ENSG00000155363

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000357443 ENSG00000155363 HEK293_OSMI2_6hA HEK293_TMG_6hB MOV10 protein_coding protein_coding 31.41085 37.34674 18.07885 2.139359 1.629278 -1.046268 7.4702627 8.1727998 2.613436 1.4671233 0.3744756 -1.6411371 0.22057083 0.21570000 0.14856667 -0.06713333 6.253937e-01 6.612607e-15 FALSE  
ENST00000369644 ENSG00000155363 HEK293_OSMI2_6hA HEK293_TMG_6hB MOV10 protein_coding protein_coding 31.41085 37.34674 18.07885 2.139359 1.629278 -1.046268 1.0977709 0.6930548 1.256945 0.4116718 0.1319060 0.8496445 0.03864167 0.01746667 0.06936667 0.05190000 4.463962e-01 6.612607e-15 FALSE  
ENST00000369645 ENSG00000155363 HEK293_OSMI2_6hA HEK293_TMG_6hB MOV10 protein_coding protein_coding 31.41085 37.34674 18.07885 2.139359 1.629278 -1.046268 10.0522096 14.8046043 5.834685 3.7666546 0.1432857 -1.3418229 0.32075000 0.38946667 0.32630000 -0.06316667 9.009651e-01 6.612607e-15 FALSE  
ENST00000471160 ENSG00000155363 HEK293_OSMI2_6hA HEK293_TMG_6hB MOV10 protein_coding processed_transcript 31.41085 37.34674 18.07885 2.139359 1.629278 -1.046268 4.4224618 4.2459425 2.086097 2.1234420 1.1805425 -1.0217735 0.12902500 0.11656667 0.10746667 -0.00910000 1.000000e+00 6.612607e-15 FALSE  
ENST00000685268 ENSG00000155363 HEK293_OSMI2_6hA HEK293_TMG_6hB MOV10 protein_coding retained_intron 31.41085 37.34674 18.07885 2.139359 1.629278 -1.046268 1.3424698 1.9484105 1.244070 0.4778482 0.4342910 -0.6430653 0.05049167 0.05406667 0.06690000 0.01283333 9.469760e-01 6.612607e-15 TRUE  
ENST00000687509 ENSG00000155363 HEK293_OSMI2_6hA HEK293_TMG_6hB MOV10 protein_coding retained_intron 31.41085 37.34674 18.07885 2.139359 1.629278 -1.046268 0.8112473 0.0000000 1.253017 0.0000000 0.2464236 6.9807299 0.03132500 0.00000000 0.06886667 0.06886667 6.612607e-15 6.612607e-15 TRUE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_6hB HEK293_OSMI2_6hA log2fold_HEK293_OSMI2_6hA_HEK293_TMG_6hB
ENSG00000155363 E001 0.0000000       1 112673141 112673451 311 +      
ENSG00000155363 E002 3.7085727 0.0063028515 0.6179088194 0.782391493 1 112674421 112674658 238 + 0.568 0.650 0.364
ENSG00000155363 E003 2.2845458 0.0097962069 0.0537697273 0.188531536 1 112674659 112674683 25 + 0.187 0.567 2.320
ENSG00000155363 E004 3.7588425 0.1030802160 0.9070827516 0.955658798 1 112674684 112674694 11 + 0.624 0.658 0.146
ENSG00000155363 E005 4.9311141 0.1580236941 0.9813016953 0.992422569 1 112674695 112674697 3 + 0.721 0.747 0.108
ENSG00000155363 E006 8.7963889 0.0265452652 0.1198886331 0.315676125 1 112674698 112674705 8 + 1.091 0.893 -0.731
ENSG00000155363 E007 15.0085584 0.0210840011 0.0127888314 0.069578962 1 112674706 112674708 3 + 1.343 1.078 -0.938
ENSG00000155363 E008 36.0890554 0.0064961183 0.1921052022 0.419513435 1 112674709 112674719 11 + 1.588 1.497 -0.313
ENSG00000155363 E009 44.4200471 0.0030693743 0.5606851676 0.743748496 1 112674720 112674729 10 + 1.634 1.600 -0.118
ENSG00000155363 E010 2.5562836 0.1169317266 0.4436708326 0.661145353 1 112674737 112674744 8 + 0.627 0.484 -0.660
ENSG00000155363 E011 18.3684794 0.0266675500 0.2965711435 0.537088080 1 112674745 112674831 87 + 1.322 1.204 -0.415
ENSG00000155363 E012 29.3206738 0.0012575646 0.9522389278 0.978093262 1 112674832 112674847 16 + 1.430 1.426 -0.014
ENSG00000155363 E013 84.9623315 0.0006050949 0.2794020281 0.519503921 1 112674848 112674911 64 + 1.845 1.895 0.165
ENSG00000155363 E014 100.3236700 0.0004100383 0.4866110869 0.691662416 1 112674912 112674989 78 + 1.930 1.959 0.097
ENSG00000155363 E015 95.1553800 0.0022304080 0.9772280807 0.990371198 1 112674990 112675049 60 + 1.930 1.929 -0.001
ENSG00000155363 E016 0.8515333 0.0302616814 0.5226837187   1 112675486 112676679 1194 + 0.318 0.199 -0.892
ENSG00000155363 E017 0.2027342 0.0364578580 1.0000000000   1 112676680 112676750 71 + 0.000 0.077 7.719
ENSG00000155363 E018 0.7558267 0.1079536271 0.9654330637   1 112685035 112685162 128 + 0.188 0.201 0.121
ENSG00000155363 E019 16.3562975 0.0110276080 0.1615936354 0.379116059 1 112686966 112687106 141 + 1.287 1.148 -0.493
ENSG00000155363 E020 38.1111604 0.0070706017 0.0002335736 0.003041418 1 112688328 112688934 607 + 1.710 1.449 -0.893
ENSG00000155363 E021 176.5179639 0.0040559017 0.9263256671 0.965278109 1 112688935 112689138 204 + 2.190 2.194 0.012
ENSG00000155363 E022 217.2024291 0.0099788771 0.2282346415 0.463179114 1 112689415 112689650 236 + 2.332 2.262 -0.234
ENSG00000155363 E023 100.2304151 0.0006513389 0.0378144233 0.149110892 1 112689840 112689866 27 + 2.011 1.929 -0.273
ENSG00000155363 E024 172.1944847 0.0046891806 0.1767751791 0.399449190 1 112689867 112689993 127 + 2.227 2.168 -0.199
ENSG00000155363 E025 167.9486483 0.0023888301 0.6692264972 0.815728953 1 112689994 112690098 105 + 2.185 2.170 -0.051
ENSG00000155363 E026 167.5368100 0.0016614404 0.1057119481 0.291874423 1 112691665 112691799 135 + 2.215 2.159 -0.185
ENSG00000155363 E027 184.4685044 0.0007275478 0.2182174335 0.451289096 1 112692761 112692929 169 + 2.243 2.206 -0.123
ENSG00000155363 E028 5.0420675 0.0640710899 0.9102834585 0.957311206 1 112693716 112693728 13 + 0.723 0.738 0.060
ENSG00000155363 E029 15.9308349 0.1073251190 0.6206071294 0.784239798 1 112693729 112694017 289 + 1.218 1.158 -0.214
ENSG00000155363 E030 163.3727892 0.0003359488 0.6083467431 0.775816162 1 112694018 112694172 155 + 2.173 2.157 -0.053
ENSG00000155363 E031 173.9559426 0.1358366217 0.3653937560 0.600256926 1 112694453 112694629 177 + 2.110 2.210 0.334
ENSG00000155363 E032 203.4144468 0.0121549077 0.1971416557 0.426025163 1 112694749 112694896 148 + 2.202 2.272 0.235
ENSG00000155363 E033 4.2732391 0.1633165148 0.9191569051 0.961794095 1 112694897 112695415 519 + 0.675 0.666 -0.038
ENSG00000155363 E034 224.7770049 0.0003695758 0.2197123853 0.453104100 1 112695416 112695574 159 + 2.272 2.307 0.115
ENSG00000155363 E035 186.1836847 0.0018856033 0.7127493585 0.843458069 1 112696148 112696251 104 + 2.206 2.219 0.044
ENSG00000155363 E036 5.6740111 0.0054434859 0.0873219803 0.258850402 1 112696252 112696283 32 + 0.932 0.703 -0.899
ENSG00000155363 E037 5.0762489 0.0422749419 0.9546635798 0.979253425 1 112696284 112696436 153 + 0.727 0.736 0.036
ENSG00000155363 E038 164.3631511 0.0003598942 0.9680963451 0.985901710 1 112696437 112696534 98 + 2.166 2.166 -0.002
ENSG00000155363 E039 163.6833835 0.0013279475 0.9421298285 0.973325915 1 112696630 112696738 109 + 2.165 2.163 -0.005
ENSG00000155363 E040 122.3557723 0.0031507563 0.9141850531 0.959192311 1 112696739 112696818 80 + 2.033 2.040 0.025
ENSG00000155363 E041 95.7021971 0.0021152197 0.4916541604 0.695095568 1 112696819 112696846 28 + 1.910 1.943 0.111
ENSG00000155363 E042 0.0000000       1 112697860 112697890 31 +      
ENSG00000155363 E043 180.3075562 0.0003272189 0.2620698472 0.501215475 1 112697994 112698111 118 + 2.177 2.212 0.117
ENSG00000155363 E044 106.7517355 0.0006103287 0.1635542238 0.382026944 1 112698287 112698307 21 + 1.933 1.990 0.190
ENSG00000155363 E045 153.8392314 0.0003935058 0.4052138122 0.632456169 1 112698308 112698367 60 + 2.112 2.140 0.093
ENSG00000155363 E046 213.5547052 0.0004374431 0.4627209572 0.674975615 1 112698368 112698478 111 + 2.258 2.279 0.069
ENSG00000155363 E047 29.1979253 0.1879454939 0.2150208027 0.447592334 1 112698479 112698637 159 + 1.568 1.359 -0.722
ENSG00000155363 E048 20.7578044 0.0992588381 0.2901994037 0.530798670 1 112698638 112698656 19 + 1.386 1.235 -0.528
ENSG00000155363 E049 27.3988047 0.1099623083 0.2867658286 0.527488551 1 112698657 112698714 58 + 1.497 1.354 -0.492
ENSG00000155363 E050 206.2945764 0.0003795545 0.3630669866 0.598210455 1 112698715 112698789 75 + 2.280 2.254 -0.085
ENSG00000155363 E051 23.8760549 0.0553240686 0.0867431199 0.257775822 1 112698790 112699213 424 + 1.488 1.269 -0.759
ENSG00000155363 E052 11.0563967 0.1254928156 0.4136087654 0.638710593 1 112699214 112699404 191 + 1.122 0.989 -0.487
ENSG00000155363 E053 7.1542654 0.1759749514 0.3737379542 0.607135142 1 112699405 112699457 53 + 0.961 0.820 -0.539
ENSG00000155363 E054 16.1318526 0.3316369181 0.3136002037 0.553820674 1 112699458 112699612 155 + 1.273 1.140 -0.472
ENSG00000155363 E055 11.0468473 0.2727664559 0.5816160019 0.758179647 1 112699613 112699662 50 + 1.080 1.006 -0.273
ENSG00000155363 E056 11.2678852 0.2123360932 0.4684529884 0.679009336 1 112699663 112699684 22 + 1.116 1.002 -0.416
ENSG00000155363 E057 110.7490778 0.0011452551 0.2537716195 0.492129332 1 112699685 112699686 2 + 2.026 1.981 -0.152
ENSG00000155363 E058 232.0662653 0.0010416525 0.3206392851 0.560251104 1 112699687 112699810 124 + 2.287 2.316 0.096
ENSG00000155363 E059 3.2857960 0.0200047966 0.7387146830 0.859682925 1 112699811 112699893 83 + 0.627 0.569 -0.257
ENSG00000155363 E060 181.0730787 0.0056250011 0.3583377985 0.594492150 1 112699894 112699982 89 + 2.170 2.213 0.144
ENSG00000155363 E061 38.5586701 0.1319153251 0.3498470652 0.587110680 1 112699983 112700218 236 + 1.634 1.503 -0.445
ENSG00000155363 E062 217.5839975 0.0046468842 0.0312568449 0.131094099 1 112700219 112700310 92 + 2.211 2.303 0.307
ENSG00000155363 E063 140.2989234 0.0036584758 0.0237107848 0.108198333 1 112700311 112700340 30 + 2.015 2.117 0.340
ENSG00000155363 E064 2.3143532 0.0316295813 0.6789309772 0.822054638 1 112700341 112700395 55 + 0.418 0.495 0.395
ENSG00000155363 E065 2.1908301 0.0097626513 0.1889989958 0.415702324 1 112700396 112700415 20 + 0.627 0.405 -1.070
ENSG00000155363 E066 302.7594826 0.0019467567 0.1429991130 0.351975337 1 112700416 112700756 341 + 2.392 2.436 0.147