ENSG00000156650

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000287239 ENSG00000156650 HEK293_OSMI2_6hA HEK293_TMG_6hB KAT6B protein_coding protein_coding 5.006066 4.470517 7.024086 1.13055 0.2934488 0.6506978 1.5914834 1.222578 2.4159811 0.1891389 0.6538078 0.9768896 0.29446667 0.3029000 0.34750000 0.04460000 9.631500e-01 3.641746e-09 FALSE TRUE
ENST00000372711 ENSG00000156650 HEK293_OSMI2_6hA HEK293_TMG_6hB KAT6B protein_coding protein_coding 5.006066 4.470517 7.024086 1.13055 0.2934488 0.6506978 0.2020895 0.000000 0.6858724 0.0000000 0.6858724 6.1207509 0.04032500 0.0000000 0.09373333 0.09373333 9.318910e-01 3.641746e-09 FALSE TRUE
ENST00000372714 ENSG00000156650 HEK293_OSMI2_6hA HEK293_TMG_6hB KAT6B protein_coding protein_coding 5.006066 4.470517 7.024086 1.13055 0.2934488 0.6506978 0.1604541 0.000000 0.7075783 0.0000000 0.0882282 6.1650644 0.02442917 0.0000000 0.10056667 0.10056667 3.278270e-07 3.641746e-09 FALSE TRUE
ENST00000372724 ENSG00000156650 HEK293_OSMI2_6hA HEK293_TMG_6hB KAT6B protein_coding protein_coding 5.006066 4.470517 7.024086 1.13055 0.2934488 0.6506978 0.1697766 0.000000 0.3481740 0.0000000 0.1741032 5.1625886 0.02742083 0.0000000 0.05080000 0.05080000 3.913113e-01 3.641746e-09 FALSE TRUE
ENST00000648370 ENSG00000156650 HEK293_OSMI2_6hA HEK293_TMG_6hB KAT6B protein_coding protein_coding 5.006066 4.470517 7.024086 1.13055 0.2934488 0.6506978 0.8805091 0.721090 1.2992119 0.2254664 0.6554648 0.8405776 0.16886667 0.1677333 0.18873333 0.02100000 9.779585e-01 3.641746e-09 FALSE TRUE
ENST00000649006 ENSG00000156650 HEK293_OSMI2_6hA HEK293_TMG_6hB KAT6B protein_coding protein_coding 5.006066 4.470517 7.024086 1.13055 0.2934488 0.6506978 1.0237920 2.228826 0.0000000 0.9522945 0.0000000 -7.8065987 0.24454583 0.4514333 0.00000000 -0.45143333 3.641746e-09 3.641746e-09 FALSE TRUE
ENST00000649463 ENSG00000156650 HEK293_OSMI2_6hA HEK293_TMG_6hB KAT6B protein_coding protein_coding 5.006066 4.470517 7.024086 1.13055 0.2934488 0.6506978 0.2299996 0.000000 0.6571737 0.0000000 0.6571737 6.0599906 0.03292500 0.0000000 0.08980000 0.08980000 9.309740e-01 3.641746e-09 FALSE TRUE
ENST00000650232 ENSG00000156650 HEK293_OSMI2_6hA HEK293_TMG_6hB KAT6B protein_coding protein_coding 5.006066 4.470517 7.024086 1.13055 0.2934488 0.6506978 0.2120066 0.000000 0.0000000 0.0000000 0.0000000 0.0000000 0.05840833 0.0000000 0.00000000 0.00000000   3.641746e-09 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

No results under this category.

Splicing

All exons whithin this gene region are shown and numbering below.

No results under this category.

Transcripts

All isoforms whithin this gene region are shown below.

No results under this category.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_6hB HEK293_OSMI2_6hA log2fold_HEK293_OSMI2_6hA_HEK293_TMG_6hB
ENSG00000156650 E001 0.0000000       10 74824927 74824935 9 +      
ENSG00000156650 E002 0.4349185 0.021768165 7.581612e-01   10 74824936 74825254 319 +      
ENSG00000156650 E003 0.1308682 0.030674128 3.728619e-01   10 74825255 74825356 102 +      
ENSG00000156650 E004 0.0000000       10 74825357 74825360 4 +      
ENSG00000156650 E005 0.0000000       10 74825484 74825491 8 +      
ENSG00000156650 E006 0.0000000       10 74825492 74825498 7 +      
ENSG00000156650 E007 0.0000000       10 74825499 74825526 28 +      
ENSG00000156650 E008 0.0000000       10 74825527 74825534 8 +      
ENSG00000156650 E009 0.0000000       10 74825535 74825535 1 +      
ENSG00000156650 E010 0.1426347 0.031722289 6.418087e-01   10 74825536 74825557 22 +      
ENSG00000156650 E011 0.1426347 0.031722289 6.418087e-01   10 74825558 74825567 10 +      
ENSG00000156650 E012 0.8383617 0.027010510 9.103614e-01   10 74825568 74825584 17 +      
ENSG00000156650 E013 1.9865032 0.011967972 8.181272e-01 0.9069811535 10 74825585 74825613 29 +      
ENSG00000156650 E014 2.8514683 0.007897814 7.364630e-01 0.8582491511 10 74825614 74825674 61 +      
ENSG00000156650 E015 0.0000000       10 74825675 74825766 92 +      
ENSG00000156650 E016 0.4514866 0.021804237 7.534573e-01   10 74826413 74826418 6 +      
ENSG00000156650 E017 0.7743180 0.017874523 2.900678e-01   10 74826419 74826448 30 +      
ENSG00000156650 E018 0.9051861 0.016209660 6.345942e-01   10 74826449 74826469 21 +      
ENSG00000156650 E019 1.2201952 0.013765399 7.653664e-01   10 74826470 74826551 82 +      
ENSG00000156650 E020 1.2671232 0.013696863 7.563098e-01   10 74826552 74826561 10 +      
ENSG00000156650 E021 1.4285389 0.012726464 5.616009e-01 0.7443958635 10 74826562 74826579 18 +      
ENSG00000156650 E022 1.7208227 0.011885836 6.608639e-01 0.8104820690 10 74826580 74826595 16 +      
ENSG00000156650 E023 1.4285389 0.012726464 5.616009e-01 0.7443958635 10 74826596 74826599 4 +      
ENSG00000156650 E024 1.5899546 0.012037490 4.084505e-01 0.6348495111 10 74826600 74826602 3 +      
ENSG00000156650 E025 4.9419777 0.005760114 9.293713e-01 0.9667257109 10 74826603 74826627 25 +      
ENSG00000156650 E026 4.8111096 0.005940137 7.693356e-01 0.8782425928 10 74826628 74826634 7 +      
ENSG00000156650 E027 8.3261801 0.008605186 1.554662e-01 0.3701349730 10 74826635 74826785 151 +      
ENSG00000156650 E028 0.1426347 0.031722289 6.418087e-01   10 74826881 74826943 63 +      
ENSG00000156650 E029 0.0000000       10 74827058 74827114 57 +      
ENSG00000156650 E030 0.0000000       10 74827137 74827270 134 +      
ENSG00000156650 E031 11.4925554 0.020171293 5.836415e-02 0.1991115853 10 74838683 74838752 70 +      
ENSG00000156650 E032 0.6268817 0.057519916 8.285877e-02   10 74838753 74838783 31 +      
ENSG00000156650 E033 11.2562255 0.004057361 1.920959e-05 0.0003695740 10 74842600 74842619 20 +      
ENSG00000156650 E034 34.9969635 0.015668446 7.460056e-05 0.0011709853 10 74842620 74842863 244 +      
ENSG00000156650 E035 16.7207141 0.015563943 2.396306e-02 0.1089784435 10 74842864 74842882 19 +      
ENSG00000156650 E036 81.0103076 0.014037428 4.553315e-05 0.0007681875 10 74842883 74843478 596 +      
ENSG00000156650 E037 1.3923819 0.012566280 4.524805e-01 0.6675153081 10 74843479 74847290 3812 +      
ENSG00000156650 E038 0.0000000       10 74907165 74907546 382 +      
ENSG00000156650 E039 0.0000000       10 74908488 74908597 110 +      
ENSG00000156650 E040 26.2132228 0.012624899 4.107510e-03 0.0297681970 10 74959970 74960078 109 +      
ENSG00000156650 E041 0.1614157 0.032794178 6.411760e-01   10 74960079 74962584 2506 +      
ENSG00000156650 E042 26.3621319 0.019353477 6.710425e-03 0.0432545554 10 74969660 74969775 116 +      
ENSG00000156650 E043 0.1614157 0.032794178 6.411760e-01   10 74969776 74970019 244 +      
ENSG00000156650 E044 21.6255563 0.055218290 2.006686e-01 0.4305676550 10 74970020 74970101 82 +      
ENSG00000156650 E045 0.3559677 0.905952418 5.229926e-01   10 74970102 74970750 649 +      
ENSG00000156650 E046 32.1252561 0.025019875 3.632397e-03 0.0271022485 10 74972507 74972639 133 +      
ENSG00000156650 E047 26.0149863 0.004869992 4.523268e-05 0.0007640293 10 74975399 74975454 56 +      
ENSG00000156650 E048 48.7309723 0.027088575 3.734287e-05 0.0006506956 10 74975455 74975781 327 +      
ENSG00000156650 E049 20.3973904 0.017021279 1.737011e-02 0.0868111835 10 74975782 74975945 164 +      
ENSG00000156650 E050 35.6317824 0.004285756 8.174431e-03 0.0501338530 10 74975946 74976330 385 +      
ENSG00000156650 E051 1.6056652 0.034722327 1.550294e-01 0.3695085603 10 74976331 74976520 190 +      
ENSG00000156650 E052 5.5335941 0.057458715 6.299208e-02 0.2094312689 10 74976521 74977315 795 +      
ENSG00000156650 E053 36.0828083 0.083248204 9.883741e-02 0.2797587297 10 74977316 74977437 122 +      
ENSG00000156650 E054 32.8943570 0.101190610 9.809534e-02 0.2784363264 10 74979224 74979339 116 +      
ENSG00000156650 E055 30.0965479 0.033443849 5.330804e-03 0.0363425600 10 74981787 74981928 142 +      
ENSG00000156650 E056 1.8263727 0.012932168 8.547487e-01 0.9274490900 10 74981929 74985079 3151 +      
ENSG00000156650 E057 37.8427275 0.026751352 4.060474e-02 0.1563218449 10 74985080 74985241 162 +      
ENSG00000156650 E058 0.5117739 0.034140432 7.589680e-01   10 74985329 74989018 3690 +      
ENSG00000156650 E059 32.1288226 0.005407608 1.356895e-01 0.3408757772 10 74989019 74989112 94 +      
ENSG00000156650 E060 0.6841482 0.445724092 8.491973e-01   10 74989113 74989957 845 +      
ENSG00000156650 E061 0.7145081 0.023320375 7.725536e-01   10 75017475 75019502 2028 +      
ENSG00000156650 E062 0.1779838 0.103884129 6.410469e-01   10 75019503 75019637 135 +      
ENSG00000156650 E063 0.6426420 0.019709892 7.758825e-01   10 75019638 75020581 944 +      
ENSG00000156650 E064 51.7001439 0.017425964 8.847512e-02 0.2609533281 10 75020582 75020813 232 +      
ENSG00000156650 E065 45.9420542 0.032395767 6.266495e-01 0.7882972642 10 75021126 75021285 160 +      
ENSG00000156650 E066 0.6294705 0.140532917 4.691801e-01   10 75021286 75021880 595 +      
ENSG00000156650 E067 64.9889619 0.012780856 9.203234e-01 0.9623837273 10 75021881 75022231 351 +      
ENSG00000156650 E068 0.3150090 0.039560048 8.198947e-01   10 75022232 75024232 2001 +      
ENSG00000156650 E069 72.6159683 0.057542219 3.736127e-01 0.6070342723 10 75024958 75025249 292 +      
ENSG00000156650 E070 3.1590532 0.015461838 2.014156e-03 0.0171576277 10 75025250 75026164 915 +      
ENSG00000156650 E071 537.3883507 1.736566714 3.164822e-01 0.5564916520 10 75028489 75032624 4136 +