ENSG00000156502

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000359655 ENSG00000156502 HEK293_OSMI2_6hA HEK293_TMG_6hB SUPV3L1 protein_coding protein_coding 40.31169 26.08683 45.42422 5.685351 2.237713 0.7999048 25.31086 14.909136 32.733566 3.767449 1.7906227 1.13404740 0.6241000 0.5597000 0.7205 0.1608000 0.066481356 0.006430275 FALSE TRUE
ENST00000497254 ENSG00000156502 HEK293_OSMI2_6hA HEK293_TMG_6hB SUPV3L1 protein_coding processed_transcript 40.31169 26.08683 45.42422 5.685351 2.237713 0.7999048 11.49825 8.751726 8.280316 1.828332 0.9165094 -0.07978804 0.2858292 0.3407667 0.1819 -0.1588667 0.006430275 0.006430275 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_6hB HEK293_OSMI2_6hA log2fold_HEK293_OSMI2_6hA_HEK293_TMG_6hB
ENSG00000156502 E001 0.6895701 0.0772737029 0.6289773110   10 69180192 69180233 42 + 0.176 0.264 0.745
ENSG00000156502 E002 4.6093715 0.0065232889 0.9465388900 0.975572310 10 69180234 69180249 16 + 0.738 0.748 0.041
ENSG00000156502 E003 32.3733058 0.0024993557 0.7226675052 0.849715439 10 69180250 69180280 31 + 1.525 1.504 -0.074
ENSG00000156502 E004 43.5497351 0.0078647108 0.3181109218 0.558038086 10 69180281 69180287 7 + 1.614 1.687 0.246
ENSG00000156502 E005 165.8761923 0.0014952193 0.8311831456 0.914470544 10 69180288 69180562 275 + 2.213 2.207 -0.018
ENSG00000156502 E006 10.1942885 0.0078226191 0.3992010046 0.627572434 10 69182520 69182654 135 + 0.997 1.091 0.341
ENSG00000156502 E007 110.8370369 0.0065730643 0.7345383921 0.857006112 10 69185987 69186064 78 + 2.042 2.019 -0.076
ENSG00000156502 E008 136.2896105 0.0020023273 0.3895298214 0.620083453 10 69186443 69186550 108 + 2.135 2.102 -0.111
ENSG00000156502 E009 0.1779838 0.0373327361 0.8447241659   10 69187433 69187466 34 + 0.097 0.000 -7.846
ENSG00000156502 E010 142.1493102 0.0003526718 0.0022638619 0.018820964 10 69187642 69187712 71 + 2.178 2.083 -0.318
ENSG00000156502 E011 134.1191738 0.0004091563 0.0104792427 0.060181138 10 69187713 69187756 44 + 2.148 2.065 -0.277
ENSG00000156502 E012 230.0898695 0.0002467038 0.0637371715 0.211110112 10 69189267 69189435 169 + 2.368 2.324 -0.149
ENSG00000156502 E013 181.7823716 0.0003051027 0.2353350812 0.471261240 10 69191655 69191766 112 + 2.263 2.231 -0.107
ENSG00000156502 E014 41.4004773 0.0369935401 0.2339466033 0.469694888 10 69191767 69193263 1497 + 1.572 1.674 0.345
ENSG00000156502 E015 144.0805415 0.0014346092 0.0292495387 0.125125810 10 69195188 69195265 78 + 2.178 2.101 -0.256
ENSG00000156502 E016 4.1190842 0.1187968985 0.5573018922 0.741359376 10 69195266 69195380 115 + 0.743 0.596 -0.625
ENSG00000156502 E017 176.4481281 0.0028549812 0.2521652927 0.490223416 10 69196992 69197083 92 + 2.253 2.210 -0.145
ENSG00000156502 E018 246.8563182 0.0002561266 0.3410705732 0.579012931 10 69198372 69198552 181 + 2.391 2.369 -0.072
ENSG00000156502 E019 158.3939885 0.0015837877 0.5107825012 0.708570850 10 69199104 69199197 94 + 2.199 2.176 -0.077
ENSG00000156502 E020 269.4006344 0.0005483041 0.8880759064 0.945624214 10 69200280 69200499 220 + 2.423 2.421 -0.007
ENSG00000156502 E021 143.1430811 0.0020969051 0.0975958472 0.277570624 10 69202439 69202519 81 + 2.123 2.185 0.206
ENSG00000156502 E022 244.9012363 0.0002275372 0.0108278065 0.061650010 10 69202867 69203043 177 + 2.355 2.414 0.197
ENSG00000156502 E023 2.2985929 0.2050299311 0.1097463739 0.298624577 10 69207776 69207792 17 + 0.349 0.685 1.638
ENSG00000156502 E024 286.8882317 0.0003491967 0.0065656664 0.042536909 10 69207793 69207941 149 + 2.422 2.482 0.200
ENSG00000156502 E025 439.4916364 0.0001805241 0.0004072053 0.004799947 10 69208600 69209099 500 + 2.608 2.668 0.199