ENSG00000152683

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000282587 ENSG00000152683 HEK293_OSMI2_6hA HEK293_TMG_6hB SLC30A6 protein_coding protein_coding 10.20946 2.588677 15.00708 0.5748524 0.6375787 2.530755 4.31629674 0.65004155 6.0958249 0.40203985 0.77811961 3.209557 0.41393333 0.282733333 0.4076000 0.12486667 0.854826796 0.002977631 FALSE TRUE
ENST00000357055 ENSG00000152683 HEK293_OSMI2_6hA HEK293_TMG_6hB SLC30A6 protein_coding protein_coding 10.20946 2.588677 15.00708 0.5748524 0.6375787 2.530755 0.07444635 0.59557080 0.0000000 0.59557080 0.00000000 -5.920224 0.02260000 0.180800000 0.0000000 -0.18080000 0.713123269 0.002977631 FALSE TRUE
ENST00000379343 ENSG00000152683 HEK293_OSMI2_6hA HEK293_TMG_6hB SLC30A6 protein_coding protein_coding 10.20946 2.588677 15.00708 0.5748524 0.6375787 2.530755 0.43547673 0.27517601 0.6276296 0.09831876 0.09157125 1.160866 0.05240833 0.112266667 0.0416000 -0.07066667 0.312905298 0.002977631 FALSE TRUE
ENST00000435660 ENSG00000152683 HEK293_OSMI2_6hA HEK293_TMG_6hB SLC30A6 protein_coding protein_coding 10.20946 2.588677 15.00708 0.5748524 0.6375787 2.530755 0.88858598 0.03008558 2.0327947 0.03008558 0.28141650 5.671317 0.06262917 0.009966667 0.1365333 0.12656667 0.002977631 0.002977631 FALSE TRUE
MSTRG.18176.3 ENSG00000152683 HEK293_OSMI2_6hA HEK293_TMG_6hB SLC30A6 protein_coding   10.20946 2.588677 15.00708 0.5748524 0.6375787 2.530755 1.88233742 0.33139707 3.2455749 0.16602864 1.05487253 3.253390 0.16620000 0.105300000 0.2144333 0.10913333 0.744240908 0.002977631 FALSE TRUE
MSTRG.18176.4 ENSG00000152683 HEK293_OSMI2_6hA HEK293_TMG_6hB SLC30A6 protein_coding   10.20946 2.588677 15.00708 0.5748524 0.6375787 2.530755 0.68950933 0.49294721 1.3870166 0.24956193 0.33272408 1.473870 0.09576250 0.243466667 0.0943000 -0.14916667 0.907314264 0.002977631 FALSE TRUE
MSTRG.18176.5 ENSG00000152683 HEK293_OSMI2_6hA HEK293_TMG_6hB SLC30A6 protein_coding   10.20946 2.588677 15.00708 0.5748524 0.6375787 2.530755 0.60914398 0.18687136 0.0000000 0.18687136 0.00000000 -4.299181 0.05714167 0.056733333 0.0000000 -0.05673333 0.633504357 0.002977631 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_6hB HEK293_OSMI2_6hA log2fold_HEK293_OSMI2_6hA_HEK293_TMG_6hB
ENSG00000152683 E001 0.1723744 0.079596487 0.107714617   2 32165841 32165846 6 + 0.000 0.246 31.769
ENSG00000152683 E002 0.3503582 0.146816168 0.333234962   2 32165847 32165847 1 + 0.056 0.247 2.478
ENSG00000152683 E003 0.8136113 0.241852170 1.000000000   2 32165848 32165854 7 + 0.189 0.247 0.488
ENSG00000152683 E004 0.9750270 0.024025537 0.878146629   2 32165855 32165860 6 + 0.226 0.246 0.159
ENSG00000152683 E005 1.7798925 0.014156229 0.344612284 0.58216118 2 32165861 32165863 3 + 0.374 0.246 -0.842
ENSG00000152683 E006 2.2375362 0.013331386 0.611012531 0.77761588 2 32165864 32165868 5 + 0.421 0.402 -0.103
ENSG00000152683 E007 5.4897780 0.074600681 0.799268877 0.89588826 2 32165869 32165881 13 + 0.700 0.744 0.181
ENSG00000152683 E008 16.4296056 0.097493762 0.299036034 0.53945690 2 32165882 32165903 22 + 1.121 1.084 -0.136
ENSG00000152683 E009 7.5417380 0.180436128 0.061355979 0.20583485 2 32165904 32166105 202 + 0.665 1.219 2.101
ENSG00000152683 E010 7.3638219 0.180906823 0.149942079 0.36222902 2 32166106 32166189 84 + 0.690 1.145 1.736
ENSG00000152683 E011 41.0123008 0.080980260 0.058729470 0.19992622 2 32171287 32171373 87 + 1.506 1.389 -0.403
ENSG00000152683 E012 53.3648978 0.040004450 0.008112757 0.04984200 2 32174063 32174147 85 + 1.620 1.479 -0.482
ENSG00000152683 E013 41.7879216 0.045718393 0.028017590 0.12131123 2 32175319 32175361 43 + 1.511 1.392 -0.410
ENSG00000152683 E014 4.0737564 0.006855504 0.321652912 0.56117596 2 32177477 32177596 120 + 0.539 0.802 1.119
ENSG00000152683 E015 54.4138041 0.067383758 0.020595898 0.09801203 2 32184273 32184338 66 + 1.628 1.470 -0.543
ENSG00000152683 E016 0.1614157 0.032677582 1.000000000   2 32187152 32187303 152 + 0.056 0.000 -26.850
ENSG00000152683 E017 49.3460324 0.073910465 0.040075053 0.15491011 2 32192336 32192416 81 + 1.584 1.450 -0.456
ENSG00000152683 E018 46.3301545 0.101609673 0.077781520 0.24035320 2 32192918 32192953 36 + 1.556 1.419 -0.471
ENSG00000152683 E019 56.3811247 0.119980068 0.108776553 0.29702792 2 32193889 32193983 95 + 1.637 1.526 -0.380
ENSG00000152683 E020 0.8074543 0.514492107 1.000000000   2 32197318 32197343 26 + 0.193 0.240 0.402
ENSG00000152683 E021 31.3424257 0.185713517 0.556188182 0.74063460 2 32197344 32197392 49 + 1.373 1.391 0.062
ENSG00000152683 E022 60.6247508 0.087481551 0.467776913 0.67856222 2 32197707 32197826 120 + 1.644 1.701 0.193
ENSG00000152683 E023 64.6615973 0.017486749 0.110731050 0.30018324 2 32204590 32204692 103 + 1.679 1.697 0.061
ENSG00000152683 E024 50.7676112 0.010198928 0.243327937 0.48039015 2 32206886 32206933 48 + 1.571 1.624 0.180
ENSG00000152683 E025 43.9365271 0.047656582 0.651478645 0.80447376 2 32209493 32209561 69 + 1.495 1.630 0.462
ENSG00000152683 E026 594.1125344 1.964744421 0.463884131 0.67580742 2 32220213 32224379 4167 + 2.577 2.860 0.941