ENSG00000157800

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000326232 ENSG00000157800 HEK293_OSMI2_6hA HEK293_TMG_6hB SLC37A3 protein_coding protein_coding 31.89458 21.39062 40.59429 0.5034454 1.762421 0.9239794 14.539945 8.776416 20.764423 0.1481431 0.8710099 1.2414617 0.43723750 0.4109000 0.5122000 0.10130000 1.793116e-01 2.273914e-22 FALSE TRUE
ENST00000340308 ENSG00000157800 HEK293_OSMI2_6hA HEK293_TMG_6hB SLC37A3 protein_coding protein_coding 31.89458 21.39062 40.59429 0.5034454 1.762421 0.9239794 3.838056 2.364944 5.939195 0.3838919 0.3470480 1.3248010 0.11429167 0.1098667 0.1470000 0.03713333 6.233077e-01 2.273914e-22 FALSE TRUE
ENST00000469636 ENSG00000157800 HEK293_OSMI2_6hA HEK293_TMG_6hB SLC37A3 protein_coding protein_coding 31.89458 21.39062 40.59429 0.5034454 1.762421 0.9239794 2.051071 2.342581 0.000000 0.2441540 0.0000000 -7.8781007 0.07929167 0.1099333 0.0000000 -0.10993333 2.273914e-22 2.273914e-22   FALSE
MSTRG.30811.29 ENSG00000157800 HEK293_OSMI2_6hA HEK293_TMG_6hB SLC37A3 protein_coding   31.89458 21.39062 40.59429 0.5034454 1.762421 0.9239794 4.799922 3.958907 4.791736 0.7089886 0.9282659 0.2748144 0.16596667 0.1839000 0.1167333 -0.06716667 5.213038e-01 2.273914e-22   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_6hB HEK293_OSMI2_6hA log2fold_HEK293_OSMI2_6hA_HEK293_TMG_6hB
ENSG00000157800 E001 1.1417919 0.0964745180 0.92590723   7 140293693 140295352 1660 - 0.297 0.357 0.378
ENSG00000157800 E002 0.7874895 0.2348768263 0.94076057   7 140295985 140296137 153 - 0.241 0.264 0.176
ENSG00000157800 E003 0.7569420 0.0626674445 0.39879478   7 140297300 140297523 224 - 0.174 0.354 1.353
ENSG00000157800 E004 0.4764247 0.0217681645 0.82332404   7 140333752 140333753 2 - 0.174 0.153 -0.219
ENSG00000157800 E005 19.2231572 0.3406974977 0.37873296 0.61121523 7 140333754 140333790 37 - 1.226 1.386 0.561
ENSG00000157800 E006 498.1534151 1.7069003557 0.51497203 0.71163955 7 140333791 140334869 1079 - 2.596 2.801 0.683
ENSG00000157800 E007 82.8923711 0.8044537483 0.34661887 0.58422764 7 140334870 140334890 21 - 1.809 2.040 0.777
ENSG00000157800 E008 116.3097433 1.1828469745 0.43993289 0.65865628 7 140334891 140334988 98 - 1.961 2.178 0.724
ENSG00000157800 E009 128.2192284 1.2291955149 0.47700050 0.68497934 7 140334989 140335104 116 - 2.018 2.204 0.623
ENSG00000157800 E010 161.7607982 1.2862133680 0.41779680 0.64198547 7 140335105 140335289 185 - 2.085 2.338 0.849
ENSG00000157800 E011 74.3218935 0.7378020639 0.26749032 0.50715006 7 140335290 140335320 31 - 1.726 2.026 1.010
ENSG00000157800 E012 115.6387875 1.1639019137 0.40586940 0.63296836 7 140335321 140335436 116 - 1.945 2.189 0.819
ENSG00000157800 E013 61.4612683 0.7253892559 0.38762402 0.61859990 7 140335437 140335439 3 - 1.705 1.886 0.610
ENSG00000157800 E014 60.3655966 0.7148168155 0.37247214 0.60607603 7 140335440 140335454 15 - 1.693 1.883 0.642
ENSG00000157800 E015 55.8753943 0.6875258453 0.36799443 0.60241101 7 140335455 140335471 17 - 1.659 1.852 0.653
ENSG00000157800 E016 61.0413208 0.7297207848 0.39817333 0.62682780 7 140335472 140335504 33 - 1.706 1.878 0.580
ENSG00000157800 E017 97.9745633 0.0007970033 0.37633722 0.60927875 7 140337284 140337349 66 - 1.978 2.003 0.084
ENSG00000157800 E018 7.3413846 0.0359645339 0.18839672 0.41491500 7 140337350 140337825 476 - 0.792 1.047 0.966
ENSG00000157800 E019 114.6000437 0.0089789918 0.23691932 0.47302251 7 140343412 140343563 152 - 2.048 2.056 0.027
ENSG00000157800 E020 2.6784011 0.0624373725 0.38969263 0.62022054 7 140343564 140344086 523 - 0.472 0.681 0.949
ENSG00000157800 E021 73.4623849 0.0269214785 0.11089741 0.30042712 7 140345216 140345263 48 - 1.882 1.816 -0.221
ENSG00000157800 E022 83.5608752 0.0283158481 0.44879429 0.66484868 7 140345869 140345970 102 - 1.908 1.920 0.038
ENSG00000157800 E023 1.5988880 0.0235089935 0.50991752 0.70794408 7 140348458 140348625 168 - 0.435 0.356 -0.444
ENSG00000157800 E024 163.9954631 0.0302486844 0.31356016 0.55377129 7 140348626 140348767 142 - 2.205 2.199 -0.018
ENSG00000157800 E025 151.8547696 0.0341087619 0.39658969 0.62564725 7 140351273 140351360 88 - 2.168 2.172 0.014
ENSG00000157800 E026 131.8082644 0.0393177975 0.70515727 0.83882212 7 140351361 140351430 70 - 2.091 2.137 0.153
ENSG00000157800 E027 96.0360121 0.0270983183 0.32882149 0.56779465 7 140351431 140351451 21 - 1.974 1.971 -0.007
ENSG00000157800 E028 8.3355410 0.1700849184 0.69248682 0.83066820 7 140351452 140351519 68 - 0.950 0.990 0.150
ENSG00000157800 E029 15.6607327 0.1036116281 0.98150959 0.99254415 7 140351520 140351788 269 - 1.166 1.280 0.403
ENSG00000157800 E030 11.0941036 0.0839737507 0.76048155 0.87282892 7 140351789 140351875 87 - 1.006 1.161 0.558
ENSG00000157800 E031 4.5474637 0.1653876123 0.73108961 0.85482215 7 140351876 140351888 13 - 0.670 0.818 0.600
ENSG00000157800 E032 5.6881445 0.0059474484 0.75626788 0.87038430 7 140351889 140351969 81 - 0.773 0.866 0.366
ENSG00000157800 E033 138.3555663 0.0381714111 0.31379016 0.55400769 7 140352062 140352146 85 - 2.136 2.118 -0.059
ENSG00000157800 E034 6.5590335 0.0062377688 0.29369014 0.53431759 7 140352147 140352181 35 - 0.897 0.813 -0.325
ENSG00000157800 E035 144.4066035 0.0254539032 0.05336686 0.18760701 7 140355668 140355764 97 - 2.175 2.098 -0.258
ENSG00000157800 E036 163.5920070 0.0306730494 0.07435181 0.23345932 7 140358640 140358785 146 - 2.229 2.153 -0.255
ENSG00000157800 E037 98.5315717 0.0238026783 0.01379560 0.07352530 7 140364408 140364458 51 - 2.026 1.902 -0.419
ENSG00000157800 E038 104.4463950 0.0279344438 0.02193432 0.10236335 7 140364459 140364491 33 - 2.050 1.931 -0.400
ENSG00000157800 E039 127.6190530 0.0194911423 0.01598750 0.08177109 7 140369590 140369682 93 - 2.129 2.034 -0.320
ENSG00000157800 E040 20.5915519 0.0017167376 0.00878080 0.05285501 7 140375533 140375654 122 - 1.205 1.461 0.895
ENSG00000157800 E041 6.1174584 0.0127321838 0.33317580 0.57178733 7 140379214 140379258 45 - 0.773 0.954 0.699
ENSG00000157800 E042 5.3980057 0.0050552484 0.14407495 0.35351050 7 140379259 140379307 49 - 0.694 0.935 0.948
ENSG00000157800 E043 5.0289864 0.0268417018 0.04289985 0.16227963 7 140379308 140379471 164 - 0.623 0.971 1.387
ENSG00000157800 E044 2.8905013 0.0093280421 0.19767172 0.42666733 7 140379878 140380281 404 - 0.473 0.718 1.103
ENSG00000157800 E045 168.0400938 0.0179929258 0.04213817 0.16027302 7 140380282 140380390 109 - 2.235 2.175 -0.199
ENSG00000157800 E046 114.7589151 0.0265328497 0.08728615 0.25876676 7 140382438 140382482 45 - 2.072 2.007 -0.216
ENSG00000157800 E047 126.0375331 0.0305506543 0.09899075 0.28003241 7 140382483 140382596 114 - 2.112 2.046 -0.222
ENSG00000157800 E048 57.6343913 0.0382130510 0.43866687 0.65775823 7 140398416 140398550 135 - 1.753 1.751 -0.006
ENSG00000157800 E049 0.0000000       7 140398599 140398681 83 -      
ENSG00000157800 E050 0.0000000       7 140400336 140402601 2266 -      
ENSG00000157800 E051 0.0000000       7 140402602 140402822 221 -      
ENSG00000157800 E052 0.0000000       7 140404185 140404433 249 -