ENSG00000156802

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000287394 ENSG00000156802 HEK293_OSMI2_6hA HEK293_TMG_6hB ATAD2 protein_coding protein_coding 17.60295 3.360572 36.79956 0.4303711 1.306256 3.449015 9.353553 2.6524871 17.84525 0.45687622 0.8077834 2.745502 0.6786333 0.7790667 0.4862000 -0.2928667 0.0050917283 0.0001085909 FALSE TRUE
MSTRG.32048.5 ENSG00000156802 HEK293_OSMI2_6hA HEK293_TMG_6hB ATAD2 protein_coding   17.60295 3.360572 36.79956 0.4303711 1.306256 3.449015 7.881530 0.6574054 18.30947 0.07986031 1.4735022 4.778671 0.2848417 0.2007333 0.4963667 0.2956333 0.0001085909 0.0001085909 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_6hB HEK293_OSMI2_6hA log2fold_HEK293_OSMI2_6hA_HEK293_TMG_6hB
ENSG00000156802 E001 53.7513507 0.0050125023 9.040802e-06 1.924462e-04 8 123319850 123320501 652 - 1.483 1.801 1.081
ENSG00000156802 E002 119.1839668 0.0003320247 2.035328e-09 1.120770e-07 8 123320502 123320680 179 - 1.830 2.102 0.913
ENSG00000156802 E003 149.0420291 0.0019017917 1.534754e-08 6.904281e-07 8 123320681 123320911 231 - 1.928 2.183 0.856
ENSG00000156802 E004 132.6684903 0.0035079973 8.431757e-05 1.296782e-03 8 123320912 123321175 264 - 1.885 2.090 0.687
ENSG00000156802 E005 126.8570942 0.0019054883 1.618713e-02 8.248246e-02 8 123322938 123323066 129 - 1.877 2.003 0.424
ENSG00000156802 E006 154.0521050 0.0002707506 3.337589e-03 2.540790e-02 8 123325893 123326026 134 - 1.963 2.092 0.434
ENSG00000156802 E007 332.7537699 0.0002105445 5.719419e-05 9.356410e-04 8 123328190 123328579 390 - 2.297 2.418 0.403
ENSG00000156802 E008 197.9731706 0.0003269302 2.718637e-01 5.117415e-01 8 123333878 123334021 144 - 2.082 2.131 0.162
ENSG00000156802 E009 162.3825979 0.0002957030 5.435755e-02 1.899260e-01 8 123334200 123334322 123 - 1.992 2.079 0.290
ENSG00000156802 E010 195.8766071 0.0059609839 1.573477e-01 3.727386e-01 8 123336373 123336532 160 - 2.073 2.148 0.252
ENSG00000156802 E011 200.7001025 0.0017549114 7.517803e-01 8.678306e-01 8 123337625 123337821 197 - 2.089 2.108 0.063
ENSG00000156802 E012 159.4194495 0.0017006895 4.212505e-01 6.445851e-01 8 123339311 123339446 136 - 1.997 1.963 -0.114
ENSG00000156802 E013 0.4764247 0.0226994964 2.399643e-01   8 123344513 123344883 371 - 0.085 0.292 2.143
ENSG00000156802 E014 180.9088321 0.0002593899 2.172596e-01 4.501668e-01 8 123344884 123345069 186 - 2.051 2.003 -0.162
ENSG00000156802 E015 176.9144289 0.0012262740 1.909538e-01 4.180958e-01 8 123346086 123346272 187 - 2.043 1.986 -0.191
ENSG00000156802 E016 134.8159670 0.0037632071 1.359275e-01 3.412111e-01 8 123346618 123346750 133 - 1.929 1.845 -0.283
ENSG00000156802 E017 214.9244127 0.0003451798 3.473032e-01 5.848065e-01 8 123347092 123347406 315 - 2.125 2.092 -0.108
ENSG00000156802 E018 58.2125917 0.0006908938 5.958014e-02 2.018247e-01 8 123348183 123348186 4 - 1.576 1.429 -0.504
ENSG00000156802 E019 108.3988408 0.0004336680 2.571356e-02 1.144297e-01 8 123348187 123348273 87 - 1.840 1.714 -0.425
ENSG00000156802 E020 145.1809740 0.0005672973 3.565131e-01 5.929768e-01 8 123349285 123349421 137 - 1.956 1.916 -0.133
ENSG00000156802 E021 75.4645181 0.0025776932 8.316376e-01 9.147691e-01 8 123349422 123349444 23 - 1.669 1.689 0.066
ENSG00000156802 E022 0.6434498 0.0195210033 1.000000e+00   8 123356100 123356388 289 - 0.157 0.000 -9.092
ENSG00000156802 E023 117.2645525 0.0009691625 5.017925e-01 7.021051e-01 8 123356389 123356477 89 - 1.855 1.896 0.136
ENSG00000156802 E024 159.1681131 0.0020798365 1.128316e-01 3.038985e-01 8 123357562 123357736 175 - 1.984 2.064 0.269
ENSG00000156802 E025 64.3086452 0.0024657266 5.951742e-01 7.671326e-01 8 123359221 123359243 23 - 1.600 1.644 0.151
ENSG00000156802 E026 111.1159418 0.0045477130 3.790320e-01 6.114396e-01 8 123359244 123359336 93 - 1.844 1.793 -0.170
ENSG00000156802 E027 114.2386666 0.0017178679 4.292515e-01 6.504673e-01 8 123359577 123359685 109 - 1.855 1.814 -0.137
ENSG00000156802 E028 123.5616620 0.0004713583 3.115815e-02 1.308126e-01 8 123361539 123361646 108 - 1.894 1.781 -0.382
ENSG00000156802 E029 133.4142792 0.0003427813 1.917279e-02 9.305550e-02 8 123369058 123369175 118 - 1.927 1.808 -0.401
ENSG00000156802 E030 0.3337900 0.0309797395 1.180887e-01   8 123369273 123369388 116 - 0.045 0.292 3.143
ENSG00000156802 E031 188.2211079 0.0002668992 1.480035e-04 2.074308e-03 8 123369821 123370022 202 - 2.080 1.911 -0.567
ENSG00000156802 E032 71.7519006 0.0005497682 6.987037e-05 1.108002e-03 8 123370023 123370024 2 - 1.677 1.362 -1.080
ENSG00000156802 E033 142.7213334 0.0005717611 6.779472e-05 1.079724e-03 8 123370903 123370990 88 - 1.965 1.752 -0.716
ENSG00000156802 E034 154.6775153 0.0016885184 6.165144e-04 6.723499e-03 8 123371236 123371338 103 - 1.995 1.814 -0.610
ENSG00000156802 E035 178.4550711 0.0002648206 1.529724e-04 2.134262e-03 8 123371670 123371835 166 - 2.058 1.885 -0.582
ENSG00000156802 E036 77.7202442 0.0004974347 7.054730e-04 7.490187e-03 8 123372637 123372661 25 - 1.706 1.459 -0.843
ENSG00000156802 E037 70.5222993 0.0005157623 3.586015e-03 2.685378e-02 8 123372662 123372686 25 - 1.662 1.445 -0.745
ENSG00000156802 E038 108.0401841 0.0003722611 5.141546e-04 5.805537e-03 8 123380529 123380677 149 - 1.845 1.635 -0.710
ENSG00000156802 E039 0.0000000       8 123380678 123380914 237 -      
ENSG00000156802 E040 0.1723744 0.0404860690 3.405195e-02   8 123396183 123396186 4 - 0.000 0.292 13.341
ENSG00000156802 E041 63.6276748 0.0011443053 1.657843e-01 3.848488e-01 8 123396187 123396447 261 - 1.613 1.513 -0.341
ENSG00000156802 E042 0.0000000       8 123400743 123401175 433 -      
ENSG00000156802 E043 1.2139885 0.0322853176 4.534773e-01   8 123412080 123412177 98 - 0.271 0.000 -10.086
ENSG00000156802 E044 1.7447156 0.0957948866 3.071781e-02 1.295060e-01 8 123416248 123416350 103 - 0.243 0.687 2.367