ENSG00000157625

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000288422 ENSG00000157625 HEK293_OSMI2_6hA HEK293_TMG_6hB TAB3 protein_coding protein_coding 4.681254 2.614163 7.219395 0.5333725 0.6913811 1.462017 2.04853075 0.75052346 2.8354127 0.38684005 0.4098062 1.9035732 0.3478875 0.238000000 0.39346667 0.15546667 0.77472964 0.01394718 FALSE  
ENST00000378930 ENSG00000157625 HEK293_OSMI2_6hA HEK293_TMG_6hB TAB3 protein_coding protein_coding 4.681254 2.614163 7.219395 0.5333725 0.6913811 1.462017 1.68227630 1.48286850 2.8466747 0.30037170 0.7467292 0.9362497 0.4564667 0.569666667 0.38350000 -0.18616667 0.39868131 0.01394718 FALSE  
ENST00000378933 ENSG00000157625 HEK293_OSMI2_6hA HEK293_TMG_6hB TAB3 protein_coding protein_coding 4.681254 2.614163 7.219395 0.5333725 0.6913811 1.462017 0.06903405 0.12371270 0.0000000 0.12371270 0.0000000 -3.7410646 0.0398250 0.079833333 0.00000000 -0.07983333 0.78622770 0.01394718 FALSE  
MSTRG.34054.8 ENSG00000157625 HEK293_OSMI2_6hA HEK293_TMG_6hB TAB3 protein_coding   4.681254 2.614163 7.219395 0.5333725 0.6913811 1.462017 0.25144449 0.01271907 0.6185246 0.01271907 0.1341180 4.7899934 0.0405625 0.003966667 0.09063333 0.08666667 0.01394718 0.01394718 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_6hB HEK293_OSMI2_6hA log2fold_HEK293_OSMI2_6hA_HEK293_TMG_6hB
ENSG00000157625 E001 0.0000000       X 30827442 30827442 1 -      
ENSG00000157625 E002 279.0553111 1.406317329 0.332215011 0.57103564 X 30827443 30830330 2888 - 2.293 2.598 1.018
ENSG00000157625 E003 89.6686388 0.746552554 0.497948697 0.69945278 X 30830331 30831230 900 - 1.890 1.977 0.295
ENSG00000157625 E004 18.0196314 0.268613841 0.752269422 0.86808120 X 30831231 30831261 31 - 1.236 1.265 0.103
ENSG00000157625 E005 22.6832396 0.261881936 0.538112519 0.72772353 X 30831262 30831300 39 - 1.311 1.395 0.291
ENSG00000157625 E006 44.4962905 0.493040285 0.431055997 0.65195140 X 30831301 30831575 275 - 1.583 1.695 0.382
ENSG00000157625 E007 20.9118801 0.001951411 0.294565032 0.53513015 X 30834051 30834152 102 - 1.307 1.317 0.037
ENSG00000157625 E008 10.2325851 0.007722863 0.479547600 0.68682737 X 30834621 30836700 2080 - 0.954 1.121 0.610
ENSG00000157625 E009 2.7776106 0.201278480 0.161137423 0.37850370 X 30836701 30836835 135 - 0.422 0.772 1.580
ENSG00000157625 E010 16.3572367 0.002230937 0.992833062 0.99807140 X 30842966 30842987 22 - 1.180 1.273 0.326
ENSG00000157625 E011 22.4662766 0.008010082 0.410724713 0.63655319 X 30842988 30843049 62 - 1.328 1.357 0.103
ENSG00000157625 E012 19.3686041 0.238524167 0.093013699 0.26932422 X 30843050 30845932 2883 - 1.327 1.092 -0.832
ENSG00000157625 E013 1.1058952 0.024981817 0.763004528   X 30845933 30846071 139 - 0.307 0.304 -0.019
ENSG00000157625 E014 3.1185921 0.058269797 0.019697185 0.09488923 X 30846072 30846550 479 - 0.671 0.302 -1.875
ENSG00000157625 E015 31.9462921 0.080824887 0.376667229 0.60959621 X 30846551 30846644 94 - 1.472 1.497 0.086
ENSG00000157625 E016 33.6858965 0.109943070 0.492282884 0.69551408 X 30852778 30852938 161 - 1.485 1.540 0.190
ENSG00000157625 E017 31.8429317 0.055698346 0.226254334 0.46093631 X 30854116 30854286 171 - 1.481 1.477 -0.013
ENSG00000157625 E018 134.2169332 0.021214188 0.004414791 0.03145909 X 30854287 30855562 1276 - 2.110 2.050 -0.202
ENSG00000157625 E019 38.0606861 0.117393567 0.077769268 0.24032846 X 30859487 30859678 192 - 1.590 1.440 -0.514
ENSG00000157625 E020 0.1614157 0.032361659 0.839909370   X 30859679 30859720 42 - 0.081 0.000 -8.038
ENSG00000157625 E021 22.5918930 0.102479531 0.114789718 0.30708781 X 30867115 30867218 104 - 1.366 1.240 -0.441
ENSG00000157625 E022 13.4915148 0.079185241 0.053874803 0.18880555 X 30867465 30867549 85 - 1.170 0.984 -0.674
ENSG00000157625 E023 9.6573016 0.016278489 0.318210179 0.55813726 X 30871699 30871801 103 - 1.001 0.982 -0.069
ENSG00000157625 E024 0.0000000       X 30871802 30871802 1 -      
ENSG00000157625 E025 0.4764247 0.021768165 1.000000000   X 30883588 30883740 153 - 0.149 0.178 0.306
ENSG00000157625 E026 4.3469336 0.226526137 0.662787075 0.81161571 X 30889114 30889323 210 - 0.592 0.873 1.153
ENSG00000157625 E027 0.0000000       X 30899071 30899163 93 -      
ENSG00000157625 E028 0.0000000       X 30975013 30975084 72 -