ENSG00000159247

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000290377 ENSG00000159247 HEK293_OSMI2_6hA HEK293_TMG_6hB   transcribed_unprocessed_pseudogene processed_transcript 9.626707 12.56654 7.08421 1.390576 0.5249515 -0.8260208 0.5461488 1.602633 0.0000000 0.6872166 0.00000000 -7.3332747 0.05805417 0.14326667 0.00000000 -0.14326667 0.001835205 0.001835205 FALSE TRUE
ENST00000503395 ENSG00000159247 HEK293_OSMI2_6hA HEK293_TMG_6hB   transcribed_unprocessed_pseudogene processed_transcript 9.626707 12.56654 7.08421 1.390576 0.5249515 -0.8260208 2.7736167 3.141656 2.5285948 0.1485769 0.02773404 -0.3120802 0.30145000 0.25500000 0.36073333 0.10573333 0.367435118 0.001835205 FALSE TRUE
ENST00000508529 ENSG00000159247 HEK293_OSMI2_6hA HEK293_TMG_6hB   transcribed_unprocessed_pseudogene transcribed_unprocessed_pseudogene 9.626707 12.56654 7.08421 1.390576 0.5249515 -0.8260208 1.6579415 1.378301 1.1969769 0.7236174 0.07042596 -0.2019224 0.16812083 0.09936667 0.17010000 0.07073333 0.796895555 0.001835205 FALSE TRUE
MSTRG.33715.12 ENSG00000159247 HEK293_OSMI2_6hA HEK293_TMG_6hB   transcribed_unprocessed_pseudogene   9.626707 12.56654 7.08421 1.390576 0.5249515 -0.8260208 3.2054628 4.074254 2.5139622 0.7118625 0.47721732 -0.6943822 0.31910000 0.31943333 0.34973333 0.03030000 0.922150852 0.001835205 FALSE TRUE
MSTRG.33715.5 ENSG00000159247 HEK293_OSMI2_6hA HEK293_TMG_6hB   transcribed_unprocessed_pseudogene   9.626707 12.56654 7.08421 1.390576 0.5249515 -0.8260208 0.4882409 1.167017 0.2161068 0.2638559 0.01845342 -2.3800591 0.04881250 0.09083333 0.03096667 -0.05986667 0.066191211 0.001835205 FALSE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_6hB HEK293_OSMI2_6hA log2fold_HEK293_OSMI2_6hA_HEK293_TMG_6hB
ENSG00000159247 E001 0.1723744 0.0329562488 1.0000000000   9 138150075 138150089 15 + 0.000 0.086 8.213
ENSG00000159247 E002 1.9952648 0.0760576695 0.0132346622 0.071387079 9 138150090 138150105 16 + 0.000 0.540 13.256
ENSG00000159247 E003 3.2047910 0.0839397083 0.2346791903 0.470480399 9 138150106 138150109 4 + 0.386 0.642 1.240
ENSG00000159247 E004 4.2460068 0.0077298178 0.0888396832 0.261644827 9 138150110 138150112 3 + 0.463 0.749 1.276
ENSG00000159247 E005 9.2497457 0.0800023718 0.1717149782 0.392827448 9 138150113 138150149 37 + 0.762 1.035 1.042
ENSG00000159247 E006 13.4346728 0.0725516314 0.1756849131 0.398043346 9 138150150 138150172 23 + 0.939 1.179 0.874
ENSG00000159247 E007 24.8053007 0.0088882791 0.2379386371 0.474210224 9 138150173 138150308 136 + 1.292 1.405 0.390
ENSG00000159247 E008 1.4933675 0.0136968632 0.5610669141 0.744043133 9 138157352 138157469 118 + 0.290 0.404 0.687
ENSG00000159247 E009 17.2619004 0.0024187749 0.0910583865 0.265587091 9 138174046 138174141 96 + 1.312 1.177 -0.475
ENSG00000159247 E010 34.9979993 0.0026424011 0.0047480829 0.033264591 9 138174142 138174369 228 + 1.631 1.466 -0.565
ENSG00000159247 E011 15.2157955 0.0518987116 0.1459576643 0.356318907 9 138174370 138174372 3 + 1.299 1.122 -0.630
ENSG00000159247 E012 55.1135839 0.0008114413 0.0001262143 0.001813682 9 138174373 138174700 328 + 1.824 1.653 -0.576
ENSG00000159247 E013 38.2091899 0.0014475806 0.1996537427 0.429219910 9 138174701 138174872 172 + 1.597 1.530 -0.228
ENSG00000159247 E014 1.6295848 0.0848393312 0.0212005864 0.099987425 9 138174985 138175044 60 + 0.000 0.504 13.086
ENSG00000159247 E015 1.7910005 0.0797590711 0.1153201778 0.307997461 9 138175045 138175100 56 + 0.169 0.504 2.204
ENSG00000159247 E016 27.6893404 0.0059683706 0.5999827549 0.770208416 9 138175363 138175471 109 + 1.386 1.437 0.175
ENSG00000159247 E017 25.0607978 0.0074418310 0.4200839926 0.643722694 9 138175601 138175711 111 + 1.331 1.407 0.263
ENSG00000159247 E018 31.1344673 0.0012748745 0.2434172381 0.480479611 9 138175712 138175901 190 + 1.410 1.497 0.299
ENSG00000159247 E019 8.2377288 0.1710752112 0.5688935242 0.749452753 9 138176146 138176206 61 + 0.847 0.981 0.511
ENSG00000159247 E020 98.7529207 0.0008970683 0.3630054987 0.598157235 9 138176207 138176883 677 + 1.937 1.979 0.140
ENSG00000159247 E021 82.7042592 0.0030115517 0.2887627971 0.529430747 9 138176884 138177433 550 + 1.848 1.905 0.192