1.081681e-07	TRUE	FALSE
ENST00000581991	ENSG00000159314	HEK293_OSMI2_6hA	HEK293_TMG_6hB	ARHGAP27	protein_coding	retained_intron	4.647991	6.40023	2.410383	0.315893	0.2147279	-1.405141	0.3006967	0.19367823	0.07410711	0.09715334	0.074107111	-1.275992	0.06557083	0.03183333	0.03030000	-0.001533333	9.334349e-01	1.081681e-07	FALSE	FALSE
ENST00000590026	ENSG00000159314	HEK293_OSMI2_6hA	HEK293_TMG_6hB	ARHGAP27	protein_coding	retained_intron	4.647991	6.40023	2.410383	0.315893	0.2147279	-1.405141	0.2295554	0.12420600	0.34608497	0.12420600	0.234236393	1.407772	0.05018333	0.02030000	0.12910000	0.108800000	6.063866e-01	1.081681e-07		FALSE

Note:
- The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

All exons whithin this gene region are shown and numbering below.

All isoforms whithin this gene region are shown below.

Rows: 1-10 / 50
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featureID
exonBaseMean
dispersion
pvalue
padj
seqnames
start
end
width
strand
HEK293_TMG_6hB
HEK293_OSMI2_6hA
log2fold_HEK293_OSMI2_6hA_HEK293_TMG_6hB
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groupID	featureID	exonBaseMean	dispersion	pvalue	padj	seqnames	start	end	width	strand	HEK293_TMG_6hB	HEK293_OSMI2_6hA	log2fold_HEK293_OSMI2_6hA_HEK293_TMG_6hB

ENSG00000159314	E001	0.0000000				17	45393902	45393907	6	-
ENSG00000159314	E002	0.0000000				17	45393908	45393908	1	-
ENSG00000159314	E003	0.6486114	0.019197450	0.8002825279		17	45393909	45393938	30	-	0.217	0.171	-0.427
ENSG00000159314	E004	120.5268826	0.000402706	0.9858317939	0.994741585	17	45393939	45394942	1004	-	1.989	1.987	-0.009
ENSG00000159314	E005	61.8545018	0.007237340	0.8113484716	0.903041963	17	45394943	45395246	304	-	1.712	1.691	-0.071
ENSG00000159314	E006	29.3640555	0.005190049	0.1939995553	0.422130365	17	45395247	45395426	180	-	1.470	1.364	-0.367
ENSG00000159314	E007	12.3654249	0.004036480	0.6421810452	0.798286498	17	45395427	45395454	28	-	1.003	1.057	0.197
ENSG00000159314	E008	9.7413775	0.027844369	0.4784770115	0.686057026	17	45395455	45395455	1	-	1.029	0.934	-0.354
ENSG00000159314	E009	28.8078124	0.018268483	0.2240418904	0.458234530	17	45395456	45395633	178	-	1.471	1.361	-0.380
ENSG00000159314	E010	23.7914527	0.001908891	0.5194127785	0.714641791	17	45395744	45395849	106	-	1.350	1.295	-0.191
ENSG00000159314	E011	0.9742192	0.033212201	0.1088496409		17	45395850	45395908	59	-	0.469	0.171	-2.016
ENSG00000159314	E012	21.7388474	0.001658474	0.2869760885	0.527727538	17	45395983	45396062	80	-	1.184	1.282	0.346
ENSG00000159314	E013	17.9210730	0.002021835	0.2301515272	0.465305840	17	45396063	45396117	55	-	1.080	1.202	0.438
ENSG00000159314	E014	1.1298377	0.014276330	0.5881211664		17	45396118	45396163	46	-	0.361	0.256	-0.692
ENSG00000159314	E015	18.8294452	0.002053204	0.0883854964	0.260773991	17	45396207	45396284	78	-	1.056	1.232	0.629
ENSG00000159314	E016	3.7946690	0.021979174	0.7139551197	0.844318753	17	45396285	45396486	202	-	0.556	0.623	0.301
ENSG00000159314	E017	13.9882425	0.003439643	0.5126621897	0.709943824	17	45396487	45396585	99	-	1.030	1.104	0.266
ENSG00000159314	E018	17.9427185	0.002024045	0.5593948257	0.742892392	17	45396668	45396790	123	-	1.145	1.202	0.202
ENSG00000159314	E019	23.0280732	0.147909288	0.3658785092	0.600670089	17	45396916	45397024	109	-	1.174	1.307	0.469
ENSG00000159314	E020	1.6489860	0.012198908	0.4002368630	0.628454905	17	45397205	45397228	24	-	0.217	0.388	1.157
ENSG00000159314	E021	3.1167456	0.125363500	0.5707149138	0.750804333	17	45397514	45397948	435	-	0.625	0.516	-0.499
ENSG00000159314	E022	13.7270558	0.101205699	0.9752657542	0.989481381	17	45397949	45397964	16	-	1.115	1.067	-0.172
ENSG00000159314	E023	23.5878617	0.003953939	0.8592805817	0.929969530	17	45397965	45398047	83	-	1.282	1.294	0.041
ENSG00000159314	E024	2.0045441	0.019998058	0.0007036282	0.007473404	17	45401580	45401668	89	-	0.792	0.216	-3.009
ENSG00000159314	E025	18.3551837	0.001910668	0.1830663442	0.407904846	17	45402714	45402773	60	-	1.080	1.215	0.484
ENSG00000159314	E026	18.9149855	0.002114538	0.0803593028	0.245566334	17	45402774	45402818	45	-	1.056	1.236	0.644
ENSG00000159314	E027	22.3422484	0.001562177	0.3318260019	0.570673112	17	45403619	45403709	91	-	1.202	1.289	0.308
ENSG00000159314	E028	0.5061644	0.290779409	0.5898942671		17	45403710	45404028	319	-	0.217	0.122	-0.997
ENSG00000159314	E029	24.4625832	0.001475575	0.4575124065	0.671431047	17	45404029	45404096	68	-	1.363	1.300	-0.219
ENSG00000159314	E030	0.4812263	0.022578585	0.5636814637		17	45404097	45404186	90	-	0.217	0.121	-1.016
ENSG00000159314	E031	2.7428544	0.048306363	0.4049151094	0.632195446	17	45404269	45404334	66	-	0.361	0.533	0.896
ENSG00000159314	E032	19.1367600	0.002104688	0.0762599748	0.237259949	17	45404445	45404474	30	-	1.337	1.179	-0.557
ENSG00000159314	E033	22.1727787	0.001981324	0.0223686271	0.103801163	17	45404475	45404528	54	-	1.420	1.231	-0.658
ENSG00000159314	E034	0.5657866	0.021674798	0.1817248901		17	45404529	45404600	72	-	0.361	0.121	-2.017
ENSG00000159314	E035	22.5957337	0.004291233	0.2603853527	0.499347641	17	45404601	45404681	81	-	1.363	1.265	-0.341
ENSG00000159314	E036	0.7491197	0.017710250	1.0000000000		17	45404682	45404923	242	-	0.217	0.215	-0.015
ENSG00000159314	E037	20.4405949	0.001808767	0.7803574084	0.884970992	17	45404924	45405027	104	-	1.219	1.244	0.086
ENSG00000159314	E038	18.7003128	0.006941017	0.8796524360	0.941092094	17	45405028	45405106	79	-	1.184	1.195	0.040
ENSG00000159314	E039	20.7230097	0.018583235	0.4958255521	0.698081435	17	45405676	45405846	171	-	1.183	1.255	0.256
ENSG00000159314	E040	22.5985087	0.001939306	0.0745546998	0.233910176	17	45405847	45406083	237	-	1.145	1.313	0.593
ENSG00000159314	E041	0.1614157	0.032225219	0.1070068942		17	45407533	45410231	2699	-	0.217	0.000	-12.434
ENSG00000159314	E042	0.1723744	0.032443085	1.0000000000		17	45410232	45410426	195	-	0.000	0.065	9.120
ENSG00000159314	E043	6.7159108	0.004645455	0.0254461915	0.113582830	17	45425564	45425734	171	-	0.469	0.851	1.650
ENSG00000159314	E044	0.0000000				17	45429352	45429352	1	-
ENSG00000159314	E045	0.2617363	0.113085350	1.0000000000		17	45429353	45429622	270	-	0.000	0.119	9.843
ENSG00000159314	E046	6.9776761	0.005145341	0.5065217237	0.705305335	17	45429623	45430297	675	-	0.743	0.841	0.386
ENSG00000159314	E047	3.1595418	0.008149307	0.9066487897	0.955425788	17	45431621	45431752	132	-	0.556	0.533	-0.106
ENSG00000159314	E048	1.5528021	0.013299980	0.9888607004	0.996257360	17	45432216	45432349	134	-	0.361	0.358	-0.017
ENSG00000159314	E049	4.5101726	0.046254880	0.1739163570	0.395762951	17	45432752	45433746	995	-	0.836	0.607	-0.943
ENSG00000159314	E050	0.9624527	0.099898864	0.4600681498		17	45434310	45434421	112	-	0.363	0.214	-1.035

Isoforom Switch Analysis

WANG Ziyi

Date: 19 5月 2022

ENSG00000159314

1 Isoform Switch

TableFilter v0.7.3

2 Differential Exon Usage

TableFilter v0.7.3